Topical anaesthesia and intravenous cannulation success in paediatric patients: a randomized double-blinded trial

Oxford journals
Publication Type:
Journal Article
British Journal of Anaesthesia, 2008, 100 (4), pp. 521 - 524
Issue Date:
Full metadata record
Files in This Item:
Filename Description SizeFormat
2007001827OK.pdf76.66 kBAdobe PDF
Background: It is not known whether the choice of topical anaesthetic influences the likelihood of successful i.v. cannulation in the paediatric population. The null hypothesis of this study was that no difference exists in the initial success rate of cannulation between two commonly used topical anaesthetics. Methods: A randomized double-blind trial conducted on patients between the age of 12 months and 12 yr presenting to a tertiary hospital emergency department. Patients requiring cannulation were randomized to either 4% amethocaine gel (AnGEL) or 5% lidocaine and prilocaine in a 1:1 emulsion (EMLA). The primary endpoint was success of initial attempt at i.v. cannulation. Results: One hundred and seventy-seven patients were analysed of 203 enrolled. The success rate of AnGEL (73/97, 75%) and EMLA (59/80, 74%) did not significantly differ ({chi}21 0.05, P=0.82). Conclusions: No difference exists in the cannulation success rates between the two anaesthetics. The choice of topical anaesthetic in paediatric cannulation should be based on other factors such as cost, time to anaesthesia, efficacy of the agent, and adverse effect profile.
Please use this identifier to cite or link to this item: