Rapid Softlithography Using 3D-Printed Molds

Razavi Bazaz, S; Kashaninejad, N; Azadi, S; Patel, K; Asadnia, M; Jin, D; Ebrahimi Warkiani, M

Rapid Softlithography Using 3D-Printed Molds

Razavi Bazaz, S

Kashaninejad, N

Azadi, S Patel, K Asadnia, M Jin, D

Ebrahimi Warkiani, M

Permalink

Publication Type:: Journal Article
Citation:: Advanced Materials Technologies, 2019, 4 (10)
Issue Date:: 2019-10-01

Closed Access

	Filename	Description	Size
	Rapid Softlithography Using 3D-Printed Molds.pdf	Published Version	2.49 MB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Razavi Bazaz, S https://orcid.org/0000-0002-6419-3361	en_US
dc.contributor.author	Kashaninejad, N https://orcid.org/0000-0002-4385-7771	en_US
dc.contributor.author	Azadi, S	en_US
dc.contributor.author	Patel, K	en_US
dc.contributor.author	Asadnia, M	en_US
dc.contributor.author	Jin, D https://orcid.org/0000-0003-1046-2666	en_US
dc.contributor.author	Ebrahimi Warkiani, M https://orcid.org/0000-0002-4184-1944	en_US
dc.date.issued	2019-10-01	en_US
dc.identifier.citation	Advanced Materials Technologies, 2019, 4 (10)	en_US
dc.identifier.uri	http://hdl.handle.net/10453/136222
dc.description.abstract	© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Polydimethylsiloxane (PDMS) is a long-standing material of significant interest in microfluidics due to its unique features. As such, rapid prototyping of PDMS-based microchannels is of great interest. The most prevalent and conventional method for fabrication of PDMS-based microchips relies on softlithography, the main drawback of which is the preparation of a master mold, which is costly and time-consuming. To prevent the attachment of PDMS to the master mold, silanization is necessary, which can be detrimental for cellular studies. Additionally, using coating the mold with a cell-compatible surfactant adds extra preprocessing time. Recent advances in 3D printing have shown great promise in expediting microfabrication. Nevertheless, current 3D printing techniques are sub-optimal for PDMS softlithography. The feasibility of producing master molds suitable for rapid softlithography is demonstrated using a newly developed 3D-printing resin. Moreover, the utility of this technique is showcased for a number of widely used applications, such as concentration gradient generation, particle separation, cell culture (to show biocompatibility of the process), and fluid mixing. This can open new opportunities for biologists and scientists with minimum knowledge of microfabrication to build functional microfluidic devices for their basic and applied research.	en_US
dc.relation	http://purl.org/au-research/grants/arc/DP180103003
dc.relation	http://purl.org/au-research/grants/arc/DP170103704
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT1143377
dc.relation.ispartof	Advanced Materials Technologies	en_US
dc.relation.isbasedon	10.1002/admt.201900425	en_US
dc.rights	info:eu-repo/semantics/closedAccess
dc.title	Rapid Softlithography Using 3D-Printed Molds	en_US
dc.type	Journal Article
utslib.citation.volume	10	en_US
utslib.citation.volume	4	en_US
utslib.for	0912 Materials Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	closed_access	*
pubs.issue	10	en_US
pubs.publication-status	Published	en_US
pubs.volume	4	en_US

Abstract:

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Polydimethylsiloxane (PDMS) is a long-standing material of significant interest in microfluidics due to its unique features. As such, rapid prototyping of PDMS-based microchannels is of great interest. The most prevalent and conventional method for fabrication of PDMS-based microchips relies on softlithography, the main drawback of which is the preparation of a master mold, which is costly and time-consuming. To prevent the attachment of PDMS to the master mold, silanization is necessary, which can be detrimental for cellular studies. Additionally, using coating the mold with a cell-compatible surfactant adds extra preprocessing time. Recent advances in 3D printing have shown great promise in expediting microfabrication. Nevertheless, current 3D printing techniques are sub-optimal for PDMS softlithography. The feasibility of producing master molds suitable for rapid softlithography is demonstrated using a newly developed 3D-printing resin. Moreover, the utility of this technique is showcased for a number of widely used applications, such as concentration gradient generation, particle separation, cell culture (to show biocompatibility of the process), and fluid mixing. This can open new opportunities for biologists and scientists with minimum knowledge of microfabrication to build functional microfluidic devices for their basic and applied research.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/136222