A protocol developing, disseminating and implementing a core outcome set for infertility.

Duffy, JMN; Bhattacharya, S; Curtis, C; Evers, JLH; Farquharson, RG; Franik, S; Khalaf, Y; Legro, RS; Lensen, S; Mol, BW; Niederberger, C; Ng, EHY; Repping, S; Strandell, A; Torrance, HL; Vail, A; van Wely, M; Vuong, NL; Wang, AY; Wang, R; Wilkinson, J; Youssef, MA; Farquhar, CM; COMMIT: Core Outcomes Measures for Infertility Trials

A protocol developing, disseminating and implementing a core outcome set for infertility.

Bhattacharya, S Curtis, C Evers, JLH

Farquharson, RG Franik, S Khalaf, Y Legro, RS Lensen, S Mol, BW Niederberger, C Ng, EHY Repping, S Strandell, A Torrance, HL Vail, A van Wely, M Vuong, NL

Wang, AY

Wang, R

Wilkinson, J

Youssef, MA Farquhar, CM COMMIT: Core Outcomes Measures for Infertility Trials

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Publication Type:: Journal Article
Citation:: Hum Reprod Open, 2018, 2018 (3), pp. hoy007 - ?
Issue Date:: 2018

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Field	Value	Language
dc.contributor.author	Duffy, JMN https://orcid.org/0000-0001-6127-9859	en_US
dc.contributor.author	Bhattacharya, S	en_US
dc.contributor.author	Curtis, C	en_US
dc.contributor.author	Evers, JLH https://orcid.org/0000-0001-8079-1436	en_US
dc.contributor.author	Farquharson, RG	en_US
dc.contributor.author	Franik, S	en_US
dc.contributor.author	Khalaf, Y	en_US
dc.contributor.author	Legro, RS	en_US
dc.contributor.author	Lensen, S	en_US
dc.contributor.author	Mol, BW	en_US
dc.contributor.author	Niederberger, C	en_US
dc.contributor.author	Ng, EHY	en_US
dc.contributor.author	Repping, S	en_US
dc.contributor.author	Strandell, A	en_US
dc.contributor.author	Torrance, HL	en_US
dc.contributor.author	Vail, A	en_US
dc.contributor.author	van Wely, M	en_US
dc.contributor.author	Vuong, NL https://orcid.org/0000-0001-6529-6912	en_US
dc.contributor.author	Wang, AY https://orcid.org/0000-0002-3656-4284	en_US
dc.contributor.author	Wang, R https://orcid.org/0000-0002-6622-8134	en_US
dc.contributor.author	Wilkinson, J https://orcid.org/0000-0003-3513-4677	en_US
dc.contributor.author	Youssef, MA	en_US
dc.contributor.author	Farquhar, CM	en_US
dc.contributor.author	COMMIT: Core Outcomes Measures for Infertility Trials	en_US
dc.date.available	2018-04-12	en_US
dc.date.issued	2018	en_US
dc.identifier.citation	Hum Reprod Open, 2018, 2018 (3), pp. hoy007 - ?	en_US
dc.identifier.uri	http://hdl.handle.net/10453/131718
dc.description.abstract	STUDY QUESTIONS: We aim to produce, disseminate and implement a core outcome set for future infertility research. WHAT IS KNOWN ALREADY: Randomized controlled trials (RCTs) evaluating infertility treatments have reported many different outcomes, which are often defined and measured in different ways. Such variation contributes to an inability to compare, contrast and combine results of individual RCTs. The development of a core outcome set will ensure outcomes important to key stakeholders are consistently collected and reported across future infertility research. STUDY DESIGN SIZE DURATION: This is a consensus study using the modified Delphi method. All stakeholders, including healthcare professionals, allied healthcare professionals, researchers and people with lived experience of infertility will be invited to participate. PARTICIPANTS/MATERIALS SETTING METHODS: An international steering group, including people with lived experience of infertility, healthcare professionals, allied healthcare professionals and researchers, has been formed to guide the development of this core outcome set. Potential core outcomes have been identified through a comprehensive literature review of RCTs evaluating treatments for infertility and will be entered into a modified Delphi method. Participants will be asked to score potential core outcomes on a nine-point Likert scale anchored between one (not important) and nine (critical). Repeated reflection and rescoring should promote convergence towards consensus 'core' outcomes. We will establish standardized definitions and recommend high-quality measurement instruments for individual core outcomes. STUDY FUNDING/COMPETING INTERESTS: This project is funded by the Royal Society of New Zealand Catalyst Fund (3712235). BWM reports consultancy fees from Guerbet, Merck, and ObsEva. R.S.L. reports consultancy fees from Abbvie, Bayer, Fractyl and Ogeda and research sponsorship from Ferring. S.B. is the Editor-in-Chief of Human Reproduction Open. The remaining authors declare no competing interests.	en_US
dc.language	eng	en_US
dc.relation.ispartof	Hum Reprod Open	en_US
dc.relation.isbasedon	10.1093/hropen/hoy007	en_US
dc.title	A protocol developing, disseminating and implementing a core outcome set for infertility.	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	2018	en_US
utslib.location.activity	England	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Public Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
utslib.copyright.status	open_access
pubs.issue	3	en_US
pubs.publication-status	Published online	en_US
pubs.volume	2018	en_US

Abstract:

STUDY QUESTIONS: We aim to produce, disseminate and implement a core outcome set for future infertility research. WHAT IS KNOWN ALREADY: Randomized controlled trials (RCTs) evaluating infertility treatments have reported many different outcomes, which are often defined and measured in different ways. Such variation contributes to an inability to compare, contrast and combine results of individual RCTs. The development of a core outcome set will ensure outcomes important to key stakeholders are consistently collected and reported across future infertility research. STUDY DESIGN SIZE DURATION: This is a consensus study using the modified Delphi method. All stakeholders, including healthcare professionals, allied healthcare professionals, researchers and people with lived experience of infertility will be invited to participate. PARTICIPANTS/MATERIALS SETTING METHODS: An international steering group, including people with lived experience of infertility, healthcare professionals, allied healthcare professionals and researchers, has been formed to guide the development of this core outcome set. Potential core outcomes have been identified through a comprehensive literature review of RCTs evaluating treatments for infertility and will be entered into a modified Delphi method. Participants will be asked to score potential core outcomes on a nine-point Likert scale anchored between one (not important) and nine (critical). Repeated reflection and rescoring should promote convergence towards consensus 'core' outcomes. We will establish standardized definitions and recommend high-quality measurement instruments for individual core outcomes. STUDY FUNDING/COMPETING INTERESTS: This project is funded by the Royal Society of New Zealand Catalyst Fund (3712235). BWM reports consultancy fees from Guerbet, Merck, and ObsEva. R.S.L. reports consultancy fees from Abbvie, Bayer, Fractyl and Ogeda and research sponsorship from Ferring. S.B. is the Editor-in-Chief of Human Reproduction Open. The remaining authors declare no competing interests.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/131718