Non-Adherence to Anti-Retroviral Therapy Among Adult People Living with HIV in Ethiopia: Systematic Review and Meta-Analysis

Aytenew, TM; Demis, S; Birhane, BM; Asferie, WN; Simegn, A; Nibret, G; Kassaw, A; Asnakew, S; Tesfahun, Y; Andualem, H; Bantie, B; Kassaw, G; Kefale, D; Zeleke, S

Non-Adherence to Anti-Retroviral Therapy Among Adult People Living with HIV in Ethiopia: Systematic Review and Meta-Analysis

Aytenew, TM Demis, S Birhane, BM Asferie, WN Simegn, A Nibret, G Kassaw, A Asnakew, S Tesfahun, Y Andualem, H Bantie, B Kassaw, G Kefale, D Zeleke, S

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Publisher:: Springer Nature
Publication Type:: Journal Article
Citation:: AIDS and Behavior, 2024, 28, (2), pp. 609-624
Issue Date:: 2024-02

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Field	Value	Language
dc.contributor.author	Aytenew, TM
dc.contributor.author	Demis, S
dc.contributor.author	Birhane, BM
dc.contributor.author	Asferie, WN
dc.contributor.author	Simegn, A
dc.contributor.author	Nibret, G
dc.contributor.author	Kassaw, A
dc.contributor.author	Asnakew, S
dc.contributor.author	Tesfahun, Y
dc.contributor.author	Andualem, H
dc.contributor.author	Bantie, B
dc.contributor.author	Kassaw, G
dc.contributor.author	Kefale, D
dc.contributor.author	Zeleke, S
dc.date.accessioned	2024-07-24T07:30:03Z
dc.date.available	2023-12-08
dc.date.available	2024-07-24T07:30:03Z
dc.date.issued	2024-02
dc.identifier.citation	AIDS and Behavior, 2024, 28, (2), pp. 609-624
dc.identifier.issn	1090-7165
dc.identifier.issn	1573-3254
dc.identifier.uri	http://hdl.handle.net/10453/179830
dc.description.abstract	Human immunodeficiency virus remains a global public health problem Despite efforts to determine the prevalence of non adherence to ART and its predictors in Ethiopia various primary studies presented inconsistent findings Therefore this review aimed to determine the pooled prevalence of non adherence to ART and identify its predictors We have searched PubMed Google Scholar and Web of Science databases extensively for all available studies A weighted inverse variance random effects model was used to compute the overall non adherence to ART The pooled prevalence of non adherence to ART was 20 68 95 CI 17 74 23 61 I2 98 40 p 0 001 Educational level of primary school and lower AOR 3 5 95 CI 1 7 7 4 taking co medications AOR 0 45 95 CI 0 35 0 59 not using memory aids AOR 0 30 95 CI 0 13 0 71 depression AOR 2 0 95 CI 1 05 3 79 comorbidity AOR 2 12 95 CI 1 16 3 09 under nutrition AOR 2 02 95 CI 1 20 3 43 not believing on ART can control HIV AOR 2 31 95 CI 1 92 2 77 lack of access to health facilities AOR 3 86 95 CI 1 10 13 51 and taking ART pills uncomfortably while others looking AOR 5 21 95 CI 2 56 10 53 were significantly associated with non adherence to anti retroviral therapy The overall pooled prevalence of non adherence to ART was considerably high in Ethiopia Educational status taking co medications not using memory aids depression comorbidity under nutrition not believing on anti retroviral therapy controls HIV lack of access to health facilities and taking ART pills uncomfortably were independent predictors of non adherence to ART in Ethiopia Therefore healthcare providers adherence counselors and supporters should detect non adherence behaviors and patients difficulties with ART early and provide intensive counseling to promote adherence
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Springer Nature
dc.relation.ispartof	AIDS and Behavior
dc.relation.isbasedon	10.1007/s10461-023-04252-4
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	1117 Public Health and Health Services, 1607 Social Work
dc.subject.classification	Public Health
dc.subject.classification	4206 Public health
dc.subject.mesh	Adult
dc.subject.mesh	Humans
dc.subject.mesh	HIV Infections
dc.subject.mesh	HIV
dc.subject.mesh	Ethiopia
dc.subject.mesh	Counseling
dc.subject.mesh	Counselors
dc.subject.mesh	Humans
dc.subject.mesh	HIV
dc.subject.mesh	HIV Infections
dc.subject.mesh	Counseling
dc.subject.mesh	Adult
dc.subject.mesh	Ethiopia
dc.subject.mesh	Counselors
dc.subject.mesh	Adult
dc.subject.mesh	Humans
dc.subject.mesh	HIV Infections
dc.subject.mesh	HIV
dc.subject.mesh	Ethiopia
dc.subject.mesh	Counseling
dc.subject.mesh	Counselors
dc.title	Non-Adherence to Anti-Retroviral Therapy Among Adult People Living with HIV in Ethiopia: Systematic Review and Meta-Analysis
dc.type	Journal Article
utslib.citation.volume	28
utslib.location.activity	United States
utslib.for	1117 Public Health and Health Services
utslib.for	1607 Social Work
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Public Health
utslib.copyright.status	recently_added	*
pubs.consider-herdc	true
dc.date.updated	2024-07-24T07:29:51Z
pubs.issue	2
pubs.publication-status	Published
pubs.volume	28
utslib.citation.issue	2

Abstract:

Human immunodeficiency virus remains a global public health problem Despite efforts to determine the prevalence of non adherence to ART and its predictors in Ethiopia various primary studies presented inconsistent findings Therefore this review aimed to determine the pooled prevalence of non adherence to ART and identify its predictors We have searched PubMed Google Scholar and Web of Science databases extensively for all available studies A weighted inverse variance random effects model was used to compute the overall non adherence to ART The pooled prevalence of non adherence to ART was 20 68 95 CI 17 74 23 61 I2 98 40 p 0 001 Educational level of primary school and lower AOR 3 5 95 CI 1 7 7 4 taking co medications AOR 0 45 95 CI 0 35 0 59 not using memory aids AOR 0 30 95 CI 0 13 0 71 depression AOR 2 0 95 CI 1 05 3 79 comorbidity AOR 2 12 95 CI 1 16 3 09 under nutrition AOR 2 02 95 CI 1 20 3 43 not believing on ART can control HIV AOR 2 31 95 CI 1 92 2 77 lack of access to health facilities AOR 3 86 95 CI 1 10 13 51 and taking ART pills uncomfortably while others looking AOR 5 21 95 CI 2 56 10 53 were significantly associated with non adherence to anti retroviral therapy The overall pooled prevalence of non adherence to ART was considerably high in Ethiopia Educational status taking co medications not using memory aids depression comorbidity under nutrition not believing on anti retroviral therapy controls HIV lack of access to health facilities and taking ART pills uncomfortably were independent predictors of non adherence to ART in Ethiopia Therefore healthcare providers adherence counselors and supporters should detect non adherence behaviors and patients difficulties with ART early and provide intensive counseling to promote adherence

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http://hdl.handle.net/10453/179830