Alarms and Their Outcomes in Left Ventricular Assist Device Patients.

Lim, ZZ; Robson, D; Muthiah, K; Jansz, P; Macdonald, PS; Hayward, CS

Alarms and Their Outcomes in Left Ventricular Assist Device Patients.

Lim, ZZ Robson, D Muthiah, K Jansz, P Macdonald, PS Hayward, CS

Permalink

Publisher:: LIPPINCOTT WILLIAMS & WILKINS
Publication Type:: Journal Article
Citation:: ASAIO J, 2021, 67, (12), pp. 1284-1293
Issue Date:: 2021-12-01

Closed Access

	Filename	Description	Size
	18788130_6958152780005671.pdf	Published version	699.72 kB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Lim, ZZ
dc.contributor.author	Robson, D
dc.contributor.author	Muthiah, K
dc.contributor.author	Jansz, P
dc.contributor.author	Macdonald, PS
dc.contributor.author	Hayward, CS
dc.date.accessioned	2022-04-11T19:49:42Z
dc.date.available	2022-04-11T19:49:42Z
dc.date.issued	2021-12-01
dc.identifier.citation	ASAIO J, 2021, 67, (12), pp. 1284-1293
dc.identifier.issn	1058-2916
dc.identifier.issn	1538-943X
dc.identifier.uri	http://hdl.handle.net/10453/156081
dc.description.abstract	Low flow and suction alarms are provided to alert caregivers of changes in left ventricular assist device pump function but may be reset in clinical practice. We investigated the incidence and underlying causes of these alarms as well as their prognostic significance. HeartWare ventricular assist device patients (n = 113) were divided into quartiles based on their frequency of low flow and suction alarms. Survival and adverse events (thrombus, stroke, bleeding, and right heart failure) were compared between quartiles. Low flow alarms peaked in the first few months of pump support before dropping down to near negligible levels. Suction alarm frequency remained relatively constant throughout pump support. Although pump speeds (p < 0.001) and flow (p = 0.01) decreased over time, there was an increase in suction alarm frequency (p = 0.018), with no changes in low flow alarms. Patients with smaller body size (p = 0.016) and lower pump flows (p = 0.008) had higher frequencies of low flow alarms on multiple regression (p < 0.001). Patients with the highest low flow alarm frequency demonstrated poorer survival (p = 0.026). There was no relationship between suction alarm frequency and survival. There was also no relationship between either low flow or suction alarm frequency with strokes, gastrointestinal bleeds, pump thrombus, or right ventricular failure. Duration of alarm and intervention in response to the alarm was not assessed in this study. Further studies examining alarm duration and responses may inform future pump alarm algorithms.
dc.format	Print
dc.language	eng
dc.publisher	LIPPINCOTT WILLIAMS & WILKINS
dc.relation.ispartof	ASAIO J
dc.relation.isbasedon	10.1097/MAT.0000000000001483
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0903 Biomedical Engineering
dc.subject.classification	Biomedical Engineering
dc.subject.mesh	Gastrointestinal Hemorrhage
dc.subject.mesh	Heart Failure
dc.subject.mesh	Heart-Assist Devices
dc.subject.mesh	Humans
dc.subject.mesh	Stroke
dc.subject.mesh	Thrombosis
dc.title	Alarms and Their Outcomes in Left Ventricular Assist Device Patients.
dc.type	Journal Article
utslib.citation.volume	67
utslib.location.activity	United States
utslib.for	0903 Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access	*
dc.date.updated	2022-04-11T19:49:41Z
pubs.issue	12
pubs.publication-status	Published
pubs.volume	67
utslib.citation.issue	12

Abstract:

Low flow and suction alarms are provided to alert caregivers of changes in left ventricular assist device pump function but may be reset in clinical practice. We investigated the incidence and underlying causes of these alarms as well as their prognostic significance. HeartWare ventricular assist device patients (n = 113) were divided into quartiles based on their frequency of low flow and suction alarms. Survival and adverse events (thrombus, stroke, bleeding, and right heart failure) were compared between quartiles. Low flow alarms peaked in the first few months of pump support before dropping down to near negligible levels. Suction alarm frequency remained relatively constant throughout pump support. Although pump speeds (p < 0.001) and flow (p = 0.01) decreased over time, there was an increase in suction alarm frequency (p = 0.018), with no changes in low flow alarms. Patients with smaller body size (p = 0.016) and lower pump flows (p = 0.008) had higher frequencies of low flow alarms on multiple regression (p < 0.001). Patients with the highest low flow alarm frequency demonstrated poorer survival (p = 0.026). There was no relationship between suction alarm frequency and survival. There was also no relationship between either low flow or suction alarm frequency with strokes, gastrointestinal bleeds, pump thrombus, or right ventricular failure. Duration of alarm and intervention in response to the alarm was not assessed in this study. Further studies examining alarm duration and responses may inform future pump alarm algorithms.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/156081