Production of the biomimetic small diameter blood vessels for cardiovascular tissue engineering

Aydogdu, MO; Chou, J; Altun, E; Ekren, N; Cakmak, S; Eroglu, M; Osman, AA; Kutlu, O; Oner, ET; Avsar, G; Oktar, FN; Yilmaz, I; Gunduz, O

Production of the biomimetic small diameter blood vessels for cardiovascular tissue engineering

Aydogdu, MO Chou, J

Altun, E Ekren, N Cakmak, S Eroglu, M Osman, AA Kutlu, O Oner, ET Avsar, G Oktar, FN Yilmaz, I Gunduz, O

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Publisher:: TAYLOR & FRANCIS AS
Publication Type:: Journal Article
Citation:: International Journal of Polymeric Materials and Polymeric Biomaterials, 2019, 68, (5), pp. 243-255
Issue Date:: 2019

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Field	Value	Language
dc.contributor.author	Aydogdu, MO
dc.contributor.author	Chou, J https://orcid.org/0000-0002-7472-8016
dc.contributor.author	Altun, E
dc.contributor.author	Ekren, N
dc.contributor.author	Cakmak, S
dc.contributor.author	Eroglu, M
dc.contributor.author	Osman, AA
dc.contributor.author	Kutlu, O
dc.contributor.author	Oner, ET
dc.contributor.author	Avsar, G
dc.contributor.author	Oktar, FN
dc.contributor.author	Yilmaz, I
dc.contributor.author	Gunduz, O
dc.date.accessioned	2020-05-11T04:06:32Z
dc.date.available	2020-05-11T04:06:32Z
dc.date.issued	2019
dc.identifier.citation	International Journal of Polymeric Materials and Polymeric Biomaterials, 2019, 68, (5), pp. 243-255
dc.identifier.issn	0091-4037
dc.identifier.issn	1563-535X
dc.identifier.uri	http://hdl.handle.net/10453/140620
dc.description.abstract	© 2018 Taylor & Francis A novel biomimetic vascular graft scaffolds were produced by electrospinning method with the most superior characteristics to be a proper biomimetic small diameter blood vessel using Polycaprolactone(PCL), Ethyl Cellulose(EC) and Collagen Type-1 were used to create the most convenient synergy of a natural and synthetic polymer to achieve similarity to native small diameter blood vessels. Scanning Electron Microscopy(SEM), Fourier Transform Infrared Spectroscopy(FTIR), Differential Scanning Calorimetry Analysis(DSC), tensile measurement tests, and in-vitro and in-vivo applications were performed. Results indicated significant properties such as having 39.33 nm minimum, 104.98 nm average fiber diameter, 3.2 MPa young modulus and 135% relative cell viability.
dc.language	English
dc.publisher	TAYLOR & FRANCIS AS
dc.relation.ispartof	International Journal of Polymeric Materials and Polymeric Biomaterials
dc.relation.isbasedon	10.1080/00914037.2018.1443930
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	03 Chemical Sciences, 09 Engineering
dc.subject.classification	Polymers
dc.title	Production of the biomimetic small diameter blood vessels for cardiovascular tissue engineering
dc.type	Journal Article
utslib.citation.volume	68
utslib.for	03 Chemical Sciences
utslib.for	09 Engineering
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2020-05-11T04:06:30Z
pubs.issue	5
pubs.publication-status	Accepted
pubs.volume	68
utslib.start-page	243
utslib.citation.issue	5

Abstract:

© 2018 Taylor & Francis A novel biomimetic vascular graft scaffolds were produced by electrospinning method with the most superior characteristics to be a proper biomimetic small diameter blood vessel using Polycaprolactone(PCL), Ethyl Cellulose(EC) and Collagen Type-1 were used to create the most convenient synergy of a natural and synthetic polymer to achieve similarity to native small diameter blood vessels. Scanning Electron Microscopy(SEM), Fourier Transform Infrared Spectroscopy(FTIR), Differential Scanning Calorimetry Analysis(DSC), tensile measurement tests, and in-vitro and in-vivo applications were performed. Results indicated significant properties such as having 39.33 nm minimum, 104.98 nm average fiber diameter, 3.2 MPa young modulus and 135% relative cell viability.

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http://hdl.handle.net/10453/140620