Predicting 10-year mortality in older adults using VO<sub>2</sub>max, oxygen uptake efficiency slope and frailty class.
- Publisher:
- Oxford University Press
- Publication Type:
- Journal Article
- Citation:
- European Journal of Preventive Cardiology, 2021, 28, (10), pp. 1148-1151
- Issue Date:
- 2021-01-01
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Maximal oxygen uptake (VO2max) is the gold-standard cardiorespiratory fitness (CRF) measure in different settings, including pre-operative heart transplant evaluation.1 Achieving VO2max requires full exertion, which may be limited by frailty and pre-frailty in older adults. Importantly, pre-frailty and frailty are associated with adverse clinical outcomes.2 Whether serial measurements of VO2 and log10-transformed minute ventilation (VE) calculated as a ratio termed ‘oxygen uptake efficiency slope’ (OUES)3 is useful in older adults with or without frailty and pre-frailty remains unexplored.
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