Probiotics to prevent Clostridium difficile infection in patients receiving antibiotics

Publication Type:
Journal Article
Citation:
JAMA - Journal of the American Medical Association, 2018, 320 (5), pp. 499 - 500
Issue Date:
2018-08-07
Full metadata record
© 2018 American Medical Association. All rights reserved. CLINICAL QUESTION In adults and children prescribed antibiotics, is co-administration of a probiotic associated with a lower risk of symptomatic Clostridium difficile infection without an increase in adverse events? BOTTOM LINE Moderate-quality evidence suggests that probiotics are associated with a lower risk of C difficile infection and very low–quality evidence suggests that probiotics are associated with fewer adverse events vs placebo or no treatment.
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