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Expanding health technology assessment towards broader value: Ireland as a case study.

Kinchin, I Walshe, V Normand, C Coast, J Elliott, R Kroll, T Kinghorn, P Thompson, A Viney, R Currow, D O'Mahony, JF

Healthcare innovations often represent important improvements in population welfare, but at what cost, and to whom? Health technology assessment (HTA) is a multidisciplinary process to inform resou...

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Understanding Training Load as Exposure and Dose.

Impellizzeri, FM Shrier, I McLaren, SJ Coutts, AJ McCall, A Slattery, K Jeffries, AC Kalkhoven, JT

Various terms used in sport and exercise science, and medicine, are derived from other fields such as epidemiology, pharmacology and causal inference. Conceptual and nomological frameworks have des...

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Effect of core versus enhanced implementation strategies on adherence to a clinical pathway for managing anxiety and depression in cancer patients in routine care: a cluster randomised controlled trial.

Butow, P Faris, MM Shaw, J Kelly, P He, S Harris, M Cuddy, J Masya, L Geerligs, L Kelly, B Girgis, A Rankin, N Beale, P Hack, TF Kirsten, L Dhillon, H Grimison, P Viney, R Clayton, JM Schlub, T ADAPT Program Group, Shepherd, HL

BACKGROUND: Optimal strategies to facilitate implementation of evidence-based clinical pathways are unclear. We evaluated two implementation strategies (Core versus Enhanced) to facilitate implemen...

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Understanding the valuation of paediatric health-related quality of life: a qualitative study protocol.

Yu, A Luo, Y Bahrampour, M Norman, R Street, D Viney, R Devlin, N Mulhern, BJ Quality Of Life in Kids: Key evidence to strengthen decisions in Australia (QUOKKA) project team,

INTRODUCTION: There is evidence from previous studies that adults value paediatric health-related quality of life (HRQoL) and adult HRQoL differently. Less is known about how adolescents value paed...

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Multinational Analysis of Estimated Health Care Costs Related to Extended-Interval Fixed Dosing of Checkpoint Inhibitors.

Goldstein, DA Ginsberg, GM Hofnung-Gabbay, D De Abreu Lourenco, R Loong, HH Goh, BC Chan, KKW Di Maio, M Perrone, F Hall, PS Zer, A Rosenbaum, E

IMPORTANCE: New dosing options for immune checkpoint inhibitors have recently been approved by the US Food and Drug Administration (FDA), including fixed dosing with extended intervals. Although th...

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Men's perceptions and preferences regarding prostate cancer radiation therapy: A systematic scoping review.

Brown, A Yim, J Jones, S Tan, A Callander, E Watt, K De Abreu Lourenco, R Pain, T

PURPOSE: To assess the literature on men's preferences and perceptions regarding prostate cancer radiation therapy. METHODS: A scoping review was undertaken as per JBI guidelines. Searches were con...

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Education messages and strategies to inform the public, potential screening candidates and healthcare providers about lung cancer screening: A systematic review.

Dodd, RH Sharman, AR McGregor, D Stone, E Donnelly, C Lourenco, RDA Marshall, H Rankin, NM

International lung cancer screening (LCS) trials, using low-dose computed tomography, have demonstrated clinical effectiveness in reducing mortality from lung cancer. This systematic review aims to...

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Reduced Peak Bone Mass in Young Adults With Low Motor Competence.

Tan, J Ng, C-A Hart, NH Rantalainen, T Sim, M Scott, D Zhu, K Hands, B Chivers, P

Although suboptimal bone health has been reported in children and adolescents with low motor competence (LMC), it is not known whether such deficits are present at the time of peak bone mass. We ex...

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Autonomous assessment of spontaneous retinal venous pulsations in fundus videos using a deep learning framework

Panahi, A Rezaee, A Hajati, F Shariflou, S Agar, A Golzan, SM

AbstractThe presence or absence of spontaneous retinal venous pulsations (SVP) provides clinically significant insight into the hemodynamic status of the optic nerv...

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Treatment patterns and out-of-hospital healthcare resource utilisation by patients with advanced cancer living with pain: An analysis from the Stop Cancer PAIN trial.

McCaffrey, N Cheah, SL Luckett, T Phillips, JL Agar, M Davidson, PM Boyle, F Shaw, T Currow, DC Lovell, M

BACKGROUND: About 70% of patients with advanced cancer experience pain. Few studies have investigated the use of healthcare in this population and the relationship between pain intensity and costs....

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