Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery.

Publisher:
OXFORD UNIV PRESS INC
Publication Type:
Journal Article
Citation:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2020, 58, (3), pp. 500-510
Issue Date:
2020-09
Full metadata record
SUMMARY:Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as 'bioink' have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells.
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