Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?

Duong, BV; Larpruenrudee, P; Fang, T; Hossain, SI; Saha, SC; Gu, Y; Islam, MS

Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?

Duong, BV Larpruenrudee, P

Fang, T Hossain, SI Saha, SC Gu, Y Islam, MS

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Publisher:: MDPI
Publication Type:: Journal Article
Citation:: Int J Environ Res Public Health, 2022, 19, (8), pp. 4586
Issue Date:: 2022-04-11

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Field	Value	Language
dc.contributor.author	Duong, BV
dc.contributor.author	Larpruenrudee, P https://orcid.org/0000-0002-3413-3667
dc.contributor.author	Fang, T
dc.contributor.author	Hossain, SI
dc.contributor.author	Saha, SC
dc.contributor.author	Gu, Y
dc.contributor.author	Islam, MS
dc.date.accessioned	2022-08-05T04:05:33Z
dc.date.available	2022-04-07
dc.date.available	2022-08-05T04:05:33Z
dc.date.issued	2022-04-11
dc.identifier.citation	Int J Environ Res Public Health, 2022, 19, (8), pp. 4586
dc.identifier.issn	1661-7827
dc.identifier.issn	1660-4601
dc.identifier.uri	http://hdl.handle.net/10453/159644
dc.description.abstract	Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron variants were estimated to lead to more severity and deaths than other variants. Furthermore, these variants have some contagious characteristics involving high transmissibility, more severe illness, and an increased mortality rate. All outbreaks caused by the Delta variant have been rapidly skyrocketing in infection cases in communities despite tough restrictions in 2021. Apart from it, the United States, the United Kingdom and other high-rate vaccination rollout countries are still wrestling with this trend because the Delta variant can result in a significant number of breakthrough infections. However, the pandemic has changed since the latest SARS-CoV-2 variant in late 2021 in South Africa, Omicron. The preliminary data suggest that the Omicron variant possesses 100-fold greater than the Delta variant in transmissibility. Therefore, this paper aims to review these characteristics based on the available meta-data and information from the first emergence to recent days. Australia and the five most affected countries, including the United States, India, Brazil, France, as well as the United Kingdom, are selected in order to review the transmissibility, severity and fatality due to Delta and Omicron variants. Finally, the vaccination programs for each country are also reviewed as the main factor in prevention.
dc.format	Electronic
dc.language	eng
dc.publisher	MDPI
dc.relation.ispartof	Int J Environ Res Public Health
dc.relation.isbasedon	10.3390/ijerph19084586
dc.rights	Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
dc.rights	info:eu-repo/semantics/openAccess
dc.subject.classification	Toxicology
dc.subject.mesh	COVID-19
dc.subject.mesh	Disease Outbreaks
dc.subject.mesh	Humans
dc.subject.mesh	Pandemics
dc.subject.mesh	SARS-CoV-2
dc.subject.mesh	United States
dc.subject.mesh	Humans
dc.subject.mesh	Disease Outbreaks
dc.subject.mesh	United States
dc.subject.mesh	Pandemics
dc.subject.mesh	COVID-19
dc.subject.mesh	SARS-CoV-2
dc.title	Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
dc.type	Journal Article
utslib.citation.volume	19
utslib.location.activity	Switzerland
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Mechanical and Mechatronic Engineering
utslib.copyright.status	open_access	*
dc.date.updated	2022-08-05T04:05:26Z
pubs.issue	8
pubs.publication-status	Published online
pubs.volume	19
utslib.citation.issue	8

Abstract:

Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron variants were estimated to lead to more severity and deaths than other variants. Furthermore, these variants have some contagious characteristics involving high transmissibility, more severe illness, and an increased mortality rate. All outbreaks caused by the Delta variant have been rapidly skyrocketing in infection cases in communities despite tough restrictions in 2021. Apart from it, the United States, the United Kingdom and other high-rate vaccination rollout countries are still wrestling with this trend because the Delta variant can result in a significant number of breakthrough infections. However, the pandemic has changed since the latest SARS-CoV-2 variant in late 2021 in South Africa, Omicron. The preliminary data suggest that the Omicron variant possesses 100-fold greater than the Delta variant in transmissibility. Therefore, this paper aims to review these characteristics based on the available meta-data and information from the first emergence to recent days. Australia and the five most affected countries, including the United States, India, Brazil, France, as well as the United Kingdom, are selected in order to review the transmissibility, severity and fatality due to Delta and Omicron variants. Finally, the vaccination programs for each country are also reviewed as the main factor in prevention.

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http://hdl.handle.net/10453/159644