Learning together for better health using an evidence-based Learning Health System framework: a case study in stroke.

Teede, H; Cadilhac, DA; Purvis, T; Kilkenny, MF; Campbell, BCV; English, C; Johnson, A; Callander, E; Grimley, RS; Levi, C; Middleton, S; Hill, K; Enticott, J

Learning together for better health using an evidence-based Learning Health System framework: a case study in stroke.

Teede, H Cadilhac, DA Purvis, T Kilkenny, MF Campbell, BCV English, C Johnson, A Callander, E

Grimley, RS Levi, C Middleton, S Hill, K Enticott, J

Permalink

Publisher:: BMC
Publication Type:: Journal Article
Citation:: BMC Med, 2024, 22, (1), pp. 198
Issue Date:: 2024-05-15

Open Access

Copyright Clearance Process

Recently Added
In Progress
Open Access

This item is open access.

Adobe PDF

Download Published versionAdobe PDF (1.74 MB)

View on publisher's site

View statistics

Full metadata record

Field	Value	Language
dc.contributor.author	Teede, H
dc.contributor.author	Cadilhac, DA
dc.contributor.author	Purvis, T
dc.contributor.author	Kilkenny, MF
dc.contributor.author	Campbell, BCV
dc.contributor.author	English, C
dc.contributor.author	Johnson, A
dc.contributor.author	Callander, E https://orcid.org/0000-0001-7233-6804
dc.contributor.author	Grimley, RS
dc.contributor.author	Levi, C
dc.contributor.author	Middleton, S
dc.contributor.author	Hill, K
dc.contributor.author	Enticott, J
dc.date.accessioned	2024-08-01T04:38:54Z
dc.date.available	2024-04-30
dc.date.available	2024-08-01T04:38:54Z
dc.date.issued	2024-05-15
dc.identifier.citation	BMC Med, 2024, 22, (1), pp. 198
dc.identifier.issn	1741-7015
dc.identifier.issn	1741-7015
dc.identifier.uri	http://hdl.handle.net/10453/179950
dc.description.abstract	BACKGROUND: In the context of expanding digital health tools, the health system is ready for Learning Health System (LHS) models. These models, with proper governance and stakeholder engagement, enable the integration of digital infrastructure to provide feedback to all relevant parties including clinicians and consumers on performance against best practice standards, as well as fostering innovation and aligning healthcare with patient needs. The LHS literature primarily includes opinion or consensus-based frameworks and lacks validation or evidence of benefit. Our aim was to outline a rigorously codesigned, evidence-based LHS framework and present a national case study of an LHS-aligned national stroke program that has delivered clinical benefit. MAIN TEXT: Current core components of a LHS involve capturing evidence from communities and stakeholders (quadrant 1), integrating evidence from research findings (quadrant 2), leveraging evidence from data and practice (quadrant 3), and generating evidence from implementation (quadrant 4) for iterative system-level improvement. The Australian Stroke program was selected as the case study as it provides an exemplar of how an iterative LHS works in practice at a national level encompassing and integrating evidence from all four LHS quadrants. Using this case study, we demonstrate how to apply evidence-based processes to healthcare improvement and embed real-world research for optimising healthcare improvement. We emphasize the transition from research as an endpoint, to research as an enabler and a solution for impact in healthcare improvement. CONCLUSIONS: The Australian Stroke program has nationally improved stroke care since 2007, showcasing the value of integrated LHS-aligned approaches for tangible impact on outcomes. This LHS case study is a practical example for other health conditions and settings to follow suit.
dc.format	Electronic
dc.language	eng
dc.publisher	BMC
dc.relation.ispartof	BMC Med
dc.relation.isbasedon	10.1186/s12916-024-03416-w
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	11 Medical and Health Sciences
dc.subject.classification	General & Internal Medicine
dc.subject.classification	32 Biomedical and clinical sciences
dc.subject.classification	42 Health sciences
dc.subject.mesh	Humans
dc.subject.mesh	Learning Health System
dc.subject.mesh	Stroke
dc.subject.mesh	Australia
dc.subject.mesh	Evidence-Based Medicine
dc.subject.mesh	Evidence-Based Practice
dc.subject.mesh	Humans
dc.subject.mesh	Evidence-Based Medicine
dc.subject.mesh	Australia
dc.subject.mesh	Stroke
dc.subject.mesh	Evidence-Based Practice
dc.subject.mesh	Learning Health System
dc.subject.mesh	Humans
dc.subject.mesh	Learning Health System
dc.subject.mesh	Stroke
dc.subject.mesh	Australia
dc.subject.mesh	Evidence-Based Medicine
dc.subject.mesh	Evidence-Based Practice
dc.title	Learning together for better health using an evidence-based Learning Health System framework: a case study in stroke.
dc.type	Journal Article
utslib.citation.volume	22
utslib.location.activity	England
utslib.for	11 Medical and Health Sciences
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/
dc.date.updated	2024-08-01T04:38:53Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	22
utslib.citation.issue	1

Abstract:

BACKGROUND: In the context of expanding digital health tools, the health system is ready for Learning Health System (LHS) models. These models, with proper governance and stakeholder engagement, enable the integration of digital infrastructure to provide feedback to all relevant parties including clinicians and consumers on performance against best practice standards, as well as fostering innovation and aligning healthcare with patient needs. The LHS literature primarily includes opinion or consensus-based frameworks and lacks validation or evidence of benefit. Our aim was to outline a rigorously codesigned, evidence-based LHS framework and present a national case study of an LHS-aligned national stroke program that has delivered clinical benefit. MAIN TEXT: Current core components of a LHS involve capturing evidence from communities and stakeholders (quadrant 1), integrating evidence from research findings (quadrant 2), leveraging evidence from data and practice (quadrant 3), and generating evidence from implementation (quadrant 4) for iterative system-level improvement. The Australian Stroke program was selected as the case study as it provides an exemplar of how an iterative LHS works in practice at a national level encompassing and integrating evidence from all four LHS quadrants. Using this case study, we demonstrate how to apply evidence-based processes to healthcare improvement and embed real-world research for optimising healthcare improvement. We emphasize the transition from research as an endpoint, to research as an enabler and a solution for impact in healthcare improvement. CONCLUSIONS: The Australian Stroke program has nationally improved stroke care since 2007, showcasing the value of integrated LHS-aligned approaches for tangible impact on outcomes. This LHS case study is a practical example for other health conditions and settings to follow suit.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/179950