Childhood Stress and Adversity is Associated with Late-Life Dementia in Aboriginal Australians.

Radford, K; Delbaere, K; Draper, B; Mack, HA; Daylight, G; Cumming, R; Chalkley, S; Minogue, C; Broe, GA

Childhood Stress and Adversity is Associated with Late-Life Dementia in Aboriginal Australians.

Radford, K Delbaere, K Draper, B Mack, HA Daylight, G Cumming, R Chalkley, S Minogue, C Broe, GA

Permalink

Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: American Journal of Geriatric Psychiatry, 2017, 25, (10), pp. 1097-1106
Issue Date:: 2017-10

Closed Access

	Filename	Description	Size
	19248790_8260385200005671.pdf		209.9 kB		View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Radford, K
dc.contributor.author	Delbaere, K
dc.contributor.author	Draper, B
dc.contributor.author	Mack, HA
dc.contributor.author	Daylight, G
dc.contributor.author	Cumming, R
dc.contributor.author	Chalkley, S
dc.contributor.author	Minogue, C
dc.contributor.author	Broe, GA
dc.date.accessioned	2022-07-07T01:32:42Z
dc.date.available	2017-05-10
dc.date.available	2022-07-07T01:32:42Z
dc.date.issued	2017-10
dc.identifier.citation	American Journal of Geriatric Psychiatry, 2017, 25, (10), pp. 1097-1106
dc.identifier.issn	1064-7481
dc.identifier.issn	1545-7214
dc.identifier.uri	http://hdl.handle.net/10453/158707
dc.description.abstract	OBJECTIVES: High rates of dementia have been observed in Aboriginal Australians. This study aimed to describe childhood stress in older Aboriginal Australians and to examine associations with late-life health and dementia. DESIGN: A cross-sectional study with a representative sample of community-dwelling older Aboriginal Australians. SETTING: Urban and regional communities in New South Wales, Australia. PARTICIPANTS: 336 Aboriginal and/or Torres Strait Islander Australians aged 60-92 years, of whom 296 were included in the current analyses. MEASUREMENTS: Participants completed a life course survey of health, well-being, cognition, and social history including the Childhood Trauma Questionnaire (CTQ), with consensus diagnosis of dementia and Alzheimer disease. RESULTS: CTQ scores ranged from 25-117 (median: 29) and were associated with several adverse childhood indicators including separation from family, poor childhood health, frequent relocation, and growing up in a major city. Controlling for age, higher CTQ scores were associated with depression, anxiety, suicide attempt, dementia diagnosis, and, specifically, Alzheimer disease. The association between CTQ scores and dementia remained significant after controlling for depression and anxiety variables (OR: 1.61, 95% CI: 1.05-2.45). In contrast, there were no significant associations between CTQ scores and smoking, alcohol abuse, diabetes, or cardiovascular risk factors. CONCLUSIONS: Childhood stress appears to have a significant impact on emotional health and dementia for older Aboriginal Australians. The ongoing effects of childhood stress need to be recognized as people grow older, particularly in terms of dementia prevention and care, as well as in populations with greater exposure to childhood adversity, such as Aboriginal Australians.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier
dc.relation.ispartof	American Journal of Geriatric Psychiatry
dc.relation.isbasedon	10.1016/j.jagp.2017.05.008
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1103 Clinical Sciences, 1117 Public Health and Health Services, 1702 Cognitive Sciences
dc.subject.classification	Geriatrics
dc.subject.mesh	Adult Survivors of Child Adverse Events
dc.subject.mesh	Aged
dc.subject.mesh	Aged, 80 and over
dc.subject.mesh	Anxiety Disorders
dc.subject.mesh	Australia
dc.subject.mesh	Comorbidity
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Dementia
dc.subject.mesh	Depressive Disorder
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Middle Aged
dc.subject.mesh	Native Hawaiian or Other Pacific Islander
dc.subject.mesh	Stress Disorders, Post-Traumatic
dc.subject.mesh	Suicide, Attempted
dc.subject.mesh	Adult Survivors of Child Adverse Events
dc.subject.mesh	Aged
dc.subject.mesh	Aged, 80 and over
dc.subject.mesh	Anxiety Disorders
dc.subject.mesh	Australia
dc.subject.mesh	Comorbidity
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Dementia
dc.subject.mesh	Depressive Disorder
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Middle Aged
dc.subject.mesh	Native Hawaiian or Other Pacific Islander
dc.subject.mesh	Stress Disorders, Post-Traumatic
dc.subject.mesh	Suicide, Attempted
dc.subject.mesh	Humans
dc.subject.mesh	Dementia
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Suicide, Attempted
dc.subject.mesh	Anxiety Disorders
dc.subject.mesh	Stress Disorders, Post-Traumatic
dc.subject.mesh	Depressive Disorder
dc.subject.mesh	Comorbidity
dc.subject.mesh	Aged
dc.subject.mesh	Aged, 80 and over
dc.subject.mesh	Middle Aged
dc.subject.mesh	Australia
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Adult Survivors of Child Adverse Events
dc.subject.mesh	Native Hawaiian or Other Pacific Islander
dc.title	Childhood Stress and Adversity is Associated with Late-Life Dementia in Aboriginal Australians.
dc.type	Journal Article
utslib.citation.volume	25
utslib.location.activity	England
utslib.for	1103 Clinical Sciences
utslib.for	1117 Public Health and Health Services
utslib.for	1702 Cognitive Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2022-07-07T01:32:41Z
pubs.issue	10
pubs.publication-status	Published
pubs.volume	25
utslib.citation.issue	10

Abstract:

OBJECTIVES: High rates of dementia have been observed in Aboriginal Australians. This study aimed to describe childhood stress in older Aboriginal Australians and to examine associations with late-life health and dementia. DESIGN: A cross-sectional study with a representative sample of community-dwelling older Aboriginal Australians. SETTING: Urban and regional communities in New South Wales, Australia. PARTICIPANTS: 336 Aboriginal and/or Torres Strait Islander Australians aged 60-92 years, of whom 296 were included in the current analyses. MEASUREMENTS: Participants completed a life course survey of health, well-being, cognition, and social history including the Childhood Trauma Questionnaire (CTQ), with consensus diagnosis of dementia and Alzheimer disease. RESULTS: CTQ scores ranged from 25-117 (median: 29) and were associated with several adverse childhood indicators including separation from family, poor childhood health, frequent relocation, and growing up in a major city. Controlling for age, higher CTQ scores were associated with depression, anxiety, suicide attempt, dementia diagnosis, and, specifically, Alzheimer disease. The association between CTQ scores and dementia remained significant after controlling for depression and anxiety variables (OR: 1.61, 95% CI: 1.05-2.45). In contrast, there were no significant associations between CTQ scores and smoking, alcohol abuse, diabetes, or cardiovascular risk factors. CONCLUSIONS: Childhood stress appears to have a significant impact on emotional health and dementia for older Aboriginal Australians. The ongoing effects of childhood stress need to be recognized as people grow older, particularly in terms of dementia prevention and care, as well as in populations with greater exposure to childhood adversity, such as Aboriginal Australians.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/158707