Region-media coupling in characterization and modelling of the disc annulus single lamella swelling.

Tavakoli, J

Region-media coupling in characterization and modelling of the disc annulus single lamella swelling.

Tavakoli, J

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Publisher:: Springer
Publication Type:: Journal Article
Citation:: Medical and Biological Engineering and Computing, 2017, 55, (8), pp. 1483-1492
Issue Date:: 2017-08

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Field	Value	Language
dc.contributor.author	Tavakoli, J https://orcid.org/0000-0002-0696-6530
dc.date.accessioned	2022-08-30T02:19:29Z
dc.date.available	2016-12-24
dc.date.available	2022-08-30T02:19:29Z
dc.date.issued	2017-08
dc.identifier.citation	Medical and Biological Engineering and Computing, 2017, 55, (8), pp. 1483-1492
dc.identifier.issn	0140-0118
dc.identifier.issn	1741-0444
dc.identifier.uri	http://hdl.handle.net/10453/161093
dc.description.abstract	The annulus fibrosus (AF) swelling property, which is correlated with its rheological and viscoelastic properties, plays a significant role in disc nutrition and mechanical loading justification during daily activities as well as designing scaffolds for tissue engineering applications. The objective of this study was twofold: firstly to characterize the AF single lamella swelling kinetics in different regions and solutions at the temperature range of 35-40 °C and secondly to use the swelling results as a baseline to model (independent to swelling media and anatomic region) the AF single lamella swelling. It was found that the AF single lamella swelling kinetics (equilibrium swelling ratio and swelling rate) depends on anatomic region and swelling media; however, its trend for different swelling media (ionic and molecular solution) is similar and the majority of hydration occurs during first 20% of equilibrium swelling time (about 20 min). Change in swelling rate constant in circumferential direction depends on the solution type. It decreases from anterior to lateral regions for water, PBS and glucose solution and remains constant-or its change is negligible-from lateral to posterolateral regions. The effect of temperature (in the range of 35-40 °C) on swelling kinetics was seen to be negligible. It was also understood that it is possible to present a model (independent to swelling media type) to predict the swelling kinetics of posterior and posterolateral AF single lamella, as these locations are less sensitive to the swelling media.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Springer
dc.relation.ispartof	Medical and Biological Engineering and Computing
dc.relation.isbasedon	10.1007/s11517-016-1609-3
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0903 Biomedical Engineering, 0906 Electrical and Electronic Engineering
dc.subject.classification	Biomedical Engineering
dc.subject.mesh	Animals
dc.subject.mesh	Annulus Fibrosus
dc.subject.mesh	Body Water
dc.subject.mesh	Computer Simulation
dc.subject.mesh	Elastic Modulus
dc.subject.mesh	Hardness
dc.subject.mesh	In Vitro Techniques
dc.subject.mesh	Models, Biological
dc.subject.mesh	Organ Size
dc.subject.mesh	Osmotic Pressure
dc.subject.mesh	Sheep
dc.subject.mesh	Stress, Mechanical
dc.subject.mesh	Viscosity
dc.subject.mesh	Animals
dc.subject.mesh	Annulus Fibrosus
dc.subject.mesh	Body Water
dc.subject.mesh	Computer Simulation
dc.subject.mesh	Elastic Modulus
dc.subject.mesh	Hardness
dc.subject.mesh	In Vitro Techniques
dc.subject.mesh	Models, Biological
dc.subject.mesh	Organ Size
dc.subject.mesh	Osmotic Pressure
dc.subject.mesh	Sheep
dc.subject.mesh	Stress, Mechanical
dc.subject.mesh	Viscosity
dc.subject.mesh	Body Water
dc.subject.mesh	Animals
dc.subject.mesh	Sheep
dc.subject.mesh	Organ Size
dc.subject.mesh	Osmotic Pressure
dc.subject.mesh	Viscosity
dc.subject.mesh	Stress, Mechanical
dc.subject.mesh	Hardness
dc.subject.mesh	Models, Biological
dc.subject.mesh	Computer Simulation
dc.subject.mesh	Elastic Modulus
dc.subject.mesh	In Vitro Techniques
dc.subject.mesh	Annulus Fibrosus
dc.title	Region-media coupling in characterization and modelling of the disc annulus single lamella swelling.
dc.type	Journal Article
utslib.citation.volume	55
utslib.location.activity	United States
utslib.for	0903 Biomedical Engineering
utslib.for	0906 Electrical and Electronic Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Centre for Health Technologies (CHT)
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2022-08-30T02:19:27Z
pubs.issue	8
pubs.publication-status	Published
pubs.volume	55
utslib.citation.issue	8

Abstract:

The annulus fibrosus (AF) swelling property, which is correlated with its rheological and viscoelastic properties, plays a significant role in disc nutrition and mechanical loading justification during daily activities as well as designing scaffolds for tissue engineering applications. The objective of this study was twofold: firstly to characterize the AF single lamella swelling kinetics in different regions and solutions at the temperature range of 35-40 °C and secondly to use the swelling results as a baseline to model (independent to swelling media and anatomic region) the AF single lamella swelling. It was found that the AF single lamella swelling kinetics (equilibrium swelling ratio and swelling rate) depends on anatomic region and swelling media; however, its trend for different swelling media (ionic and molecular solution) is similar and the majority of hydration occurs during first 20% of equilibrium swelling time (about 20 min). Change in swelling rate constant in circumferential direction depends on the solution type. It decreases from anterior to lateral regions for water, PBS and glucose solution and remains constant-or its change is negligible-from lateral to posterolateral regions. The effect of temperature (in the range of 35-40 °C) on swelling kinetics was seen to be negligible. It was also understood that it is possible to present a model (independent to swelling media type) to predict the swelling kinetics of posterior and posterolateral AF single lamella, as these locations are less sensitive to the swelling media.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/161093