Rapid diagnosis of infectious diseases using microfluidic systems
- Publisher:
- CRC Press
- Publication Type:
- Chapter
- Citation:
- Diagnostic Devices with Microfluidics, 2017, pp. 145-161
- Issue Date:
- 2017-01-01
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| Filename | Description | Size | |||
|---|---|---|---|---|---|
| Diagnostic_Devices_with_Microfluidics_----_(Chapter_7_Rapid_Diagnosis_of_Infectious_Diseases_Using_Microfluidic_Sy...).pdf | Published version | 2.12 MB |
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Infectious diseases remain the primary public health challenge in many countries. Every year, infectious diseases account for more than 13 million deaths around the world, and for 30% of the total burden of disease. Developing countries are especially challenged with infectious diseases. According to world health organization (WHO), 50% of the total deaths in developing countries are attributed to various infections, including respiratory tract infections, diarrheal diseases, human immunodeficiency virus (HIV), tuberculosis, and malaria. In the healthcare system, a diagnostic cycle consists of several time-consuming steps besides sample transportation, pre-and postanalytical phases, result transmission, and batching practices augmenting the turnaround time from disease interpretation to results (Figure 7.1) [1-3]. The downside of experience-based empiric therapy management involves the choice of inappropriate antibiotherapy or late initiation of treatment often resulting in treatment failure [4-7].
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