Prevalence of Multiple sclerosis and its clinical and demographic characteristics in Kurdish populations in western Iran (2020)
- Publisher:
- Elsevier
- Publication Type:
- Journal Article
- Citation:
- Mult Scler Relat Disord, 2022, 57, (-), pp. 103441
- Issue Date:
- 2022-01-01
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Background Multiple Sclerosis MS is a costly burdensome nervous system disorder leading several disabilities in young and middle aged people Knowing MS clinical epidemiologic and demographic characteristics may help to estimate and predict the required health services and medication facilities for the affected people This study was aimed to determine the prevalence of MS and its demographic characteristic in about 2 million Kurdish populations in western Iran in 2020 Methods This cross sectional study was conducted in 2020 on MS patients with Kurdish Ethnicity living in Kermanshah western Iran which is a Mountainous area in MS patients were registered and recruited to this study from several centers The settings have been approved by the nationwide MS registry of Iran NMSRI Using two questioners a questionnaire included sex age the age in which the MS symptoms onset the age of diagnosis family history of MS and type of MS and second one was the Expanded Disability Status Scale EDSS checklist The demographic information of Kermanshah province was adopted from the Statistical Center of Iran In addition to descriptive statistics U Mann Whitney and Chi square tests were also used Results A total of 1557 MS patients with a mean age SD of 38 66 9 9 years were recruited in this study Of them 1216 78 1 were female The majority of patients 300 patients 19 3 were in the age range 35 39 years and the highest prevalence 184 82 per 100 000 populations was observed in the age range 40 44 years The prevalence of MS in Kermanshah province is estimated 79 50 per 100 000 people 125 71 per 100 000 in female and 34 41 per 100 000 in male This prevalence was higher in female female to male was 3 65 to 1 The EDSS score was significantly higher in male than in female 3 06 2 2 in male versus 2 42 1 8 in female p 0 001 The type of MS was significantly different between male and female so that SPMS and PPMS were more common in male 31 10 3 22 7 3 than female 81 7 5 39 3 6 p 0 012 A positive family history of MS was found in 12 6 of patients Conclusion Given the information about prevalence of MS in Kermanshah in 2012 the prevalence of MS in Kermanshah has increased during last decade MS disabilities were more extensive in male rather than female 2021 Elsevier B V
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