Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study.

Dell'Aquila, A; Berle, D

Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study.

Dell'Aquila, A Berle, D

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Publisher:: Springer Nature
Publication Type:: Journal Article
Citation:: Soc Psychiatry Psychiatr Epidemiol, 2023, 58, (10), pp. 1509-1522
Issue Date:: 2023-10

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Field	Value	Language
dc.contributor.author	Dell'Aquila, A
dc.contributor.author	Berle, D https://orcid.org/0000-0002-4861-2220
dc.date.accessioned	2023-09-14T02:45:59Z
dc.date.available	2023-03-30
dc.date.available	2023-09-14T02:45:59Z
dc.date.issued	2023-10
dc.identifier.citation	Soc Psychiatry Psychiatr Epidemiol, 2023, 58, (10), pp. 1509-1522
dc.identifier.issn	0933-7954
dc.identifier.issn	1433-9285
dc.identifier.uri	http://hdl.handle.net/10453/172092
dc.description.abstract	PURPOSE: The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD. METHODS: We analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms. RESULTS: Individuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD. CONCLUSIONS: Interpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highlight the importance of ensuring services and support for interpersonal trauma survivors and for those who have experienced multiple traumas given their increased for unfavourable outcomes.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Springer Nature
dc.relation.ispartof	Soc Psychiatry Psychiatr Epidemiol
dc.relation.isbasedon	10.1007/s00127-023-02472-6
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1103 Clinical Sciences, 1701 Psychology, 1702 Cognitive Sciences
dc.subject.classification	Psychiatry
dc.subject.classification	4202 Epidemiology
dc.subject.classification	4206 Public health
dc.subject.classification	5203 Clinical and health psychology
dc.subject.mesh	Adult
dc.subject.mesh	Humans
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Stress Disorders, Post-Traumatic
dc.subject.mesh	Substance-Related Disorders
dc.subject.mesh	Alcohol-Related Disorders
dc.subject.mesh	Alcoholism
dc.subject.mesh	Alcohol Drinking
dc.subject.mesh	Humans
dc.subject.mesh	Substance-Related Disorders
dc.subject.mesh	Alcohol-Related Disorders
dc.subject.mesh	Alcoholism
dc.subject.mesh	Alcohol Drinking
dc.subject.mesh	Stress Disorders, Post-Traumatic
dc.subject.mesh	Adult
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.title	Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study.
dc.type	Journal Article
utslib.citation.volume	58
utslib.location.activity	Germany
utslib.for	1103 Clinical Sciences
utslib.for	1701 Psychology
utslib.for	1702 Cognitive Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
dc.date.updated	2023-09-14T02:45:56Z
pubs.issue	10
pubs.publication-status	Published
pubs.volume	58
utslib.citation.issue	10

Abstract:

PURPOSE: The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD. METHODS: We analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms. RESULTS: Individuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD. CONCLUSIONS: Interpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highlight the importance of ensuring services and support for interpersonal trauma survivors and for those who have experienced multiple traumas given their increased for unfavourable outcomes.

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http://hdl.handle.net/10453/172092