German value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30

Kemmler, G; Gamper, E; Nerich, V; Norman, R; Viney, R; Holzner, B; King, M

German value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30

Kemmler, G Gamper, E Nerich, V Norman, R Viney, R

Holzner, B King, M

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Publication Type:: Journal Article
Citation:: Quality of Life Research, 2019, 28 (12), pp. 3197 - 3211
Issue Date:: 2019-12-01

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Field	Value	Language
dc.contributor.author	Kemmler, G	en_US
dc.contributor.author	Gamper, E	en_US
dc.contributor.author	Nerich, V	en_US
dc.contributor.author	Norman, R	en_US
dc.contributor.author	Viney, R https://orcid.org/0000-0002-0039-9635	en_US
dc.contributor.author	Holzner, B	en_US
dc.contributor.author	King, M	en_US
dc.date.available	2019-08-23	en_US
dc.date.issued	2019-12-01	en_US
dc.identifier.citation	Quality of Life Research, 2019, 28 (12), pp. 3197 - 3211	en_US
dc.identifier.issn	0962-9343	en_US
dc.identifier.uri	http://hdl.handle.net/10453/138820
dc.description.abstract	© 2019, The Author(s). Purpose: The EORTC QLU-C10D is a new multi-attribute utility instrument derived from the EORTC QLQ-C30, a widely used cancer-specific quality of life questionnaire. It covers ten dimensions: physical, role, social, emotional functioning, pain, fatigue, sleep, appetite, nausea, and bowel problems. To allow national health attitudes to be reflected, country-specific valuations are being performed by collaboration of the Multi-Attribute Utility Cancer (MAUCa) Consortium and the EORTC. The purpose of this paper is to provide German value sets (utility weights) for the QLU-C10D. Methods: Valuations were run in a web-based setting in two general population samples of approximately 2000 adults in total. As the German version of the QLQ-C30 is presently undergoing a revision of the wording of one response category, valuations for both the current and the new version were performed (Germany 1 and 2). Utilities were elicited using a discrete choice experiment (DCE). Data were analyzed by conditional logistic regression and mixed logits. Results: Completion rates were 88.3% (1002/1135) and 90.4% (1016/1124) for Germany 1 and Germany 2 valuations, respectively. Dimensions with the largest impact on utility weights were, in this order: physical functioning, pain, role functioning, social functioning and nausea (same ordering for both German versions). Several violations of the logical ordering of levels were observed for Germany 1; this was largely improved for Germany 2. Conclusion: This study established German utility weights for the cancer-specific utility instrument QLU-C10D.	en_US
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT632662
dc.relation.ispartof	Quality of Life Research	en_US
dc.relation.isbasedon	10.1007/s11136-019-02283-w	en_US
dc.subject.classification	Health Policy & Services	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Neoplasms	en_US
dc.subject.mesh	Pain	en_US
dc.subject.mesh	Fatigue	en_US
dc.subject.mesh	Nausea	en_US
dc.subject.mesh	Logistic Models	en_US
dc.subject.mesh	Quality of Life	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Aged, 80 and over	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Germany	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Young Adult	en_US
dc.subject.mesh	Surveys and Questionnaires	en_US
dc.title	German value sets for the EORTC QLU-C10D, a cancer-specific utility instrument based on the EORTC QLQ-C30	en_US
dc.type	Journal Article
utslib.citation.volume	12	en_US
utslib.citation.volume	28	en_US
utslib.for	1112 Oncology and Carcinogenesis	en_US
utslib.for	1117 Public Health and Health Services	en_US
utslib.for	1701 Psychology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Business
pubs.organisational-group	/University of Technology Sydney/Strength - CHERE - Centre for Health Economics Research and Evaluation
utslib.copyright.status	closed_access
pubs.issue	12	en_US
pubs.publication-status	Published	en_US
pubs.volume	28	en_US

Abstract:

© 2019, The Author(s). Purpose: The EORTC QLU-C10D is a new multi-attribute utility instrument derived from the EORTC QLQ-C30, a widely used cancer-specific quality of life questionnaire. It covers ten dimensions: physical, role, social, emotional functioning, pain, fatigue, sleep, appetite, nausea, and bowel problems. To allow national health attitudes to be reflected, country-specific valuations are being performed by collaboration of the Multi-Attribute Utility Cancer (MAUCa) Consortium and the EORTC. The purpose of this paper is to provide German value sets (utility weights) for the QLU-C10D. Methods: Valuations were run in a web-based setting in two general population samples of approximately 2000 adults in total. As the German version of the QLQ-C30 is presently undergoing a revision of the wording of one response category, valuations for both the current and the new version were performed (Germany 1 and 2). Utilities were elicited using a discrete choice experiment (DCE). Data were analyzed by conditional logistic regression and mixed logits. Results: Completion rates were 88.3% (1002/1135) and 90.4% (1016/1124) for Germany 1 and Germany 2 valuations, respectively. Dimensions with the largest impact on utility weights were, in this order: physical functioning, pain, role functioning, social functioning and nausea (same ordering for both German versions). Several violations of the logical ordering of levels were observed for Germany 1; this was largely improved for Germany 2. Conclusion: This study established German utility weights for the cancer-specific utility instrument QLU-C10D.

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http://hdl.handle.net/10453/138820