Comparing multi-attribute utility instruments: CP-6D, a Cerebral palsy specific instrument, vs AQoL-4D.

Bahrampour, M; Downes, M; Scuffham, PA; Byrnes, J

Comparing multi-attribute utility instruments: CP-6D, a Cerebral palsy specific instrument, vs AQoL-4D.

Bahrampour, M

Downes, M Scuffham, PA Byrnes, J

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Publisher:: Taylor and Francis Group
Publication Type:: Journal Article
Citation:: Expert Review of Pharmacoeconomics and Outcomes Research: informing decision-making in the delivery of cost-effective healthcare, 2022, 22, (2), pp. 217-224
Issue Date:: 2022-04-08

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Field	Value	Language
dc.contributor.author	Bahrampour, M https://orcid.org/0000-0002-6915-1865
dc.contributor.author	Downes, M
dc.contributor.author	Scuffham, PA
dc.contributor.author	Byrnes, J
dc.date.accessioned	2022-10-27T03:56:51Z
dc.date.available	2022-10-27T03:56:51Z
dc.date.issued	2022-04-08
dc.identifier.citation	Expert Review of Pharmacoeconomics and Outcomes Research: informing decision-making in the delivery of cost-effective healthcare, 2022, 22, (2), pp. 217-224
dc.identifier.issn	1473-7167
dc.identifier.issn	1744-8379
dc.identifier.uri	http://hdl.handle.net/10453/162749
dc.description.abstract	Background: Economic-evaluations of Cerebral palsy (CP) were based on utility estimates of health-related quality of life (HRQoL) from generic multi-attribute utility instruments (MAUIs). However, generic instruments had limited use as they could not capture some of the important aspects of living with CP. The Cerebral palsy 6 Dimension (CP-6D) is a disease specific MAUI. In this study, we compared the results of CP-6D with the Assessment of Quality of Life (AQoL-4D), a generic MAUI, and tested the criterion validity of the CP-6D in the general population.Methods:An online survey of the Australian general population (n = 2002), who completed both the AQoL-4D and CP-6D MAUIs, was conducted. Validity was assessed from the correlations between the domains, items and instruments. ANOVA and t-tests were used to assess the instrument's discrimination in different social demographic categories.Results:There was a moderate correlation between the instruments (0.64). Differences in socio-demographic characteristics showed a medium effect size (p < 0.001) in both instruments and had a similar effect on utility weights in both instruments. Although the CP-6D was more sensitive to changes in income and education.Conclusions: Our results suggest that CP-6D and AQoL-4D were measuring a similar underlying construct. Both instruments responded similarly to socio-demographic differences.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Taylor and Francis Group
dc.relation.ispartof	Expert Review of Pharmacoeconomics and Outcomes Research: informing decision-making in the delivery of cost-effective healthcare
dc.relation.isbasedon	10.1080/14737167.2021.1909477
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences, 1117 Public Health and Health Services, 1402 Applied Economics
dc.subject.classification	Health Policy & Services
dc.subject.mesh	Australia
dc.subject.mesh	Cerebral Palsy
dc.subject.mesh	Cost-Benefit Analysis
dc.subject.mesh	Humans
dc.subject.mesh	Quality of Life
dc.subject.mesh	Surveys and Questionnaires
dc.subject.mesh	Humans
dc.subject.mesh	Cerebral Palsy
dc.subject.mesh	Quality of Life
dc.subject.mesh	Cost-Benefit Analysis
dc.subject.mesh	Australia
dc.subject.mesh	Surveys and Questionnaires
dc.title	Comparing multi-attribute utility instruments: CP-6D, a Cerebral palsy specific instrument, vs AQoL-4D.
dc.type	Journal Article
utslib.citation.volume	22
utslib.location.activity	England
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
utslib.for	1117 Public Health and Health Services
utslib.for	1402 Applied Economics
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Centre for Health Economics Research and Evaluation
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2022-10-27T03:56:50Z
pubs.issue	2
pubs.publication-status	Published
pubs.volume	22
utslib.citation.issue	2

Abstract:

Background: Economic-evaluations of Cerebral palsy (CP) were based on utility estimates of health-related quality of life (HRQoL) from generic multi-attribute utility instruments (MAUIs). However, generic instruments had limited use as they could not capture some of the important aspects of living with CP. The Cerebral palsy 6 Dimension (CP-6D) is a disease specific MAUI. In this study, we compared the results of CP-6D with the Assessment of Quality of Life (AQoL-4D), a generic MAUI, and tested the criterion validity of the CP-6D in the general population.Methods:An online survey of the Australian general population (n = 2002), who completed both the AQoL-4D and CP-6D MAUIs, was conducted. Validity was assessed from the correlations between the domains, items and instruments. ANOVA and t-tests were used to assess the instrument's discrimination in different social demographic categories.Results:There was a moderate correlation between the instruments (0.64). Differences in socio-demographic characteristics showed a medium effect size (p < 0.001) in both instruments and had a similar effect on utility weights in both instruments. Although the CP-6D was more sensitive to changes in income and education.Conclusions: Our results suggest that CP-6D and AQoL-4D were measuring a similar underlying construct. Both instruments responded similarly to socio-demographic differences.

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http://hdl.handle.net/10453/162749