A targeted metabolic analysis of football players and its association to player load: Comparison between women and men profiles.

Rodas, G; Ferrer, E; Reche, X; Sanjuan-Herráez, JD; McCall, A; Quintás, G

A targeted metabolic analysis of football players and its association to player load: Comparison between women and men profiles.

Rodas, G Ferrer, E Reche, X Sanjuan-Herráez, JD McCall, A

Quintás, G

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Publisher:: Frontiers Media
Publication Type:: Journal Article
Citation:: Frontiers in Physiology, 2022, 13, pp. 1-10
Issue Date:: 2022

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Field	Value	Language
dc.contributor.author	Rodas, G
dc.contributor.author	Ferrer, E
dc.contributor.author	Reche, X
dc.contributor.author	Sanjuan-Herráez, JD
dc.contributor.author	McCall, A https://orcid.org/0000-0003-3780-8153
dc.contributor.author	Quintás, G
dc.date.accessioned	2022-10-28T01:27:14Z
dc.date.available	2022-09-14
dc.date.available	2022-10-28T01:27:14Z
dc.date.issued	2022
dc.identifier.citation	Frontiers in Physiology, 2022, 13, pp. 1-10
dc.identifier.issn	1664-042X
dc.identifier.issn	1664-042X
dc.identifier.uri	http://hdl.handle.net/10453/162777
dc.description.abstract	Professional athletes undertake a variety of training programs to enhance their physical performance, technical-tactical skills, while protecting their health and well-being. Regular exercise induces widespread changes in the whole body in an extremely complex network of signaling, and evidence indicates that phenotypical sex differences influence the physiological adaptations to player load of professional athletes. Despite that there remains an underrepresentation of women in clinical studies in sports, including football. The objectives of this study were twofold: to study the association between the external load (EPTS) and urinary metabolites as a surrogate of the adaptation to training, and to assess the effect of sex on the physiological adaptations to player load in professional football players. Targeted metabolic analysis of aminoacids, and tryptophan and phenylalanine metabolites detected progressive changes in the urinary metabolome associated with the external training load in men and women's football teams. Overrepresentation analysis and multivariate analysis of metabolic data showed significant differences of the effect of training on the metabolic profiles in the men and women teams analyzed. Collectively, our results demonstrate that the development of metabolic models of adaptation in professional football players can benefit from the separate analysis of women and men teams, providing more accurate insights into how adaptation to the external load is related to changes in the metabolic phenotypes. Furthermore, results support the use of metabolomics to understand changes in specific metabolic pathways provoked by the training process.
dc.language	eng
dc.publisher	Frontiers Media
dc.relation.ispartof	Frontiers in Physiology
dc.relation.isbasedon	10.3389/fphys.2022.923608
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	0606 Physiology, 1116 Medical Physiology, 1701 Psychology
dc.title	A targeted metabolic analysis of football players and its association to player load: Comparison between women and men profiles.
dc.type	Journal Article
utslib.citation.volume	13
utslib.location.activity	Switzerland
utslib.for	0606 Physiology
utslib.for	1116 Medical Physiology
utslib.for	1701 Psychology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
pubs.consider-herdc	false
dc.date.updated	2022-10-28T01:27:11Z
pubs.publication-status	Published
pubs.volume	13

Abstract:

Professional athletes undertake a variety of training programs to enhance their physical performance, technical-tactical skills, while protecting their health and well-being. Regular exercise induces widespread changes in the whole body in an extremely complex network of signaling, and evidence indicates that phenotypical sex differences influence the physiological adaptations to player load of professional athletes. Despite that there remains an underrepresentation of women in clinical studies in sports, including football. The objectives of this study were twofold: to study the association between the external load (EPTS) and urinary metabolites as a surrogate of the adaptation to training, and to assess the effect of sex on the physiological adaptations to player load in professional football players. Targeted metabolic analysis of aminoacids, and tryptophan and phenylalanine metabolites detected progressive changes in the urinary metabolome associated with the external training load in men and women's football teams. Overrepresentation analysis and multivariate analysis of metabolic data showed significant differences of the effect of training on the metabolic profiles in the men and women teams analyzed. Collectively, our results demonstrate that the development of metabolic models of adaptation in professional football players can benefit from the separate analysis of women and men teams, providing more accurate insights into how adaptation to the external load is related to changes in the metabolic phenotypes. Furthermore, results support the use of metabolomics to understand changes in specific metabolic pathways provoked by the training process.

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http://hdl.handle.net/10453/162777