SARS CoV-2 aerosol: How far it can travel to the lower airways?

Islam, MS; Larpruenrudee, P; Paul, AR; Paul, G; Gemci, T; Gu, Y; Saha, SC

SARS CoV-2 aerosol: How far it can travel to the lower airways?

Islam, MS Larpruenrudee, P Paul, AR Paul, G Gemci, T Gu, Y Saha, SC

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Publisher:: AMER INST PHYSICS
Publication Type:: Journal Article
Citation:: Physics of Fluids, 2021, 33, (6), pp. 061903
Issue Date:: 2021-06-01

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Field	Value	Language
dc.contributor.author	Islam, MS
dc.contributor.author	Larpruenrudee, P
dc.contributor.author	Paul, AR
dc.contributor.author	Paul, G
dc.contributor.author	Gemci, T
dc.contributor.author	Gu, Y
dc.contributor.author	Saha, SC
dc.date.accessioned	2021-08-18T12:26:21Z
dc.date.available	2021-05-13
dc.date.available	2021-08-18T12:26:21Z
dc.date.issued	2021-06-01
dc.identifier.citation	Physics of Fluids, 2021, 33, (6), pp. 061903
dc.identifier.issn	1070-6631
dc.identifier.issn	1089-7666
dc.identifier.uri	http://hdl.handle.net/10453/150157
dc.description.abstract	The recent outbreak of the SARS CoV-2 virus has had a significant effect on human respiratory health around the world. The contagious disease infected a large proportion of the world population, resulting in long-term health issues and an excessive mortality rate. The SARS CoV-2 virus can spread as small aerosols and enters the respiratory systems through the oral (nose or mouth) airway. The SARS CoV-2 particle transport to the mouth-throat and upper airways is analyzed by the available literature. Due to the tiny size, the virus can travel to the terminal airways of the respiratory system and form a severe health hazard. There is a gap in the understanding of the SARS CoV-2 particle transport to the terminal airways. The present study investigated the SARS CoV-2 virus particle transport and deposition to the terminal airways in a complex 17-generation lung model. This first-ever study demonstrates how far SARS CoV-2 particles can travel in the respiratory system. ANSYS Fluent solver was used to simulate the virus particle transport during sleep and light and heavy activity conditions. Numerical results demonstrate that a higher percentage of the virus particles are trapped at the upper airways when sleeping and in a light activity condition. More virus particles have lung contact in the right lung than the left lung. A comprehensive lobe specific deposition and deposition concentration study was performed. The results of this study provide a precise knowledge of the SARs CoV-2 particle transport to the lower branches and could help the lung health risk assessment system.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	AMER INST PHYSICS
dc.relation.ispartof	Physics of Fluids
dc.relation.isbasedon	10.1063/5.0053351
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	01 Mathematical Sciences, 02 Physical Sciences, 09 Engineering
dc.subject.classification	Fluids & Plasmas
dc.title	SARS CoV-2 aerosol: How far it can travel to the lower airways?
dc.type	Journal Article
utslib.citation.volume	33
utslib.location.activity	United States
utslib.for	01 Mathematical Sciences
utslib.for	02 Physical Sciences
utslib.for	09 Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Mechanical and Mechatronic Engineering
utslib.copyright.status	open_access	*
dc.date.updated	2021-08-18T12:26:19Z
pubs.issue	6
pubs.publication-status	Published
pubs.volume	33
utslib.citation.issue	6

Abstract:

The recent outbreak of the SARS CoV-2 virus has had a significant effect on human respiratory health around the world. The contagious disease infected a large proportion of the world population, resulting in long-term health issues and an excessive mortality rate. The SARS CoV-2 virus can spread as small aerosols and enters the respiratory systems through the oral (nose or mouth) airway. The SARS CoV-2 particle transport to the mouth-throat and upper airways is analyzed by the available literature. Due to the tiny size, the virus can travel to the terminal airways of the respiratory system and form a severe health hazard. There is a gap in the understanding of the SARS CoV-2 particle transport to the terminal airways. The present study investigated the SARS CoV-2 virus particle transport and deposition to the terminal airways in a complex 17-generation lung model. This first-ever study demonstrates how far SARS CoV-2 particles can travel in the respiratory system. ANSYS Fluent solver was used to simulate the virus particle transport during sleep and light and heavy activity conditions. Numerical results demonstrate that a higher percentage of the virus particles are trapped at the upper airways when sleeping and in a light activity condition. More virus particles have lung contact in the right lung than the left lung. A comprehensive lobe specific deposition and deposition concentration study was performed. The results of this study provide a precise knowledge of the SARs CoV-2 particle transport to the lower branches and could help the lung health risk assessment system.

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http://hdl.handle.net/10453/150157