Herbal medicines for suppressing appetite: A systematic review of randomized clinical trials

Sahebkar-Khorasani, M; Jarahi, L; Cramer, H; Safarian, M; Naghedi-Baghdar, H; Salari, R; Behravanrad, P; Azizi, H

Herbal medicines for suppressing appetite: A systematic review of randomized clinical trials

Sahebkar-Khorasani, M Jarahi, L Cramer, H Safarian, M Naghedi-Baghdar, H Salari, R Behravanrad, P Azizi, H

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Publication Type:: Journal Article
Citation:: Complementary Therapies in Medicine, 2019, 44 pp. 242 - 252
Issue Date:: 2019-06-01

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Full metadata record

Field	Value	Language
dc.contributor.author	Sahebkar-Khorasani, M	en_US
dc.contributor.author	Jarahi, L	en_US
dc.contributor.author	Cramer, H	en_US
dc.contributor.author	Safarian, M	en_US
dc.contributor.author	Naghedi-Baghdar, H	en_US
dc.contributor.author	Salari, R	en_US
dc.contributor.author	Behravanrad, P	en_US
dc.contributor.author	Azizi, H	en_US
dc.date.available	2019-04-23	en_US
dc.date.issued	2019-06-01	en_US
dc.identifier.citation	Complementary Therapies in Medicine, 2019, 44 pp. 242 - 252	en_US
dc.identifier.issn	0965-2299	en_US
dc.identifier.uri	http://hdl.handle.net/10453/135406
dc.description.abstract	© 2019 Elsevier Ltd The suppression of appetite with herbal medicines has become very popular in recent years. We conducted this systematic review to evaluate the recent scientific evidence regarding herbal medicines that are used to suppress appetite. We retrieved clinical trials from PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Scientific Information Database, and IranMedex from January 1, 2013 to April 24, 2018. English and Persian language randomized clinical trials that used herbal medicines to suppress appetite in healthy or obese or overweight individuals were included. Risk of bias was assessed using Cochrane methodology. Out of 591 articles, 22 trials with 973 participants were included. One study on the Meratrim formulation which contained the Sphaeranthus indicus flower heads extract and Garcinia mangostana fruit, revealed longer-term evidence; while 6 studies on Ilex paraguariensis, Spinacia oleracea, Phaseolus vulgaris, Secale cereale, Sorghum bicolor and Plantago showed short-term evidence for suppressing appetite. No serious adverse events were reported. Despite some methodological concerns in the included studies, there is promising evidence for suppressing appetite with herbal medicines that needs to be confirmed in long-term clinical trials with adequate sample size and higher methodological quality with more attention to safety, effective dose and side effects.	en_US
dc.relation.ispartof	Complementary Therapies in Medicine	en_US
dc.relation.isbasedon	10.1016/j.ctim.2019.04.019	en_US
dc.subject.classification	Complementary & Alternative Medicine	en_US
dc.subject.mesh	Appetite	en_US
dc.subject.mesh	Drugs, Chinese Herbal	en_US
dc.subject.mesh	Herbal Medicine	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Phytotherapy	en_US
dc.subject.mesh	Plants, Medicinal	en_US
dc.subject.mesh	Randomized Controlled Trials as Topic	en_US
dc.title	Herbal medicines for suppressing appetite: A systematic review of randomized clinical trials	en_US
dc.type	Journal Article
utslib.citation.volume	44	en_US
utslib.for	1104 Complementary and Alternative Medicine	en_US
utslib.for	1701 Psychology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access
pubs.publication-status	Published	en_US
pubs.volume	44	en_US

Abstract:

© 2019 Elsevier Ltd The suppression of appetite with herbal medicines has become very popular in recent years. We conducted this systematic review to evaluate the recent scientific evidence regarding herbal medicines that are used to suppress appetite. We retrieved clinical trials from PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Scientific Information Database, and IranMedex from January 1, 2013 to April 24, 2018. English and Persian language randomized clinical trials that used herbal medicines to suppress appetite in healthy or obese or overweight individuals were included. Risk of bias was assessed using Cochrane methodology. Out of 591 articles, 22 trials with 973 participants were included. One study on the Meratrim formulation which contained the Sphaeranthus indicus flower heads extract and Garcinia mangostana fruit, revealed longer-term evidence; while 6 studies on Ilex paraguariensis, Spinacia oleracea, Phaseolus vulgaris, Secale cereale, Sorghum bicolor and Plantago showed short-term evidence for suppressing appetite. No serious adverse events were reported. Despite some methodological concerns in the included studies, there is promising evidence for suppressing appetite with herbal medicines that needs to be confirmed in long-term clinical trials with adequate sample size and higher methodological quality with more attention to safety, effective dose and side effects.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/135406