Top Ten Tips Palliative Care Clinicians Should Know About Interpreting a Clinical Trial.

Gurgenci, T; O'Leary, C; Hui, D; Yennu, S; Bruera, E; Davis, M; Agar, MR; Zimmermann, C; Philip, J; Mercadante, S; Hardy, J; Rosa, WE; Good, P

Top Ten Tips Palliative Care Clinicians Should Know About Interpreting a Clinical Trial.

Gurgenci, T O'Leary, C Hui, D Yennu, S Bruera, E Davis, M Agar, MR Zimmermann, C Philip, J Mercadante, S Hardy, J Rosa, WE Good, P

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Publisher:: MARY ANN LIEBERT, INC
Publication Type:: Journal Article
Citation:: J Palliat Med, 2024
Issue Date:: 2024-07-24

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Field	Value	Language
dc.contributor.author	Gurgenci, T
dc.contributor.author	O'Leary, C
dc.contributor.author	Hui, D
dc.contributor.author	Yennu, S
dc.contributor.author	Bruera, E
dc.contributor.author	Davis, M
dc.contributor.author	Agar, MR
dc.contributor.author	Zimmermann, C
dc.contributor.author	Philip, J
dc.contributor.author	Mercadante, S
dc.contributor.author	Hardy, J
dc.contributor.author	Rosa, WE
dc.contributor.author	Good, P https://orcid.org/0000-0002-8198-0375
dc.date.accessioned	2024-10-03T06:55:47Z
dc.date.available	2024-10-03T06:55:47Z
dc.date.issued	2024-07-24
dc.identifier.citation	J Palliat Med, 2024
dc.identifier.issn	1096-6218
dc.identifier.issn	1557-7740
dc.identifier.uri	http://hdl.handle.net/10453/181172
dc.description.abstract	Evidence-based practice is foundational to high-quality palliative care delivery. However, the clinical trials that compose the evidence base are often methodologically imperfect. Applying their conclusions without critical application to the clinical practice context can harm patients. The tips provided can help clinicians infer judiciously from clinical trial results and avoid credulously accepting findings without critique. We suggest that statistical and mathematical expertise is unnecessary, but rather a keen curiosity about investigators' rationale for certain design choices and how these choices can affect results is key. For a more comprehensive understanding of clinical trials, this article can be used with the authors' corresponding ten tips article that focuses on designing a clinical trial.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	MARY ANN LIEBERT, INC
dc.relation.ispartof	J Palliat Med
dc.relation.isbasedon	10.1089/jpm.2024.0258
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1103 Clinical Sciences, 1110 Nursing, 1117 Public Health and Health Services
dc.subject.classification	Gerontology
dc.subject.classification	4203 Health services and systems
dc.subject.classification	4205 Nursing
dc.title	Top Ten Tips Palliative Care Clinicians Should Know About Interpreting a Clinical Trial.
dc.type	Journal Article
utslib.location.activity	United States
utslib.for	1103 Clinical Sciences
utslib.for	1110 Nursing
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Research Centres/IMPACCT
pubs.organisational-group	University of Technology Sydney/UTS Groups
pubs.organisational-group	University of Technology Sydney/UTS Groups/Improving Palliative, Aged and Chronic Care through Clinical Research and Translation (IMPACCT)
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Research Centres
utslib.copyright.status	closed_access	*
dc.date.updated	2024-10-03T06:55:45Z
pubs.publication-status	Published online

Abstract:

Evidence-based practice is foundational to high-quality palliative care delivery. However, the clinical trials that compose the evidence base are often methodologically imperfect. Applying their conclusions without critical application to the clinical practice context can harm patients. The tips provided can help clinicians infer judiciously from clinical trial results and avoid credulously accepting findings without critique. We suggest that statistical and mathematical expertise is unnecessary, but rather a keen curiosity about investigators' rationale for certain design choices and how these choices can affect results is key. For a more comprehensive understanding of clinical trials, this article can be used with the authors' corresponding ten tips article that focuses on designing a clinical trial.

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http://hdl.handle.net/10453/181172