Efficacy of Sucrose in Reducing Pain during Immunization among 10- to 18-Month-Old Infants and Young Children: A Randomized Controlled Trial.

Kassab, M; Almomani, B; Nuseir, K; Alhouary, AA

Efficacy of Sucrose in Reducing Pain during Immunization among 10- to 18-Month-Old Infants and Young Children: A Randomized Controlled Trial.

Kassab, M Almomani, B Nuseir, K Alhouary, AA

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Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: Journal of Pediatric Nursing, 2020, 50, pp. e55-e61
Issue Date:: 2020-01

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Field	Value	Language
dc.contributor.author	Kassab, M
dc.contributor.author	Almomani, B
dc.contributor.author	Nuseir, K
dc.contributor.author	Alhouary, AA
dc.date.accessioned	2020-08-17T02:09:35Z
dc.date.available	2019-11-20
dc.date.available	2020-08-17T02:09:35Z
dc.date.issued	2020-01
dc.identifier.citation	Journal of Pediatric Nursing, 2020, 50, pp. e55-e61
dc.identifier.issn	0882-5963
dc.identifier.issn	1532-8449
dc.identifier.uri	http://hdl.handle.net/10453/142139
dc.description.abstract	PURPOSE:Sucrose is recommended to reduce pain associated with vaccination in neonates. However, research results concerning its effectiveness in infants and young children are inconclusive. This study aims to determine the efficacy of sucrose administration in reducing pain during immunization in 10- to 18-month-old infants and young children as assessed by behavioral pain parameters, crying time, and saliva substance (P) concentration. DESIGN AND METHODS:This was a double-blind, randomized controlled trial and included healthy infants and young children undergoing their 10- to 18-month immunization. Behavioral pain outcome was measured during, and shortly after the last injection. The infant's pain was also measured by a salivary test using substance (P), and videotaping of crying time. RESULTS:The study results indicate that, compared with a placebo group, the sucrose group had significantly less pain post-immunization (F (1,129) = 1.72, p = 0.001). Moreover, substance (P) was lower in the intervention group post-immunization, and it could be considered a good predictor of pain reduction associated with immunization. CONCLUSIONS:Sucrose administration during immunization injection helps in reducing pain, which is one of the most critical factors affecting compliance with the immunization schedule. Substance (P) measurement can be used as a predictor of immunization pain level in 10- to 18-month-old infants and young children. PRACTICE IMPLICATIONS:Sucrose is an effective method to reduce needle pain during immunization; therefore, healthcare providers should administer sucrose as a pain relief intervention in the immunization clinical setting.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier
dc.relation.ispartof	Journal of Pediatric Nursing
dc.relation.isbasedon	10.1016/j.pedn.2019.11.010
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1110 Nursing, 1114 Paediatrics and Reproductive Medicine
dc.subject.classification	Nursing
dc.title	Efficacy of Sucrose in Reducing Pain during Immunization among 10- to 18-Month-Old Infants and Young Children: A Randomized Controlled Trial.
dc.type	Journal Article
utslib.citation.volume	50
utslib.location.activity	United States
utslib.for	1110 Nursing
utslib.for	1114 Paediatrics and Reproductive Medicine
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2020-08-17T02:09:22Z
pubs.publication-status	Published
pubs.volume	50

Abstract:

PURPOSE:Sucrose is recommended to reduce pain associated with vaccination in neonates. However, research results concerning its effectiveness in infants and young children are inconclusive. This study aims to determine the efficacy of sucrose administration in reducing pain during immunization in 10- to 18-month-old infants and young children as assessed by behavioral pain parameters, crying time, and saliva substance (P) concentration. DESIGN AND METHODS:This was a double-blind, randomized controlled trial and included healthy infants and young children undergoing their 10- to 18-month immunization. Behavioral pain outcome was measured during, and shortly after the last injection. The infant's pain was also measured by a salivary test using substance (P), and videotaping of crying time. RESULTS:The study results indicate that, compared with a placebo group, the sucrose group had significantly less pain post-immunization (F (1,129) = 1.72, p = 0.001). Moreover, substance (P) was lower in the intervention group post-immunization, and it could be considered a good predictor of pain reduction associated with immunization. CONCLUSIONS:Sucrose administration during immunization injection helps in reducing pain, which is one of the most critical factors affecting compliance with the immunization schedule. Substance (P) measurement can be used as a predictor of immunization pain level in 10- to 18-month-old infants and young children. PRACTICE IMPLICATIONS:Sucrose is an effective method to reduce needle pain during immunization; therefore, healthcare providers should administer sucrose as a pain relief intervention in the immunization clinical setting.

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http://hdl.handle.net/10453/142139