Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies.

Tavakoli, J; Diwan, AD; Tipper, JL

Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies.

Tavakoli, J

Diwan, AD Tipper, JL

Permalink

Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: Trends Biotechnol, 2023, 41, (11), pp. 1339-1342
Issue Date:: 2023-11

Closed Access

	Filename	Description	Size
	1-s2.0-S0167779923001300-main.pdf	Published version	927.27 kB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Tavakoli, J https://orcid.org/0000-0002-0696-6530
dc.contributor.author	Diwan, AD
dc.contributor.author	Tipper, JL
dc.date.accessioned	2024-02-29T06:54:22Z
dc.date.available	2023-04-24
dc.date.available	2024-02-29T06:54:22Z
dc.date.issued	2023-11
dc.identifier.citation	Trends Biotechnol, 2023, 41, (11), pp. 1339-1342
dc.identifier.issn	0167-7799
dc.identifier.issn	1879-3096
dc.identifier.uri	http://hdl.handle.net/10453/175987
dc.description.abstract	Current in vitro intervertebral disc (IVD) models do not fully recapitulate the complex mechanobiology of native tissue, and so far there is no strategy to effectively evaluate IVD regeneration. The development of a modular microfluidic on-chip model is expected to enhance the physiological relevance of experimental data leading to successful clinical outcomes.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Elsevier
dc.relation.ispartof	Trends Biotechnol
dc.relation.isbasedon	10.1016/j.tibtech.2023.04.009
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	06 Biological Sciences, 09 Engineering, 10 Technology
dc.subject.classification	Biotechnology
dc.subject.classification	3001 Agricultural biotechnology
dc.subject.classification	3106 Industrial biotechnology
dc.subject.classification	3206 Medical biotechnology
dc.title	Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies.
dc.type	Journal Article
utslib.citation.volume	41
utslib.location.activity	England
utslib.for	06 Biological Sciences
utslib.for	09 Engineering
utslib.for	10 Technology
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	University of Technology Sydney/Centre for Health Technologies (CHT)
utslib.copyright.status	closed_access	*
dc.date.updated	2024-02-29T06:54:21Z
pubs.issue	11
pubs.publication-status	Published
pubs.volume	41
utslib.citation.issue	11

Abstract:

Current in vitro intervertebral disc (IVD) models do not fully recapitulate the complex mechanobiology of native tissue, and so far there is no strategy to effectively evaluate IVD regeneration. The development of a modular microfluidic on-chip model is expected to enhance the physiological relevance of experimental data leading to successful clinical outcomes.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/175987