Applications of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration.
- Publisher:
- MDPI
- Publication Type:
- Journal Article
- Citation:
- Int J Mol Sci, 2024, 25, (11), pp. 5863
- Issue Date:
- 2024-05-28
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Full metadata record
| Field | Value | Language |
|---|---|---|
| dc.contributor.author | Yavuz, B | |
| dc.contributor.author | Mutlu, EC | |
| dc.contributor.author | Ahmed, Z | |
| dc.contributor.author | Ben-Nissan, B | |
| dc.contributor.author | Stamboulis, A | |
| dc.date.accessioned | 2024-08-02T02:40:30Z | |
| dc.date.available | 2024-05-23 | |
| dc.date.available | 2024-08-02T02:40:30Z | |
| dc.date.issued | 2024-05-28 | |
| dc.identifier.citation | Int J Mol Sci, 2024, 25, (11), pp. 5863 | |
| dc.identifier.issn | 1422-0067 | |
| dc.identifier.issn | 1422-0067 | |
| dc.identifier.uri | http://hdl.handle.net/10453/179992 | |
| dc.description.abstract | Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopaedic surgery cases. This review explores the involvement of EVs in nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-free therapies. It underscores the importance of bioengineers comprehending and manipulating EV activity to optimize the efficacy of tissue engineering and regenerative therapies. | |
| dc.format | Electronic | |
| dc.language | eng | |
| dc.publisher | MDPI | |
| dc.relation.ispartof | Int J Mol Sci | |
| dc.relation.isbasedon | 10.3390/ijms25115863 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | 0399 Other Chemical Sciences, 0604 Genetics, 0699 Other Biological Sciences | |
| dc.subject.classification | Chemical Physics | |
| dc.subject.classification | 3101 Biochemistry and cell biology | |
| dc.subject.classification | 3107 Microbiology | |
| dc.subject.classification | 3404 Medicinal and biomolecular chemistry | |
| dc.subject.mesh | Nerve Regeneration | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Extracellular Vesicles | |
| dc.subject.mesh | Animals | |
| dc.subject.mesh | Stem Cells | |
| dc.subject.mesh | Tissue Engineering | |
| dc.subject.mesh | Exosomes | |
| dc.subject.mesh | Regenerative Medicine | |
| dc.subject.mesh | Stem Cells | |
| dc.subject.mesh | Animals | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Tissue Engineering | |
| dc.subject.mesh | Regenerative Medicine | |
| dc.subject.mesh | Nerve Regeneration | |
| dc.subject.mesh | Exosomes | |
| dc.subject.mesh | Extracellular Vesicles | |
| dc.subject.mesh | Nerve Regeneration | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Extracellular Vesicles | |
| dc.subject.mesh | Animals | |
| dc.subject.mesh | Stem Cells | |
| dc.subject.mesh | Tissue Engineering | |
| dc.subject.mesh | Exosomes | |
| dc.subject.mesh | Regenerative Medicine | |
| dc.title | Applications of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration. | |
| dc.type | Journal Article | |
| utslib.citation.volume | 25 | |
| utslib.location.activity | Switzerland | |
| utslib.for | 0399 Other Chemical Sciences | |
| utslib.for | 0604 Genetics | |
| utslib.for | 0699 Other Biological Sciences | |
| pubs.organisational-group | University of Technology Sydney | |
| pubs.organisational-group | University of Technology Sydney/Faculty of Science | |
| pubs.organisational-group | University of Technology Sydney/Strength - CHT - Health Technologies | |
| pubs.organisational-group | University of Technology Sydney/All Manual Groups | |
| pubs.organisational-group | University of Technology Sydney/All Manual Groups/Centre for Health Technologies (CHT) | |
| utslib.copyright.status | open_access | * |
| dc.rights.license | This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/ | |
| dc.date.updated | 2024-08-02T02:40:25Z | |
| pubs.issue | 11 | |
| pubs.publication-status | Published online | |
| pubs.volume | 25 | |
| utslib.citation.issue | 11 |
Abstract:
Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopaedic surgery cases. This review explores the involvement of EVs in nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-free therapies. It underscores the importance of bioengineers comprehending and manipulating EV activity to optimize the efficacy of tissue engineering and regenerative therapies.
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