Evaluation of salvia miltiorrhiza radix (Danshen) in the treatment of chronic kidney disease: A literature review

Carè, J

Evaluation of salvia miltiorrhiza radix (Danshen) in the treatment of chronic kidney disease: A literature review

Carè, J

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Publication Type:: Journal Article
Citation:: Australian Journal of Herbal Medicine, 2017, 29, (3), pp. 96-106
Issue Date:: 2017-01-01

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Field	Value	Language
dc.contributor.author	Carè, J
dc.date.accessioned	2021-02-24T06:33:29Z
dc.date.available	2021-02-24T06:33:29Z
dc.date.issued	2017-01-01
dc.identifier.citation	Australian Journal of Herbal Medicine, 2017, 29, (3), pp. 96-106
dc.identifier.issn	2200-3886
dc.identifier.uri	http://hdl.handle.net/10453/146396
dc.description.abstract	© NHAA 2017. Chronic kidney disease (CKD) is a significant global public health issue with few treatments currently available that effectively reverse the disease or prevent its progression. Diabetes mellitus, cardiovascular disease, hypertension and acute kidney disease are the major contributors to CKD. These co-morbidities cause the destruction of glomeruli resulting in blood flow changes, activation of the renin-angiotensin-aldosterone system, systemic hypertension, proteinuria, inflammation and oxidative stress. Pharmaceutical interventions, including angiotensin converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers and diuretics, are used as mono- or combination therapies to achieve blood pressure control and improve the condition. However, combinations of pharmaceuticals increase the risk of adverse events and in many patients does not prevent progression to renal failure. Salvia miltiorrhiza radix (Danshen) is a traditional Chinese herb that shows considerable potential in ameliorating the effects of CKD. A computer-based search of Cinahl, The Cochrane Library, Embase, Medline and TRIP databases was performed to appraise the scientific literature on this herb. While there is little evidence for the use of Danshen in CKD and no human studies have been located, this review provides a summary of the research to date that may reveal a novel treatment for this disease.
dc.language	en
dc.relation.ispartof	Australian Journal of Herbal Medicine
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1104 Complementary and Alternative Medicine
dc.title	Evaluation of salvia miltiorrhiza radix (Danshen) in the treatment of chronic kidney disease: A literature review
dc.type	Journal Article
utslib.citation.volume	29
utslib.for	1104 Complementary and Alternative Medicine
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access	*
dc.date.updated	2021-02-24T06:33:19Z
pubs.issue	3
pubs.publication-status	Published
pubs.volume	29
utslib.citation.issue	3

Abstract:

© NHAA 2017. Chronic kidney disease (CKD) is a significant global public health issue with few treatments currently available that effectively reverse the disease or prevent its progression. Diabetes mellitus, cardiovascular disease, hypertension and acute kidney disease are the major contributors to CKD. These co-morbidities cause the destruction of glomeruli resulting in blood flow changes, activation of the renin-angiotensin-aldosterone system, systemic hypertension, proteinuria, inflammation and oxidative stress. Pharmaceutical interventions, including angiotensin converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers and diuretics, are used as mono- or combination therapies to achieve blood pressure control and improve the condition. However, combinations of pharmaceuticals increase the risk of adverse events and in many patients does not prevent progression to renal failure. Salvia miltiorrhiza radix (Danshen) is a traditional Chinese herb that shows considerable potential in ameliorating the effects of CKD. A computer-based search of Cinahl, The Cochrane Library, Embase, Medline and TRIP databases was performed to appraise the scientific literature on this herb. While there is little evidence for the use of Danshen in CKD and no human studies have been located, this review provides a summary of the research to date that may reveal a novel treatment for this disease.

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http://hdl.handle.net/10453/146396