Nanoparticle-mediated singlet oxygen generation from photosensitizers

Clement, S; Sobhan, M; Deng, W; Camilleri, E; Goldys, EM

Nanoparticle-mediated singlet oxygen generation from photosensitizers

Clement, S Sobhan, M Deng, W

Camilleri, E Goldys, EM

Permalink

Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: Journal of Photochemistry and Photobiology A: Chemistry, 2017, 332, pp. 66-71
Issue Date:: 2017-01-01

Closed Access

	Filename	Description	Size
	1-s2.0-S1010603016304476-main.pdf		1.04 MB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Clement, S
dc.contributor.author	Sobhan, M
dc.contributor.author	Deng, W https://orcid.org/0000-0002-9413-0978
dc.contributor.author	Camilleri, E
dc.contributor.author	Goldys, EM
dc.date.accessioned	2022-09-06T00:27:01Z
dc.date.available	2022-09-06T00:27:01Z
dc.date.issued	2017-01-01
dc.identifier.citation	Journal of Photochemistry and Photobiology A: Chemistry, 2017, 332, pp. 66-71
dc.identifier.issn	1010-6030
dc.identifier.issn	1873-2666
dc.identifier.uri	http://hdl.handle.net/10453/161397
dc.description.abstract	We report on the modification of the efficiency of singlet oxygen generation in photosensitizers conjugated to dielectric (CeF3) and metal (Au) nanoparticles in water. The conjugates were formed with two photosensitizers, verteporfin and Rose Bengal. Quantitative analysis of the singlet oxygen generation demonstrated that the conjugation of the photosensitizer to a nanoparticle increases the efficiency of the photosensitizers to produce singlet oxygen in water. The singlet oxygen quantum yield of UV-sensitized verteporfin increases by a factor of 1.45 and 1.64 for CeF3-verteporfin and Au-verteporfin conjugates respectively compared to unconjugated verteporfin. Furthermore, Au-Rose Bengal conjugates also demonstrated enhanced singlet oxygen yield when sensitized at the plasmonic wavelength of 532 nm. We quantitatively explain these findings by the electric field enhancements around the nanoparticles.
dc.language	English
dc.publisher	Elsevier
dc.relation	http://purl.org/au-research/grants/arc/CE140100003
dc.relation.ispartof	Journal of Photochemistry and Photobiology A: Chemistry
dc.relation.isbasedon	10.1016/j.jphotochem.2016.08.009
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	03 Chemical Sciences, 06 Biological Sciences, 09 Engineering
dc.subject.classification	Chemical Physics
dc.title	Nanoparticle-mediated singlet oxygen generation from photosensitizers
dc.type	Journal Article
utslib.citation.volume	332
utslib.for	03 Chemical Sciences
utslib.for	06 Biological Sciences
utslib.for	09 Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2022-09-06T00:26:59Z
pubs.publication-status	Published
pubs.volume	332

Abstract:

We report on the modification of the efficiency of singlet oxygen generation in photosensitizers conjugated to dielectric (CeF3) and metal (Au) nanoparticles in water. The conjugates were formed with two photosensitizers, verteporfin and Rose Bengal. Quantitative analysis of the singlet oxygen generation demonstrated that the conjugation of the photosensitizer to a nanoparticle increases the efficiency of the photosensitizers to produce singlet oxygen in water. The singlet oxygen quantum yield of UV-sensitized verteporfin increases by a factor of 1.45 and 1.64 for CeF3-verteporfin and Au-verteporfin conjugates respectively compared to unconjugated verteporfin. Furthermore, Au-Rose Bengal conjugates also demonstrated enhanced singlet oxygen yield when sensitized at the plasmonic wavelength of 532 nm. We quantitatively explain these findings by the electric field enhancements around the nanoparticles.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/161397