The Myeloperoxidase-Derived Oxidant Hoscn Inhibits Protein Tyrosine Phosphatases And Modulates Cell Signalling Via The Mitogen-Activated Protein Kinase (Mapk) Pathway In Macrophages

Publisher:
Portland Press Ltd
Publication Type:
Journal Article
Citation:
Biochemical Journal, 2010, 430 pp. 161 - 169
Issue Date:
2010-01
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MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate by hydrogen peroxide to HOCl (hypochlorous acid), HOBr (hypobromous acid) and HOSCN (hypothiocyanous acid) respectively. Specificity constants indicate that SCN- is a majo
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