Determination of Factors Driving the Genome Editing Field in the CRISPR Era Using Bibliometrics.

Huang, Y; Zhang, Y; Wu, M; Porter, A; Barrangou, R

Determination of Factors Driving the Genome Editing Field in the CRISPR Era Using Bibliometrics.

Huang, Y Zhang, Y

Wu, M

Porter, A Barrangou, R

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Publisher:: Mary Ann Liebert Inc
Publication Type:: Journal Article
Citation:: CRISPR J, 2021, 4, (5), pp. 728-738
Issue Date:: 2021-10

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Field	Value	Language
dc.contributor.author	Huang, Y
dc.contributor.author	Zhang, Y https://orcid.org/0000-0002-7731-0301
dc.contributor.author	Wu, M https://orcid.org/0000-0003-3956-7808
dc.contributor.author	Porter, A
dc.contributor.author	Barrangou, R
dc.date.accessioned	2022-06-09T04:12:41Z
dc.date.available	2022-06-09T04:12:41Z
dc.date.issued	2021-10
dc.identifier.citation	CRISPR J, 2021, 4, (5), pp. 728-738
dc.identifier.issn	2573-1599
dc.identifier.issn	2573-1602
dc.identifier.uri	http://hdl.handle.net/10453/158038
dc.description.abstract	Over the past two decades, the discovery of CRISPR-Cas immune systems and the repurposing of their effector nucleases as biotechnological tools have revolutionized genome editing. The corresponding work has been captured by 90,000 authors representing 7,600 affiliations in 126 countries, who have published more than 19,000 papers spanning medicine, agriculture, and biotechnology. Here, we use tech mining and an integrated bibliometric and networks framework to investigate the CRISPR literature over three time periods. The analysis identified seminal papers, leading authors, influential journals, and rising applications and topics interconnected through collaborative networks. A core set of foundational topics gave rise to diverging avenues of research and applications, reflecting a bona fide disruptive emerging technology. This analysis illustrates how bibliometrics can identify key factors, decipher rising trends, and untangle emerging applications and technologies that dynamically shape a morphing field, and provides insights into the trajectory of genome editing.
dc.format	Print
dc.language	eng
dc.publisher	Mary Ann Liebert Inc
dc.relation	http://purl.org/au-research/grants/arc/DE190100994
dc.relation.ispartof	CRISPR J
dc.relation.isbasedon	10.1089/crispr.2021.0001
dc.rights	info:eu-repo/semantics/openAccess
dc.subject.mesh	Animals
dc.subject.mesh	Bibliometrics
dc.subject.mesh	CRISPR-Cas Systems
dc.subject.mesh	Gene Editing
dc.subject.mesh	Humans
dc.subject.mesh	Animals
dc.subject.mesh	Humans
dc.subject.mesh	Bibliometrics
dc.subject.mesh	CRISPR-Cas Systems
dc.subject.mesh	Gene Editing
dc.title	Determination of Factors Driving the Genome Editing Field in the CRISPR Era Using Bibliometrics.
dc.type	Journal Article
utslib.citation.volume	4
utslib.location.activity	United States
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - AAII - Australian Artificial Intelligence Institute
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Computer Science
utslib.copyright.status	open_access	*
dc.date.updated	2022-06-09T04:12:31Z
pubs.issue	5
pubs.publication-status	Published
pubs.volume	4
utslib.citation.issue	5

Abstract:

Over the past two decades, the discovery of CRISPR-Cas immune systems and the repurposing of their effector nucleases as biotechnological tools have revolutionized genome editing. The corresponding work has been captured by 90,000 authors representing 7,600 affiliations in 126 countries, who have published more than 19,000 papers spanning medicine, agriculture, and biotechnology. Here, we use tech mining and an integrated bibliometric and networks framework to investigate the CRISPR literature over three time periods. The analysis identified seminal papers, leading authors, influential journals, and rising applications and topics interconnected through collaborative networks. A core set of foundational topics gave rise to diverging avenues of research and applications, reflecting a bona fide disruptive emerging technology. This analysis illustrates how bibliometrics can identify key factors, decipher rising trends, and untangle emerging applications and technologies that dynamically shape a morphing field, and provides insights into the trajectory of genome editing.

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http://hdl.handle.net/10453/158038