Advances of microfluidic technology in reproductive biology.

Nikshad, A; Aghlmandi, A; Safaralizadeh, R; Aghebati-Maleki, L; Warkiani, ME; Khiavi, FM; Yousefi, M

Advances of microfluidic technology in reproductive biology.

Nikshad, A Aghlmandi, A Safaralizadeh, R Aghebati-Maleki, L Warkiani, ME Khiavi, FM Yousefi, M

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Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: Life Sciences, 2021, 265, pp. 1-8
Issue Date:: 2021-01-15

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Field	Value	Language
dc.contributor.author	Nikshad, A
dc.contributor.author	Aghlmandi, A
dc.contributor.author	Safaralizadeh, R
dc.contributor.author	Aghebati-Maleki, L
dc.contributor.author	Warkiani, ME
dc.contributor.author	Khiavi, FM
dc.contributor.author	Yousefi, M
dc.date.accessioned	2022-03-08T03:52:20Z
dc.date.available	2020-11-13
dc.date.available	2022-03-08T03:52:20Z
dc.date.issued	2021-01-15
dc.identifier.citation	Life Sciences, 2021, 265, pp. 1-8
dc.identifier.issn	0024-3205
dc.identifier.issn	1879-0631
dc.identifier.uri	http://hdl.handle.net/10453/155053
dc.description.abstract	According to World Health Organization (WHO) reports about 70 million couples suffer from infertility all over the world. A lot of research groups are working on this issue and have made therapeutic approaches by integrating biology, medicine, genetics, chemistry, psychology, mechanic, and many other branches of science. However, these methods have their own pros and cons. Assisted Reproductive Technologies (ART) has appeared to solve infertility problems. In Vitro Fertilization (IVF), Intracytoplasmic Sperm Injection (ICSI), Intrauterine Insemination (IUI) are the most common and conventional technologies in this regard. There are at least two characteristics of microfluidics, mechanical and biochemical, which can be influential in the field of mammalian gamete and preimplantation embryo biology. These microfluidic characteristics can assist in basic biological studies on sperm, oocyte and preimplantation embryo structure, function and environment. Using microfluidics in sorting sperm, conducting different steps of oocyte selection and preparation, and transferring embryo by passing sub-microliter fluid through microchannels results in low cost and short time. The size and shape of microchannels and the volume of used fluid differs from non-human cells to human cells. The most progressions have been seen in animal models. Results suggest that microfluidic systems will lead to improved efficiencies in assisted reproduction.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier
dc.relation.ispartof	Life Sciences
dc.relation.isbasedon	10.1016/j.lfs.2020.118767
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0601 Biochemistry and Cell Biology, 1115 Pharmacology and Pharmaceutical Sciences
dc.subject.classification	Pharmacology & Pharmacy
dc.subject.mesh	Animals
dc.subject.mesh	Cryopreservation
dc.subject.mesh	Embryo Culture Techniques
dc.subject.mesh	Female
dc.subject.mesh	Fertilization in Vitro
dc.subject.mesh	Humans
dc.subject.mesh	Lab-On-A-Chip Devices
dc.subject.mesh	Male
dc.subject.mesh	Microfluidic Analytical Techniques
dc.subject.mesh	Microfluidics
dc.subject.mesh	Reproductive Techniques, Assisted
dc.subject.mesh	Spermatozoa
dc.subject.mesh	Animals
dc.subject.mesh	Cryopreservation
dc.subject.mesh	Embryo Culture Techniques
dc.subject.mesh	Female
dc.subject.mesh	Fertilization in Vitro
dc.subject.mesh	Humans
dc.subject.mesh	Lab-On-A-Chip Devices
dc.subject.mesh	Male
dc.subject.mesh	Microfluidic Analytical Techniques
dc.subject.mesh	Microfluidics
dc.subject.mesh	Reproductive Techniques, Assisted
dc.subject.mesh	Spermatozoa
dc.subject.mesh	Spermatozoa
dc.subject.mesh	Animals
dc.subject.mesh	Humans
dc.subject.mesh	Cryopreservation
dc.subject.mesh	Reproductive Techniques, Assisted
dc.subject.mesh	Fertilization in Vitro
dc.subject.mesh	Microfluidic Analytical Techniques
dc.subject.mesh	Embryo Culture Techniques
dc.subject.mesh	Microfluidics
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Lab-On-A-Chip Devices
dc.title	Advances of microfluidic technology in reproductive biology.
dc.type	Journal Article
utslib.citation.volume	265
utslib.location.activity	Netherlands
utslib.for	0601 Biochemistry and Cell Biology
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
pubs.organisational-group	/University of Technology Sydney/Centre for Health Technologies (CHT)
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2022-03-08T03:52:19Z
pubs.publication-status	Published
pubs.volume	265

Abstract:

According to World Health Organization (WHO) reports about 70 million couples suffer from infertility all over the world. A lot of research groups are working on this issue and have made therapeutic approaches by integrating biology, medicine, genetics, chemistry, psychology, mechanic, and many other branches of science. However, these methods have their own pros and cons. Assisted Reproductive Technologies (ART) has appeared to solve infertility problems. In Vitro Fertilization (IVF), Intracytoplasmic Sperm Injection (ICSI), Intrauterine Insemination (IUI) are the most common and conventional technologies in this regard. There are at least two characteristics of microfluidics, mechanical and biochemical, which can be influential in the field of mammalian gamete and preimplantation embryo biology. These microfluidic characteristics can assist in basic biological studies on sperm, oocyte and preimplantation embryo structure, function and environment. Using microfluidics in sorting sperm, conducting different steps of oocyte selection and preparation, and transferring embryo by passing sub-microliter fluid through microchannels results in low cost and short time. The size and shape of microchannels and the volume of used fluid differs from non-human cells to human cells. The most progressions have been seen in animal models. Results suggest that microfluidic systems will lead to improved efficiencies in assisted reproduction.

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http://hdl.handle.net/10453/155053