The parasitic lifestyle of an archaeal symbiont.

Hamm, JN; Liao, Y; von Kügelgen, A; Dombrowski, N; Landers, E; Brownlee, C; Johansson, EMV; Whan, RM; Baker, MAB; Baum, B; Bharat, TAM; Duggin, IG; Spang, A; Cavicchioli, R

The parasitic lifestyle of an archaeal symbiont.

Hamm, JN Liao, Y

von Kügelgen, A Dombrowski, N Landers, E Brownlee, C Johansson, EMV Whan, RM Baker, MAB Baum, B Bharat, TAM Duggin, IG Spang, A Cavicchioli, R

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Publisher:: NATURE PORTFOLIO
Publication Type:: Journal Article
Citation:: Nat Commun, 2024, 15, (1), pp. 6449
Issue Date:: 2024-07-31

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Field	Value	Language
dc.contributor.author	Hamm, JN
dc.contributor.author	Liao, Y https://orcid.org/0000-0002-8492-2648
dc.contributor.author	von Kügelgen, A
dc.contributor.author	Dombrowski, N
dc.contributor.author	Landers, E
dc.contributor.author	Brownlee, C
dc.contributor.author	Johansson, EMV
dc.contributor.author	Whan, RM
dc.contributor.author	Baker, MAB
dc.contributor.author	Baum, B
dc.contributor.author	Bharat, TAM
dc.contributor.author	Duggin, IG
dc.contributor.author	Spang, A
dc.contributor.author	Cavicchioli, R
dc.date.accessioned	2024-08-21T03:45:59Z
dc.date.available	2024-06-25
dc.date.available	2024-08-21T03:45:59Z
dc.date.issued	2024-07-31
dc.identifier.citation	Nat Commun, 2024, 15, (1), pp. 6449
dc.identifier.issn	2041-1723
dc.identifier.issn	2041-1723
dc.identifier.uri	http://hdl.handle.net/10453/180445
dc.description.abstract	DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology.
dc.format	Electronic
dc.language	eng
dc.publisher	NATURE PORTFOLIO
dc.relation	http://purl.org/au-research/grants/arc/FT160100010
dc.relation.ispartof	Nat Commun
dc.relation.isbasedon	10.1038/s41467-024-49962-y
dc.rights	info:eu-repo/semantics/openAccess
dc.subject.mesh	Symbiosis
dc.subject.mesh	Halorubrum
dc.subject.mesh	Archaea
dc.subject.mesh	Nanoarchaeota
dc.subject.mesh	Genome, Archaeal
dc.subject.mesh	Phylogeny
dc.subject.mesh	Archaea
dc.subject.mesh	Nanoarchaeota
dc.subject.mesh	Phylogeny
dc.subject.mesh	Symbiosis
dc.subject.mesh	Genome, Archaeal
dc.subject.mesh	Halorubrum
dc.title	The parasitic lifestyle of an archaeal symbiont.
dc.type	Journal Article
utslib.citation.volume	15
utslib.location.activity	England
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Science
pubs.organisational-group	University of Technology Sydney/Strength - AIMI - Australian Institute for Microbiology & Infection
pubs.organisational-group	University of Technology Sydney/All Manual Groups
pubs.organisational-group	University of Technology Sydney/All Manual Groups/Australian Institute for Microbiology & Infection (AIMI)
pubs.organisational-group	University of Technology Sydney/All Manual Groups/Australian Institute for Microbiology & Infection (AIMI)/Associate Member
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/
dc.date.updated	2024-08-21T03:45:54Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	15
utslib.citation.issue	1

Abstract:

DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology.

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http://hdl.handle.net/10453/180445