Standardising definitions for the pre-eclampsia core outcome set: A consensus development study.

Duffy, JMN; Cairns, AE; Magee, LA; von Dadelszen, P; van 't Hooft, J; Gale, C; Brown, M; Chappell, LC; Grobman, WA; Fitzpatrick, R; Karumanchi, SA; Lucas, DN; Mol, B; Stark, M; Thangaratinam, S; Wilson, MJ; Williamson, PR; Ziebland, S; McManus, RJ; International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE),

Standardising definitions for the pre-eclampsia core outcome set: A consensus development study.

Duffy, JMN Cairns, AE Magee, LA von Dadelszen, P van 't Hooft, J Gale, C Brown, M Chappell, LC Grobman, WA Fitzpatrick, R Karumanchi, SA Lucas, DN Mol, B Stark, M Thangaratinam, S Wilson, MJ Williamson, PR Ziebland, S McManus, RJ International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE),

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Publisher:: Elsevier BV
Publication Type:: Journal Article
Citation:: Pregnancy Hypertens, 2020, 21, pp. 208-217
Issue Date:: 2020-07

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Field	Value	Language
dc.contributor.author	Duffy, JMN
dc.contributor.author	Cairns, AE
dc.contributor.author	Magee, LA
dc.contributor.author	von Dadelszen, P
dc.contributor.author	van 't Hooft, J
dc.contributor.author	Gale, C
dc.contributor.author	Brown, M
dc.contributor.author	Chappell, LC
dc.contributor.author	Grobman, WA
dc.contributor.author	Fitzpatrick, R
dc.contributor.author	Karumanchi, SA
dc.contributor.author	Lucas, DN
dc.contributor.author	Mol, B
dc.contributor.author	Stark, M
dc.contributor.author	Thangaratinam, S
dc.contributor.author	Wilson, MJ
dc.contributor.author	Williamson, PR
dc.contributor.author	Ziebland, S
dc.contributor.author	McManus, RJ
dc.contributor.author	International Collaboration to Harmonise Outcomes for Pre-eclampsia (iHOPE),
dc.date.accessioned	2022-10-30T19:04:23Z
dc.date.available	2020-06-14
dc.date.available	2022-10-30T19:04:23Z
dc.date.issued	2020-07
dc.identifier.citation	Pregnancy Hypertens, 2020, 21, pp. 208-217
dc.identifier.issn	2210-7789
dc.identifier.issn	2210-7797
dc.identifier.uri	http://hdl.handle.net/10453/162943
dc.description.abstract	OBJECTIVES: To develop consensus definitions for the core outcome set for pre-eclampsia. STUDY DESIGN: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. RESULTS: Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. CONCLUSIONS: Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier BV
dc.relation.ispartof	Pregnancy Hypertens
dc.relation.isbasedon	10.1016/j.preghy.2020.06.005
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1114 Paediatrics and Reproductive Medicine
dc.subject.mesh	Adult
dc.subject.mesh	Consensus
dc.subject.mesh	Delphi Technique
dc.subject.mesh	Female
dc.subject.mesh	Humans
dc.subject.mesh	Pre-Eclampsia
dc.subject.mesh	Pregnancy
dc.subject.mesh	Pregnancy Complications
dc.subject.mesh	Pregnancy Outcome
dc.subject.mesh	Reference Standards
dc.subject.mesh	Treatment Outcome
dc.subject.mesh	Humans
dc.subject.mesh	Pregnancy Complications
dc.subject.mesh	Pre-Eclampsia
dc.subject.mesh	Pregnancy Outcome
dc.subject.mesh	Treatment Outcome
dc.subject.mesh	Consensus
dc.subject.mesh	Pregnancy
dc.subject.mesh	Reference Standards
dc.subject.mesh	Delphi Technique
dc.subject.mesh	Adult
dc.subject.mesh	Female
dc.title	Standardising definitions for the pre-eclampsia core outcome set: A consensus development study.
dc.type	Journal Article
utslib.citation.volume	21
utslib.location.activity	Netherlands
utslib.for	1114 Paediatrics and Reproductive Medicine
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	/University of Technology Sydney/Strength - WHO CC
utslib.copyright.status	closed_access	*
dc.date.updated	2022-10-30T19:04:21Z
pubs.publication-status	Published
pubs.volume	21

Abstract:

OBJECTIVES: To develop consensus definitions for the core outcome set for pre-eclampsia. STUDY DESIGN: Potential definitions for individual core outcomes were identified across four formal definition development initiatives, nine national and international guidelines, 12 Cochrane systematic reviews, and 79 randomised trials. Eighty-six definitions were entered into the consensus development meeting. Ten healthcare professionals and three researchers, including six participants who had experience of conducting research in low- and middle-income countries, participated in the consensus development process. The final core outcome set was approved by an international steering group. RESULTS: Consensus definitions were developed for all core outcomes. When considering stroke, pulmonary oedema, acute kidney injury, raised liver enzymes, low platelets, birth weight, and neonatal seizures, consensus definitions were developed specifically for low- and middle-income countries because of the limited availability of diagnostic interventions including computerised tomography, chest x-ray, laboratory tests, equipment, and electroencephalogram monitoring. CONCLUSIONS: Consensus on measurements for the pre-eclampsia core outcome set will help to ensure consistency across future randomised trials and systematic reviews. Such standardization should make research evidence more accessible and facilitate the translation of research into clinical practice. Video abstract can be available at: www.dropbox.com/s/ftrgvrfu0u9glqd/6.%20Standardising%20definitions%20in%20teh%20pre-eclampsia%20core%20outcome%20set%3A%20a%20consensus%20development%20study.mp4?dl=0.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/162943