Blood pressure postpartum (BP2) RCT protocol: Follow-up and lifestyle behaviour change strategies in the first 12 months after hypertensive pregnancy.

Henry, A; Arnott, C; Makris, A; Davis, G; Hennessy, A; Beech, A; Pettit, F; Se Homer, C; Craig, ME; Roberts, L; Hyett, J; Chambers, G; Fitzgerald, O; Gow, M; Mann, L; Challis, D; Gale, M; Ruhotas, A; Kirwin, E; Denney-Wilson, E; Brown, M

Blood pressure postpartum (BP2) RCT protocol: Follow-up and lifestyle behaviour change strategies in the first 12 months after hypertensive pregnancy.

Henry, A Arnott, C Makris, A Davis, G Hennessy, A Beech, A Pettit, F Se Homer, C Craig, ME Roberts, L Hyett, J Chambers, G Fitzgerald, O Gow, M Mann, L Challis, D Gale, M Ruhotas, A Kirwin, E Denney-Wilson, E

Brown, M

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Publisher:: Elsevier BV
Publication Type:: Journal Article
Citation:: Pregnancy hypertension, 2020, 22, pp. 1-6
Issue Date:: 2020-10

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Field	Value	Language
dc.contributor.author	Henry, A
dc.contributor.author	Arnott, C
dc.contributor.author	Makris, A
dc.contributor.author	Davis, G
dc.contributor.author	Hennessy, A
dc.contributor.author	Beech, A
dc.contributor.author	Pettit, F
dc.contributor.author	Se Homer, C
dc.contributor.author	Craig, ME
dc.contributor.author	Roberts, L
dc.contributor.author	Hyett, J
dc.contributor.author	Chambers, G
dc.contributor.author	Fitzgerald, O
dc.contributor.author	Gow, M
dc.contributor.author	Mann, L
dc.contributor.author	Challis, D
dc.contributor.author	Gale, M
dc.contributor.author	Ruhotas, A
dc.contributor.author	Kirwin, E
dc.contributor.author	Denney-Wilson, E https://orcid.org/0000-0001-9879-4969
dc.contributor.author	Brown, M
dc.date.accessioned	2020-12-09T03:44:16Z
dc.date.available	2020-07-02
dc.date.available	2020-12-09T03:44:16Z
dc.date.issued	2020-10
dc.identifier.citation	Pregnancy hypertension, 2020, 22, pp. 1-6
dc.identifier.issn	2210-7789
dc.identifier.issn	2210-7797
dc.identifier.uri	http://hdl.handle.net/10453/144583
dc.description.abstract	OBJECTIVES:Women who had hypertensive disorders of pregnancy (HDP) are twice as likely to experience maternal cardiovascular disease later in life. The primary aim of this study (BP2) is to compare outcomes of 3 different management strategies, including lifestyle behaviour change (LBC), in the first 12 months postpartum in women who had HDP in their preceding pregnancy. Secondary aims include assessing the effects on other cardiometabolic parameters. STUDY DESIGN:Three-arm multicentre randomised trial in metropolitan Australian hospitals, (registration: ACTRN12618002004246) target sample size 480. Participants are randomised to one of three groups: 1) Optimised usual care: information package and family doctor follow-up 6 months postpartum 2) Brief intervention: information package as per group 1, plus assessment and brief LBC counselling at a specialised clinic with an obstetric physician and dietitian 6 months postpartum 3) Extended intervention: as per group 2 plus enrolment into a 6 month telephone-based LBC program from 6 to 12 months postpartum. All women have an outcome assessment at 12 months. MAIN OUTCOME MEASURES:Primary outcomes: (a) BP change or (b) weight change and/or waist circumference change. SECONDARY OUTCOMES:maternal health-related quality of life, engagement and retention in LBC program, biochemical markers, vascular function testing, infant weight trajectory, incremental cost-effectiveness ratios. The study is powered to detect a 4 mmHg difference in systolic BP between groups, or a 4 kg weight loss difference/2cm waist circumference change. CONCLUSIONS:BP2 will provide evidence regarding the feasibility and effectiveness of postpartum LBC interventions and structured clinical follow-up in improving cardiovascular health markers after HDP.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier BV
dc.relation	http://purl.org/au-research/grants/nhmrc/GNT1137745
dc.relation.ispartof	Pregnancy hypertension
dc.relation.isbasedon	10.1016/j.preghy.2020.07.001
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	1114 Paediatrics and Reproductive Medicine
dc.title	Blood pressure postpartum (BP2) RCT protocol: Follow-up and lifestyle behaviour change strategies in the first 12 months after hypertensive pregnancy.
dc.type	Journal Article
utslib.citation.volume	22
utslib.location.activity	Netherlands
utslib.for	1114 Paediatrics and Reproductive Medicine
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Strength - WHO CC
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2020-12-09T03:44:10Z
pubs.publication-status	Published
pubs.volume	22

Abstract:

OBJECTIVES:Women who had hypertensive disorders of pregnancy (HDP) are twice as likely to experience maternal cardiovascular disease later in life. The primary aim of this study (BP2) is to compare outcomes of 3 different management strategies, including lifestyle behaviour change (LBC), in the first 12 months postpartum in women who had HDP in their preceding pregnancy. Secondary aims include assessing the effects on other cardiometabolic parameters. STUDY DESIGN:Three-arm multicentre randomised trial in metropolitan Australian hospitals, (registration: ACTRN12618002004246) target sample size 480. Participants are randomised to one of three groups: 1) Optimised usual care: information package and family doctor follow-up 6 months postpartum 2) Brief intervention: information package as per group 1, plus assessment and brief LBC counselling at a specialised clinic with an obstetric physician and dietitian 6 months postpartum 3) Extended intervention: as per group 2 plus enrolment into a 6 month telephone-based LBC program from 6 to 12 months postpartum. All women have an outcome assessment at 12 months. MAIN OUTCOME MEASURES:Primary outcomes: (a) BP change or (b) weight change and/or waist circumference change. SECONDARY OUTCOMES:maternal health-related quality of life, engagement and retention in LBC program, biochemical markers, vascular function testing, infant weight trajectory, incremental cost-effectiveness ratios. The study is powered to detect a 4 mmHg difference in systolic BP between groups, or a 4 kg weight loss difference/2cm waist circumference change. CONCLUSIONS:BP2 will provide evidence regarding the feasibility and effectiveness of postpartum LBC interventions and structured clinical follow-up in improving cardiovascular health markers after HDP.

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http://hdl.handle.net/10453/144583