Interventions to Enhance Medication Safety in Residential Aged-care Settings: An Umbrella Review.

Alruthea, S; Bowman, P; Tariq, A; Hinchcliff, R

Interventions to Enhance Medication Safety in Residential Aged-care Settings: An Umbrella Review.

Alruthea, S Bowman, P Tariq, A Hinchcliff, R

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Publisher:: Wiley
Publication Type:: Journal Article
Citation:: British journal of clinical pharmacology, 2021
Issue Date:: 2021-10-15

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Field	Value	Language
dc.contributor.author	Alruthea, S
dc.contributor.author	Bowman, P
dc.contributor.author	Tariq, A
dc.contributor.author	Hinchcliff, R https://orcid.org/0000-0001-9920-4211
dc.date.accessioned	2022-01-04T00:27:49Z
dc.date.available	2021-10-07
dc.date.available	2022-01-04T00:27:49Z
dc.date.issued	2021-10-15
dc.identifier.citation	British journal of clinical pharmacology, 2021
dc.identifier.issn	0306-5251
dc.identifier.issn	1365-2125
dc.identifier.uri	http://hdl.handle.net/10453/152622
dc.description.abstract	<h4>Aim</h4>To conduct a systematic synthesis of existing evidence reviews on interventions to enhance medication safety in residential aged-care settings (RACS) to establish and compare their effectiveness.<h4>Method</h4>This umbrella review included examination of meta-analyses, scoping and systematic reviews. Four electronic databases were examined for eligible reviews. Two authors critically appraised those meeting the inclusion criteria using the Joanna Briggs Institute Critical Appraisal Instrument.<h4>Results</h4>Fifteen reviews covering 171 unique, primary studies were included. Of the variety of interventions identified in the literature, five main categories of interventions were commonly reported to be effective in promoting medication safety in RACS (medication review, staff education, multidisciplinary team meetings, computerised clinical decision support systems and miscellaneous). Most reviews showed mixed evidence to support intervention effectiveness due to the significant heterogeneity between studies in their sites, sample sizes and intervention periods. In all intervention categories, pharmacists' collaboration was most beneficial, showing definitive evidence for improving medication safety and quality of prescribing in RACS. Eight reviews recommended multicomponent interventions, particularly medication reviews and staff education, but specific details were infrequently provided. Only five reviews presented insights into implementation facilitators and barriers, while the sustainability of interventions was only discussed in one review.<h4>Conclusion</h4>There is strong evidence to support the four main categories of interventions identified. However, limited details are available regarding the most appropriate design and implementation of multicomponent interventions and the sustainability of all interventions, thus solid recommendations cannot be made. Future research in this field should focus on producing theoretically informed, methodologically robust, original research, particularly regarding the design, implementation and sustainability of multicomponent interventions, which appears the most promising approach.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Wiley
dc.relation.ispartof	British journal of clinical pharmacology
dc.relation.isbasedon	10.1111/bcp.15109
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences
dc.subject.classification	Pharmacology & Pharmacy
dc.title	Interventions to Enhance Medication Safety in Residential Aged-care Settings: An Umbrella Review.
dc.type	Journal Article
utslib.location.activity	England
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access	*
dc.date.updated	2022-01-04T00:27:48Z
pubs.publication-status	Published

Abstract:

Aim

To conduct a systematic synthesis of existing evidence reviews on interventions to enhance medication safety in residential aged-care settings (RACS) to establish and compare their effectiveness.

Method

This umbrella review included examination of meta-analyses, scoping and systematic reviews. Four electronic databases were examined for eligible reviews. Two authors critically appraised those meeting the inclusion criteria using the Joanna Briggs Institute Critical Appraisal Instrument.

Results

Fifteen reviews covering 171 unique, primary studies were included. Of the variety of interventions identified in the literature, five main categories of interventions were commonly reported to be effective in promoting medication safety in RACS (medication review, staff education, multidisciplinary team meetings, computerised clinical decision support systems and miscellaneous). Most reviews showed mixed evidence to support intervention effectiveness due to the significant heterogeneity between studies in their sites, sample sizes and intervention periods. In all intervention categories, pharmacists' collaboration was most beneficial, showing definitive evidence for improving medication safety and quality of prescribing in RACS. Eight reviews recommended multicomponent interventions, particularly medication reviews and staff education, but specific details were infrequently provided. Only five reviews presented insights into implementation facilitators and barriers, while the sustainability of interventions was only discussed in one review.

Conclusion

There is strong evidence to support the four main categories of interventions identified. However, limited details are available regarding the most appropriate design and implementation of multicomponent interventions and the sustainability of all interventions, thus solid recommendations cannot be made. Future research in this field should focus on producing theoretically informed, methodologically robust, original research, particularly regarding the design, implementation and sustainability of multicomponent interventions, which appears the most promising approach.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/152622