Characterisation of children hospitalised with pneumonia in central Vietnam: a prospective study.

Nguyen, PTK; Tran, HT; Fitzgerald, DA; Tran, TS; Graham, SM; Marais, BJ

Characterisation of children hospitalised with pneumonia in central Vietnam: a prospective study.

Nguyen, PTK Tran, HT Fitzgerald, DA Tran, TS Graham, SM Marais, BJ

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Publisher:: EUROPEAN RESPIRATORY SOC JOURNALS LTD
Publication Type:: Journal Article
Citation:: Eur Respir J, 2019, 54, (1), pp. 1802256
Issue Date:: 2019-07

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Field	Value	Language
dc.contributor.author	Nguyen, PTK
dc.contributor.author	Tran, HT
dc.contributor.author	Fitzgerald, DA
dc.contributor.author	Tran, TS
dc.contributor.author	Graham, SM
dc.contributor.author	Marais, BJ
dc.date.accessioned	2023-03-19T09:10:09Z
dc.date.available	2019-03-29
dc.date.available	2023-03-19T09:10:09Z
dc.date.issued	2019-07
dc.identifier.citation	Eur Respir J, 2019, 54, (1), pp. 1802256
dc.identifier.issn	0903-1936
dc.identifier.issn	1399-3003
dc.identifier.uri	http://hdl.handle.net/10453/167552
dc.description.abstract	Pneumonia is the most common reason for paediatric hospital admission in Vietnam. The potential value of using the World Health Organization (WHO) case management approach in Vietnam has not been documented.We performed a prospective descriptive study of all children (2-59 months) admitted with "pneumonia" (as assessed by the admitting clinician) to the Da Nang Hospital for Women and Children to characterise their disease profiles and assess risk factors for an adverse outcome. The disease profile was classified using WHO pneumonia criteria, with tachypnoea or chest indrawing as defining clinical signs. Adverse outcome was defined as death, intensive care unit admission, tertiary care transfer or hospital stay >10 days.Of 4206 admissions, 1758 (41.8%) were classified as "no pneumonia" using WHO criteria and only 252 (6.0%) met revised criteria for "severe pneumonia". The inpatient death rate was low (0.4% of admissions) with most deaths (11 out of 16; 68.8%) occurring in the "severe pneumonia" group. An adverse outcome was recorded in 18.7% of all admissions and 60.7% of the "severe pneumonia" group. Children were hospitalised for a median of 7 days at an average cost of 253 USD per admission. Risk factors for adverse outcome included WHO-classified "severe pneumonia", age <1 year, low birth weight, previous recent admission with an acute respiratory infection and recent tuberculosis exposure. Breastfeeding, day-care attendance and pre-admission antibiotic use were associated with reduced risk.Few hospital admissions met WHO criteria for "severe pneumonia", suggesting potential unnecessary hospitalisation and use of intravenous antibiotics. Better characterisation of the underlying diagnosis requires careful consideration.
dc.format	Electronic-Print
dc.language	eng
dc.publisher	EUROPEAN RESPIRATORY SOC JOURNALS LTD
dc.relation.ispartof	Eur Respir J
dc.relation.isbasedon	10.1183/13993003.02256-2018
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	11 Medical and Health Sciences, 1116 Medical Physiology
dc.subject.classification	Respiratory System
dc.subject.mesh	Anti-Bacterial Agents
dc.subject.mesh	Case Management
dc.subject.mesh	Child, Preschool
dc.subject.mesh	Female
dc.subject.mesh	Hospitalization
dc.subject.mesh	Humans
dc.subject.mesh	Infant
dc.subject.mesh	Logistic Models
dc.subject.mesh	Male
dc.subject.mesh	Multivariate Analysis
dc.subject.mesh	Pneumonia
dc.subject.mesh	Prospective Studies
dc.subject.mesh	Risk Factors
dc.subject.mesh	Severity of Illness Index
dc.subject.mesh	Vietnam
dc.subject.mesh	World Health Organization
dc.subject.mesh	Humans
dc.subject.mesh	Pneumonia
dc.subject.mesh	Anti-Bacterial Agents
dc.subject.mesh	Hospitalization
dc.subject.mesh	Severity of Illness Index
dc.subject.mesh	Multivariate Analysis
dc.subject.mesh	Logistic Models
dc.subject.mesh	Risk Factors
dc.subject.mesh	Prospective Studies
dc.subject.mesh	Child, Preschool
dc.subject.mesh	Infant
dc.subject.mesh	World Health Organization
dc.subject.mesh	Case Management
dc.subject.mesh	Vietnam
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Anti-Bacterial Agents
dc.subject.mesh	Case Management
dc.subject.mesh	Child, Preschool
dc.subject.mesh	Female
dc.subject.mesh	Hospitalization
dc.subject.mesh	Humans
dc.subject.mesh	Infant
dc.subject.mesh	Logistic Models
dc.subject.mesh	Male
dc.subject.mesh	Multivariate Analysis
dc.subject.mesh	Pneumonia
dc.subject.mesh	Prospective Studies
dc.subject.mesh	Risk Factors
dc.subject.mesh	Severity of Illness Index
dc.subject.mesh	Vietnam
dc.subject.mesh	World Health Organization
dc.title	Characterisation of children hospitalised with pneumonia in central Vietnam: a prospective study.
dc.type	Journal Article
utslib.citation.volume	54
utslib.location.activity	England
utslib.for	11 Medical and Health Sciences
utslib.for	1116 Medical Physiology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
utslib.copyright.status	closed_access	*
dc.date.updated	2023-03-19T09:10:07Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	54
utslib.citation.issue	1

Abstract:

Pneumonia is the most common reason for paediatric hospital admission in Vietnam. The potential value of using the World Health Organization (WHO) case management approach in Vietnam has not been documented.We performed a prospective descriptive study of all children (2-59 months) admitted with "pneumonia" (as assessed by the admitting clinician) to the Da Nang Hospital for Women and Children to characterise their disease profiles and assess risk factors for an adverse outcome. The disease profile was classified using WHO pneumonia criteria, with tachypnoea or chest indrawing as defining clinical signs. Adverse outcome was defined as death, intensive care unit admission, tertiary care transfer or hospital stay >10 days.Of 4206 admissions, 1758 (41.8%) were classified as "no pneumonia" using WHO criteria and only 252 (6.0%) met revised criteria for "severe pneumonia". The inpatient death rate was low (0.4% of admissions) with most deaths (11 out of 16; 68.8%) occurring in the "severe pneumonia" group. An adverse outcome was recorded in 18.7% of all admissions and 60.7% of the "severe pneumonia" group. Children were hospitalised for a median of 7 days at an average cost of 253 USD per admission. Risk factors for adverse outcome included WHO-classified "severe pneumonia", age <1 year, low birth weight, previous recent admission with an acute respiratory infection and recent tuberculosis exposure. Breastfeeding, day-care attendance and pre-admission antibiotic use were associated with reduced risk.Few hospital admissions met WHO criteria for "severe pneumonia", suggesting potential unnecessary hospitalisation and use of intravenous antibiotics. Better characterisation of the underlying diagnosis requires careful consideration.

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http://hdl.handle.net/10453/167552