Comorbid depression among adults with heart failure in Ethiopia: a hospital-based cross-sectional study.
- Publisher:
- BMC
- Publication Type:
- Journal Article
- Citation:
- BMC Psychiatry, 2024, 24, (1), pp. 321
- Issue Date:
- 2024-04-25
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Field | Value | Language |
---|---|---|
dc.contributor.author | Mulugeta, H | |
dc.contributor.author | Sinclair, PM | |
dc.contributor.author |
Wilson, A |
|
dc.date.accessioned | 2024-08-01T04:33:32Z | |
dc.date.available | 2024-04-08 | |
dc.date.available | 2024-08-01T04:33:32Z | |
dc.date.issued | 2024-04-25 | |
dc.identifier.citation | BMC Psychiatry, 2024, 24, (1), pp. 321 | |
dc.identifier.issn | 1471-244X | |
dc.identifier.issn | 1471-244X | |
dc.identifier.uri | http://hdl.handle.net/10453/179940 | |
dc.description.abstract | BACKGROUND: Depression is a common comorbidity in adults with heart failure. It is associated with poor clinical outcomes, including decreased health-related quality of life and increased morbidity and mortality. There is a lack of data concerning the extent of this issue in Ethiopia. Consequently, this study aimed to assess the prevalence of comorbid depression and associated factors among adults living with heart failure in Ethiopia. METHODS: A hospital-based cross-sectional study was conducted at the cardiac outpatient clinics of two selected specialist public hospitals in Addis Ababa, Ethiopia: St. Paul's Hospital Millennium Medical College and St. Peter Specialized Hospital. An interviewer-administered questionnaire was used to collect data from 383 adults with heart failure who attended the clinics and met the inclusion criteria. Depression was measured using the Patient Health Questionnaire (PHQ-9). A binary logistic regression model was fitted to identify factors associated with depression. All statistical analyses were conducted using STATA version 17 software. RESULTS: The mean age of the participants was 55 years. On average, participants had moderate depression, as indicated by the mean PHQ-9 score of 11.02 ± 6.14, and 217 (56.6%, 95%CI 51.53-61.68) had comorbid depression. Significant associations with depression were observed among participants who were female (AOR: 2.31, 95%CI:1.30-4.08), had comorbid diabetes mellitus (AOR: 3.16, 95%CI: 1.47-6.82), were classified as New York Heart Association (NYHA) class IV (AOR: 3.59, 95%CI: 1.05-12.30), reported poor levels of social support (AOR: 6.04, 95%CI: 2.97-12.32), and took more than five medications per day (AOR: 5.26, 95%CI: 2.72-10.18). CONCLUSIONS: This study indicates that over half of all adults with heart failure in Ethiopia have comorbid depression, influenced by several factors. The findings have significant implications in terms of treatment outcomes and quality of life. More research in the area, including interventional and qualitative studies, and consideration of multifaceted approaches, such as psychosocial interventions, are needed to reduce the burden of comorbid depression in this population. | |
dc.format | Electronic | |
dc.language | eng | |
dc.publisher | BMC | |
dc.relation.ispartof | BMC Psychiatry | |
dc.relation.isbasedon | 10.1186/s12888-024-05748-6 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | 1103 Clinical Sciences, 1117 Public Health and Health Services, 1701 Psychology | |
dc.subject.classification | Psychiatry | |
dc.subject.classification | 3202 Clinical sciences | |
dc.subject.classification | 4202 Epidemiology | |
dc.subject.classification | 5203 Clinical and health psychology | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Ethiopia | |
dc.subject.mesh | Female | |
dc.subject.mesh | Heart Failure | |
dc.subject.mesh | Male | |
dc.subject.mesh | Cross-Sectional Studies | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Comorbidity | |
dc.subject.mesh | Adult | |
dc.subject.mesh | Prevalence | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Depression | |
dc.subject.mesh | Quality of Life | |
dc.subject.mesh | Depressive Disorder | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Prevalence | |
dc.subject.mesh | Cross-Sectional Studies | |
dc.subject.mesh | Depression | |
dc.subject.mesh | Depressive Disorder | |
dc.subject.mesh | Comorbidity | |
dc.subject.mesh | Quality of Life | |
dc.subject.mesh | Adult | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Ethiopia | |
dc.subject.mesh | Female | |
dc.subject.mesh | Male | |
dc.subject.mesh | Heart Failure | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Ethiopia | |
dc.subject.mesh | Female | |
dc.subject.mesh | Heart Failure | |
dc.subject.mesh | Male | |
dc.subject.mesh | Cross-Sectional Studies | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Comorbidity | |
dc.subject.mesh | Adult | |
dc.subject.mesh | Prevalence | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Depression | |
dc.subject.mesh | Quality of Life | |
dc.subject.mesh | Depressive Disorder | |
dc.title | Comorbid depression among adults with heart failure in Ethiopia: a hospital-based cross-sectional study. | |
dc.type | Journal Article | |
utslib.citation.volume | 24 | |
utslib.location.activity | England | |
utslib.for | 1103 Clinical Sciences | |
utslib.for | 1117 Public Health and Health Services | |
utslib.for | 1701 Psychology | |
pubs.organisational-group | University of Technology Sydney | |
pubs.organisational-group | University of Technology Sydney/Faculty of Health | |
utslib.copyright.status | open_access | * |
dc.rights.license | This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/ | |
dc.date.updated | 2024-08-01T04:33:31Z | |
pubs.issue | 1 | |
pubs.publication-status | Published online | |
pubs.volume | 24 | |
utslib.citation.issue | 1 |
Abstract:
BACKGROUND: Depression is a common comorbidity in adults with heart failure. It is associated with poor clinical outcomes, including decreased health-related quality of life and increased morbidity and mortality. There is a lack of data concerning the extent of this issue in Ethiopia. Consequently, this study aimed to assess the prevalence of comorbid depression and associated factors among adults living with heart failure in Ethiopia. METHODS: A hospital-based cross-sectional study was conducted at the cardiac outpatient clinics of two selected specialist public hospitals in Addis Ababa, Ethiopia: St. Paul's Hospital Millennium Medical College and St. Peter Specialized Hospital. An interviewer-administered questionnaire was used to collect data from 383 adults with heart failure who attended the clinics and met the inclusion criteria. Depression was measured using the Patient Health Questionnaire (PHQ-9). A binary logistic regression model was fitted to identify factors associated with depression. All statistical analyses were conducted using STATA version 17 software. RESULTS: The mean age of the participants was 55 years. On average, participants had moderate depression, as indicated by the mean PHQ-9 score of 11.02 ± 6.14, and 217 (56.6%, 95%CI 51.53-61.68) had comorbid depression. Significant associations with depression were observed among participants who were female (AOR: 2.31, 95%CI:1.30-4.08), had comorbid diabetes mellitus (AOR: 3.16, 95%CI: 1.47-6.82), were classified as New York Heart Association (NYHA) class IV (AOR: 3.59, 95%CI: 1.05-12.30), reported poor levels of social support (AOR: 6.04, 95%CI: 2.97-12.32), and took more than five medications per day (AOR: 5.26, 95%CI: 2.72-10.18). CONCLUSIONS: This study indicates that over half of all adults with heart failure in Ethiopia have comorbid depression, influenced by several factors. The findings have significant implications in terms of treatment outcomes and quality of life. More research in the area, including interventional and qualitative studies, and consideration of multifaceted approaches, such as psychosocial interventions, are needed to reduce the burden of comorbid depression in this population.
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