Application of microfluidic technology in cancer research and therapy.

Azadi, S; Aboulkheyr Es, H; Kulasinghe, A; Bordhan, P; Ebrahimi Warkiani, M

Application of microfluidic technology in cancer research and therapy.

Azadi, S Aboulkheyr Es, H Kulasinghe, A Bordhan, P Ebrahimi Warkiani, M

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Publisher:: Elsevier
Publication Type:: Chapter
Citation:: Advances in Clinical Chemistry, 2020, 99, pp. 193-235
Issue Date:: 2020-01

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Field	Value	Language
dc.contributor.author	Azadi, S
dc.contributor.author	Aboulkheyr Es, H
dc.contributor.author	Kulasinghe, A
dc.contributor.author	Bordhan, P
dc.contributor.author	Ebrahimi Warkiani, M https://orcid.org/0000-0002-4184-1944
dc.date.accessioned	2021-03-16T21:39:41Z
dc.date.available	2021-03-16T21:39:41Z
dc.date.issued	2020-01
dc.identifier.citation	Advances in Clinical Chemistry, 2020, 99, pp. 193-235
dc.identifier.isbn	9780128215609
dc.identifier.uri	http://hdl.handle.net/10453/147253
dc.description.abstract	Cancer is a heterogeneous disease that requires a multimodal approach to diagnose, manage and treat. A better understanding of the disease biology can lead to identification of novel diagnostic/prognostic biomarkers and the discovery of the novel therapeutics with the goal of improving patient outcomes. Employing advanced technologies can facilitate this, enabling better diagnostic and treatment for cancer patients. In this regard, microfluidic technology has emerged as a promising tool in the studies of cancer, including single cancer cell analysis, modeling angiogenesis and metastasis, drug screening and liquid biopsy. Microfluidic technologies have opened new ways to study tumors in the preclinical and clinical settings. In this chapter, we highlight novel application of this technology in area of fundamental, translational and clinical cancer research.
dc.format	Print-Electronic
dc.language	en
dc.publisher	Elsevier
dc.relation.ispartof	Advances in Clinical Chemistry
dc.relation.isbasedon	10.1016/bs.acc.2020.02.012
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1103 Clinical Sciences
dc.subject.classification	General Clinical Medicine
dc.title	Application of microfluidic technology in cancer research and therapy.
dc.type	Chapter
utslib.citation.volume	99
utslib.for	1103 Clinical Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	closed_access	*
dc.date.updated	2021-03-16T21:39:38Z
pubs.publication-status	Published
pubs.volume	99

Abstract:

Cancer is a heterogeneous disease that requires a multimodal approach to diagnose, manage and treat. A better understanding of the disease biology can lead to identification of novel diagnostic/prognostic biomarkers and the discovery of the novel therapeutics with the goal of improving patient outcomes. Employing advanced technologies can facilitate this, enabling better diagnostic and treatment for cancer patients. In this regard, microfluidic technology has emerged as a promising tool in the studies of cancer, including single cancer cell analysis, modeling angiogenesis and metastasis, drug screening and liquid biopsy. Microfluidic technologies have opened new ways to study tumors in the preclinical and clinical settings. In this chapter, we highlight novel application of this technology in area of fundamental, translational and clinical cancer research.

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http://hdl.handle.net/10453/147253