Keratoconus International Consortium (KIC)- advancing keratoconus research.

Sahebjada, S; Chan, E; Sutton, G; Pang, CPC; Srujana Sahebjada for KIC Members,; Kerdraon, Y; Natarajan, S; Meteoukki, W; Ang, A; Daniell, M; Baird, PN

Keratoconus International Consortium (KIC)- advancing keratoconus research.

Sahebjada, S Chan, E Sutton, G Pang, CPC Srujana Sahebjada for KIC Members, Kerdraon, Y Natarajan, S Meteoukki, W Ang, A Daniell, M Baird, PN

Permalink

Publisher:: Springer Nature
Publication Type:: Journal Article
Citation:: BMC Ophthalmol, 2023, 23, (1), pp. 337
Issue Date:: 2023-07-27

Open Access

Copyright Clearance Process

Recently Added
In Progress
Open Access

This item is open access.

Adobe PDF

Download Published versionAdobe PDF (1.18 MB)

View on publisher's site

View statistics

Full metadata record

Field	Value	Language
dc.contributor.author	Sahebjada, S
dc.contributor.author	Chan, E
dc.contributor.author	Sutton, G
dc.contributor.author	Pang, CPC
dc.contributor.author	Srujana Sahebjada for KIC Members,
dc.contributor.author	Kerdraon, Y
dc.contributor.author	Natarajan, S
dc.contributor.author	Meteoukki, W
dc.contributor.author	Ang, A
dc.contributor.author	Daniell, M
dc.contributor.author	Baird, PN
dc.date.accessioned	2024-01-04T03:06:06Z
dc.date.available	2023-07-16
dc.date.available	2024-01-04T03:06:06Z
dc.date.issued	2023-07-27
dc.identifier.citation	BMC Ophthalmol, 2023, 23, (1), pp. 337
dc.identifier.issn	1471-2415
dc.identifier.issn	1471-2415
dc.identifier.uri	http://hdl.handle.net/10453/173986
dc.description.abstract	CLINICAL RELEVANCE: The Keratoconus International Consortium (KIC) will allow better understanding of keratoconus. BACKGROUND: Keratoconus is a disorder characterised by corneal elevation and thinning, leading to reduced vision. The current gaps in understanding of this disease will be discussed and the need for a multi-pronged and multi-centre engagement to enhance our understanding of keratoconus will be highlighted. DESIGN: KIC has been established to address the gaps in our understanding of keratoconus with the aim of collecting baseline as well as longitudinal data on several fields. PARTICIPANTS: Keratoconus and control (no corneal condition) subjects from different sites globally will be recruited in the study. METHODS: KIC collects data using an online, secure database, which enables standardised data collection at member sites. Data fields collected include medical history, clinical features, quality of life and economic burden questionnaires and possible genetic sample collection from patients of different ethnicities across different geographical locations. RESULTS: There are currently 40 Australian and international clinics or hospital departments who have joined the KIC. Baseline data has so far been collected on 1130 keratoconus patients and indicates a median age of 29.70 years with 61% being male. A total of 15.3% report a positive family history of keratoconus and 57.7% self-report a history of frequent eye rubbing. CONCLUSION: The strength of this consortium is its international, collaborative design and use of a common data collection tool. Inclusion and analyses of cross-sectional and longitudinal data will help answer many questions that remain in keratoconus, including factors affecting progression and treatment outcomes.
dc.format	Electronic
dc.language	eng
dc.publisher	Springer Nature
dc.relation.ispartof	BMC Ophthalmol
dc.relation.isbasedon	10.1186/s12886-023-03087-w
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1113 Opthalmology and Optometry
dc.subject.classification	Ophthalmology & Optometry
dc.subject.classification	3212 Ophthalmology and optometry
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Adult
dc.subject.mesh	Female
dc.subject.mesh	Keratoconus
dc.subject.mesh	Quality of Life
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Australia
dc.subject.mesh	Cornea
dc.subject.mesh	Corneal Topography
dc.subject.mesh	Cornea
dc.subject.mesh	Humans
dc.subject.mesh	Keratoconus
dc.subject.mesh	Corneal Topography
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Quality of Life
dc.subject.mesh	Adult
dc.subject.mesh	Australia
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Adult
dc.subject.mesh	Female
dc.subject.mesh	Keratoconus
dc.subject.mesh	Quality of Life
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Australia
dc.subject.mesh	Cornea
dc.subject.mesh	Corneal Topography
dc.title	Keratoconus International Consortium (KIC)- advancing keratoconus research.
dc.type	Journal Article
utslib.citation.volume	23
utslib.location.activity	England
utslib.for	1113 Opthalmology and Optometry
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
dc.date.updated	2024-01-04T03:06:04Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	23
utslib.citation.issue	1

Abstract:

CLINICAL RELEVANCE: The Keratoconus International Consortium (KIC) will allow better understanding of keratoconus. BACKGROUND: Keratoconus is a disorder characterised by corneal elevation and thinning, leading to reduced vision. The current gaps in understanding of this disease will be discussed and the need for a multi-pronged and multi-centre engagement to enhance our understanding of keratoconus will be highlighted. DESIGN: KIC has been established to address the gaps in our understanding of keratoconus with the aim of collecting baseline as well as longitudinal data on several fields. PARTICIPANTS: Keratoconus and control (no corneal condition) subjects from different sites globally will be recruited in the study. METHODS: KIC collects data using an online, secure database, which enables standardised data collection at member sites. Data fields collected include medical history, clinical features, quality of life and economic burden questionnaires and possible genetic sample collection from patients of different ethnicities across different geographical locations. RESULTS: There are currently 40 Australian and international clinics or hospital departments who have joined the KIC. Baseline data has so far been collected on 1130 keratoconus patients and indicates a median age of 29.70 years with 61% being male. A total of 15.3% report a positive family history of keratoconus and 57.7% self-report a history of frequent eye rubbing. CONCLUSION: The strength of this consortium is its international, collaborative design and use of a common data collection tool. Inclusion and analyses of cross-sectional and longitudinal data will help answer many questions that remain in keratoconus, including factors affecting progression and treatment outcomes.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/173986