Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement.

Knauert, MP; Ayas, NT; Bosma, KJ; Drouot, X; Heavner, MS; Owens, RL; Watson, PL; Wilcox, ME; Anderson, BJ; Cordoza, ML; Devlin, JW; Elliott, R; Gehlbach, BK; Girard, TD; Kamdar, BB; Korwin, AS; Lusczek, ER; Parthasarathy, S; Spies, C; Sunderram, J; Telias, I; Weinhouse, GL; Zee, PC

Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement.

Knauert, MP Ayas, NT Bosma, KJ Drouot, X Heavner, MS Owens, RL Watson, PL Wilcox, ME Anderson, BJ Cordoza, ML Devlin, JW Elliott, R

Gehlbach, BK Girard, TD Kamdar, BB Korwin, AS Lusczek, ER Parthasarathy, S Spies, C Sunderram, J Telias, I Weinhouse, GL Zee, PC

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Publisher:: American Thoracic Society
Publication Type:: Journal Article
Citation:: Am J Respir Crit Care Med, 2023, 207, (7), pp. e49-e68
Issue Date:: 2023-04-01

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Field	Value	Language
dc.contributor.author	Knauert, MP
dc.contributor.author	Ayas, NT
dc.contributor.author	Bosma, KJ
dc.contributor.author	Drouot, X
dc.contributor.author	Heavner, MS
dc.contributor.author	Owens, RL
dc.contributor.author	Watson, PL
dc.contributor.author	Wilcox, ME
dc.contributor.author	Anderson, BJ
dc.contributor.author	Cordoza, ML
dc.contributor.author	Devlin, JW
dc.contributor.author	Elliott, R https://orcid.org/0000-0002-9239-7126
dc.contributor.author	Gehlbach, BK
dc.contributor.author	Girard, TD
dc.contributor.author	Kamdar, BB
dc.contributor.author	Korwin, AS
dc.contributor.author	Lusczek, ER
dc.contributor.author	Parthasarathy, S
dc.contributor.author	Spies, C
dc.contributor.author	Sunderram, J
dc.contributor.author	Telias, I
dc.contributor.author	Weinhouse, GL
dc.contributor.author	Zee, PC
dc.date.accessioned	2023-09-13T06:47:03Z
dc.date.available	2023-09-13T06:47:03Z
dc.date.issued	2023-04-01
dc.identifier.citation	Am J Respir Crit Care Med, 2023, 207, (7), pp. e49-e68
dc.identifier.issn	1073-449X
dc.identifier.issn	1535-4970
dc.identifier.uri	http://hdl.handle.net/10453/172082
dc.description.abstract	Background: Sleep and circadian disruption (SCD) is common and severe in the ICU. On the basis of rigorous evidence in non-ICU populations and emerging evidence in ICU populations, SCD is likely to have a profound negative impact on patient outcomes. Thus, it is urgent that we establish research priorities to advance understanding of ICU SCD. Methods: We convened a multidisciplinary group with relevant expertise to participate in an American Thoracic Society Workshop. Workshop objectives included identifying ICU SCD subtopics of interest, key knowledge gaps, and research priorities. Members attended remote sessions from March to November 2021. Recorded presentations were prepared and viewed by members before Workshop sessions. Workshop discussion focused on key gaps and related research priorities. The priorities listed herein were selected on the basis of rank as established by a series of anonymous surveys. Results: We identified the following research priorities: establish an ICU SCD definition, further develop rigorous and feasible ICU SCD measures, test associations between ICU SCD domains and outcomes, promote the inclusion of mechanistic and patient-centered outcomes within large clinical studies, leverage implementation science strategies to maximize intervention fidelity and sustainability, and collaborate among investigators to harmonize methods and promote multisite investigation. Conclusions: ICU SCD is a complex and compelling potential target for improving ICU outcomes. Given the influence on all other research priorities, further development of rigorous, feasible ICU SCD measurement is a key next step in advancing the field.
dc.format	Print
dc.language	eng
dc.publisher	American Thoracic Society
dc.relation.ispartof	Am J Respir Crit Care Med
dc.relation.isbasedon	10.1164/rccm.202301-0184ST
dc.rights	info:eu-repo/semantics/embargoedAccess
dc.subject	11 Medical and Health Sciences
dc.subject.classification	Respiratory System
dc.subject.classification	3201 Cardiovascular medicine and haematology
dc.subject.classification	3202 Clinical sciences
dc.subject.mesh	Humans
dc.subject.mesh	United States
dc.subject.mesh	Sleep
dc.subject.mesh	Polysomnography
dc.subject.mesh	Societies, Medical
dc.subject.mesh	Humans
dc.subject.mesh	Polysomnography
dc.subject.mesh	Sleep
dc.subject.mesh	Societies, Medical
dc.subject.mesh	United States
dc.subject.mesh	Humans
dc.subject.mesh	United States
dc.subject.mesh	Sleep
dc.subject.mesh	Polysomnography
dc.subject.mesh	Societies, Medical
dc.title	Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement.
dc.type	Journal Article
utslib.citation.volume	207
utslib.location.activity	United States
utslib.for	11 Medical and Health Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
utslib.copyright.embargo	2024-04-01T00:00:00+1000Z
dc.date.updated	2023-09-13T06:46:58Z
pubs.issue	7
pubs.publication-status	Published
pubs.volume	207
utslib.citation.issue	7

Abstract:

Background: Sleep and circadian disruption (SCD) is common and severe in the ICU. On the basis of rigorous evidence in non-ICU populations and emerging evidence in ICU populations, SCD is likely to have a profound negative impact on patient outcomes. Thus, it is urgent that we establish research priorities to advance understanding of ICU SCD. Methods: We convened a multidisciplinary group with relevant expertise to participate in an American Thoracic Society Workshop. Workshop objectives included identifying ICU SCD subtopics of interest, key knowledge gaps, and research priorities. Members attended remote sessions from March to November 2021. Recorded presentations were prepared and viewed by members before Workshop sessions. Workshop discussion focused on key gaps and related research priorities. The priorities listed herein were selected on the basis of rank as established by a series of anonymous surveys. Results: We identified the following research priorities: establish an ICU SCD definition, further develop rigorous and feasible ICU SCD measures, test associations between ICU SCD domains and outcomes, promote the inclusion of mechanistic and patient-centered outcomes within large clinical studies, leverage implementation science strategies to maximize intervention fidelity and sustainability, and collaborate among investigators to harmonize methods and promote multisite investigation. Conclusions: ICU SCD is a complex and compelling potential target for improving ICU outcomes. Given the influence on all other research priorities, further development of rigorous, feasible ICU SCD measurement is a key next step in advancing the field.

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http://hdl.handle.net/10453/172082