Cardiac postacute sequelae symptoms of SARS-CoV-2 in community-dwelling adults: cross-sectional study

Ogungbe, O; Gilotra, NA; Davidson, PM; Farley, JE; Dennison Himmelfarb, CR; Post, WS; Commodore-Mensah, Y

Cardiac postacute sequelae symptoms of SARS-CoV-2 in community-dwelling adults: cross-sectional study

Ogungbe, O Gilotra, NA Davidson, PM Farley, JE Dennison Himmelfarb, CR Post, WS Commodore-Mensah, Y

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Publisher:: BMJ
Publication Type:: Journal Article
Citation:: Open heart, 2022, 9, (2), pp. e002084
Issue Date:: 2022-01

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Field	Value	Language
dc.contributor.author	Ogungbe, O
dc.contributor.author	Gilotra, NA
dc.contributor.author	Davidson, PM
dc.contributor.author	Farley, JE
dc.contributor.author	Dennison Himmelfarb, CR
dc.contributor.author	Post, WS
dc.contributor.author	Commodore-Mensah, Y
dc.date.accessioned	2023-01-19T03:02:37Z
dc.date.available	2023-01-19T03:02:37Z
dc.date.issued	2022-01
dc.identifier.citation	Open heart, 2022, 9, (2), pp. e002084
dc.identifier.issn	2053-3624
dc.identifier.issn	2053-3624
dc.identifier.uri	http://hdl.handle.net/10453/165189
dc.description.abstract	<h4>Objective</h4> To examine risk factors for cardiac-related postacute sequelae of SARS-CoV-2 infection (PASC) in community-dwelling adults after acute COVID-19 infection. <h4>Methods</h4> We performed a cross-sectional analysis among adults who tested positive for COVID-19. Outcomes were self-reported cardiac-related PASC. We conducted stepwise multivariable logistic regression to assess association between the risk factors (existing cardiovascular disease (CVD), pre-existing conditions, days since positive test, COVID-19 hospitalisation, age, sex, education, income) and cardiac-related PASC. <h4>Results</h4> In a sample of 442 persons, mean (SD) age was 45.4 (16.2) years, 71% were women, 13% were black, 46% had pre-existing conditions, 23% had cardiovascular (CV) risk factors and 4% had CVD. Prevalence of cardiac PASC was 43% and newly diagnosed cardiac conditions were 27%. The odds for cardiac-related PASC were higher among persons with underlying pre-existing conditions (adjusted OR (aOR): 2.00, 95% CI: 1.28 to 3.10) and among those who were hospitalised (aOR: 3.03, 95% CI: 1.58 to 5.83). <h4>Conclusions</h4> More than a third of persons with COVID-19 reported cardiac-related PASC symptoms. Underlying CVD, pre-existing diseases, age and COVID-19 hospitalisation are possible risk factors for cardiac-related PASC symptoms. COVID-19 may exacerbate CV risk factors and increase risk of complications.
dc.format	Undetermined
dc.language	eng
dc.publisher	BMJ
dc.relation.ispartof	Open heart
dc.relation.isbasedon	10.1136/openhrt-2022-002084
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Cardiac postacute sequelae symptoms of SARS-CoV-2 in community-dwelling adults: cross-sectional study
dc.type	Journal Article
utslib.citation.volume	9
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
dc.date.updated	2023-01-19T03:02:36Z
pubs.issue	2
pubs.publication-status	Published
pubs.volume	9
utslib.citation.issue	2

Abstract:

Objective

To examine risk factors for cardiac-related postacute sequelae of SARS-CoV-2 infection (PASC) in community-dwelling adults after acute COVID-19 infection.

Methods

We performed a cross-sectional analysis among adults who tested positive for COVID-19. Outcomes were self-reported cardiac-related PASC. We conducted stepwise multivariable logistic regression to assess association between the risk factors (existing cardiovascular disease (CVD), pre-existing conditions, days since positive test, COVID-19 hospitalisation, age, sex, education, income) and cardiac-related PASC.

Results

In a sample of 442 persons, mean (SD) age was 45.4 (16.2) years, 71% were women, 13% were black, 46% had pre-existing conditions, 23% had cardiovascular (CV) risk factors and 4% had CVD. Prevalence of cardiac PASC was 43% and newly diagnosed cardiac conditions were 27%. The odds for cardiac-related PASC were higher among persons with underlying pre-existing conditions (adjusted OR (aOR): 2.00, 95% CI: 1.28 to 3.10) and among those who were hospitalised (aOR: 3.03, 95% CI: 1.58 to 5.83).

Conclusions

More than a third of persons with COVID-19 reported cardiac-related PASC symptoms. Underlying CVD, pre-existing diseases, age and COVID-19 hospitalisation are possible risk factors for cardiac-related PASC symptoms. COVID-19 may exacerbate CV risk factors and increase risk of complications.

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http://hdl.handle.net/10453/165189