Predictors of the survival of gastric cancer patients diagnosed at Bhaktapur Cancer Hospital, Nepal – A retrospective cohort study

Poudel, Krishna Kanta

Predictors of the survival of gastric cancer patients diagnosed at Bhaktapur Cancer Hospital, Nepal – A retrospective cohort study

Poudel, Krishna Kanta

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Publication Type:: Thesis
Issue Date:: 2022

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Field	Value	Language
dc.contributor.author	Poudel, Krishna Kanta
dc.date.accessioned	2023-10-17T02:58:04Z
dc.date.available	2023-10-17T02:58:04Z
dc.date.issued	2022
dc.identifier.uri	http://hdl.handle.net/10453/172722
dc.description	University of Technology Sydney. Faculty of Health.	en_US.UTF-8
dc.description.abstract	Gastric cancer was the fourth most common cause of cancer-related deaths worldwide in 2020. In Nepal, gastric cancer was the second most common cause of cancer deaths in males and the fifth most common cause of cancer deaths in females in 2020. Although gastric cancer is a significant public health problem, there have been no studies undertaken in Nepal to determine the survival and predictors of gastric cancer survival. This retrospective cohort study investigated the overall survival rate of people with gastric cancer and predictors of survival. We included 817 people who were diagnosed with gastric cancer between 1 January 2010 and 31 December 2021 at Bhaktapur Cancer Hospital, Nepal. The median overall survival for patients with gastric cancer was 19 months. The total person-time of follow-up was 17,808 months. Survival at one year was 70%, 37% at two-years, 23% at three-years, 18% at four- years, and 12% at five-years. Factors that affected survival included age, tumour locations, tumour stage at diagnosis, treatment by surgery, and treatment by chemotherapy. This study was limited by the data that was available in the routine medical records, however; to investigate additional potential predictors for survival of gastric cancer, and reduce survival bias, future research should include a prospective study design.	en_US.UTF-8
dc.format	Thesis (PhD)
dc.language.iso	en_US	en_US.UTF-8
dc.relation	https://opus.lib.uts.edu.au/bitstream/10453/172722/2/02whole.pdf
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	The author owns the copyright in this thesis including all reproduction and reuse rights for the work. The work may not be altered without the permission of the copyright owner. Attribution is essential when quoting or paraphrasing from this thesis.
dc.rights	© 2022 Krishna Kanta Poudel
dc.rights	au.edu.uts.lib/cph
dc.title	Predictors of the survival of gastric cancer patients diagnosed at Bhaktapur Cancer Hospital, Nepal – A retrospective cohort study	en_US.UTF-8
dc.type	Thesis
utslib.copyright.status	open_access	*

Abstract:

Gastric cancer was the fourth most common cause of cancer-related deaths worldwide in 2020. In Nepal, gastric cancer was the second most common cause of cancer deaths in males and the fifth most common cause of cancer deaths in females in 2020. Although gastric cancer is a significant public health problem, there have been no studies undertaken in Nepal to determine the survival and predictors of gastric cancer survival. This retrospective cohort study investigated the overall survival rate of people with gastric cancer and predictors of survival. We included 817 people who were diagnosed with gastric cancer between 1 January 2010 and 31 December 2021 at Bhaktapur Cancer Hospital, Nepal. The median overall survival for patients with gastric cancer was 19 months. The total person-time of follow-up was 17,808 months. Survival at one year was 70%, 37% at two-years, 23% at three-years, 18% at four- years, and 12% at five-years. Factors that affected survival included age, tumour locations, tumour stage at diagnosis, treatment by surgery, and treatment by chemotherapy. This study was limited by the data that was available in the routine medical records, however; to investigate additional potential predictors for survival of gastric cancer, and reduce survival bias, future research should include a prospective study design.

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http://hdl.handle.net/10453/172722