Inconclusiveness of psychometric testing of medication adherence questionnaires.

Arnet, I; Eickhoff, C; Sahm, LJ; Caloz, S; Mittag, M; Schulz, M; Allemann, SS

Inconclusiveness of psychometric testing of medication adherence questionnaires.

Arnet, I Eickhoff, C Sahm, LJ Caloz, S Mittag, M Schulz, M

Allemann, SS

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Publisher:: SPRINGER HEIDELBERG
Publication Type:: Journal Article
Citation:: Eur J Clin Pharmacol, 2024, 80, (8), pp. 1189-1195
Issue Date:: 2024-08

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Field	Value	Language
dc.contributor.author	Arnet, I
dc.contributor.author	Eickhoff, C
dc.contributor.author	Sahm, LJ
dc.contributor.author	Caloz, S
dc.contributor.author	Mittag, M
dc.contributor.author	Schulz, M https://orcid.org/0000-0002-5876-7322
dc.contributor.author	Allemann, SS
dc.date.accessioned	2024-07-24T07:38:29Z
dc.date.available	2024-03-27
dc.date.available	2024-07-24T07:38:29Z
dc.date.issued	2024-08
dc.identifier.citation	Eur J Clin Pharmacol, 2024, 80, (8), pp. 1189-1195
dc.identifier.issn	0031-6970
dc.identifier.issn	1432-1041
dc.identifier.uri	http://hdl.handle.net/10453/179833
dc.description.abstract	PURPOSE: To propose a paradigm change for the validation procedures of medication adherence questionnaires. METHODS: A total of 121 validation procedures of unique questionnaires for medication adherence were analyzed. RESULTS: "Construct validity" and "internal consistency" were most often assessed, and test results varied largely. A more in-depth analysis indicated that the assessment of medication non-adherence included distinct but related constructs, such as the extent to which doses are missed, and the attempt to identify different facets of medication-taking behavior. Consequently, each construct requires a different measurement approach with different psychometric tests for establishing its validity and reliability. CONCLUSION: Results show that assessing the validity and reliability of adherence questionnaires with standard procedures including statistical tests is inconclusive. Refinement of the constructs of non-adherence is needed in pharmacy and medical practice. We suggest a distinction between the (i) extent of missed doses over the past 2 weeks, (ii) modifiable reasons for non-adherence behavior, and (iii) unmodifiable factors of non-adherence. Validation procedures and corresponding statistical methods should be selected according to the specific single constructs.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	SPRINGER HEIDELBERG
dc.relation.ispartof	Eur J Clin Pharmacol
dc.relation.isbasedon	10.1007/s00228-024-03684-8
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences
dc.subject.classification	Pharmacology & Pharmacy
dc.subject.classification	3214 Pharmacology and pharmaceutical sciences
dc.subject.mesh	Psychometrics
dc.subject.mesh	Medication Adherence
dc.subject.mesh	Humans
dc.subject.mesh	Surveys and Questionnaires
dc.subject.mesh	Reproducibility of Results
dc.subject.mesh	Humans
dc.subject.mesh	Reproducibility of Results
dc.subject.mesh	Psychometrics
dc.subject.mesh	Medication Adherence
dc.subject.mesh	Surveys and Questionnaires
dc.subject.mesh	Psychometrics
dc.subject.mesh	Medication Adherence
dc.subject.mesh	Humans
dc.subject.mesh	Surveys and Questionnaires
dc.subject.mesh	Reproducibility of Results
dc.title	Inconclusiveness of psychometric testing of medication adherence questionnaires.
dc.type	Journal Article
utslib.citation.volume	80
utslib.location.activity	Germany
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
utslib.copyright.status	recently_added	*
dc.date.updated	2024-07-24T07:38:25Z
pubs.issue	8
pubs.publication-status	Published
pubs.volume	80
utslib.citation.issue	8

Abstract:

PURPOSE: To propose a paradigm change for the validation procedures of medication adherence questionnaires. METHODS: A total of 121 validation procedures of unique questionnaires for medication adherence were analyzed. RESULTS: "Construct validity" and "internal consistency" were most often assessed, and test results varied largely. A more in-depth analysis indicated that the assessment of medication non-adherence included distinct but related constructs, such as the extent to which doses are missed, and the attempt to identify different facets of medication-taking behavior. Consequently, each construct requires a different measurement approach with different psychometric tests for establishing its validity and reliability. CONCLUSION: Results show that assessing the validity and reliability of adherence questionnaires with standard procedures including statistical tests is inconclusive. Refinement of the constructs of non-adherence is needed in pharmacy and medical practice. We suggest a distinction between the (i) extent of missed doses over the past 2 weeks, (ii) modifiable reasons for non-adherence behavior, and (iii) unmodifiable factors of non-adherence. Validation procedures and corresponding statistical methods should be selected according to the specific single constructs.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/179833