A pre-post study of pharmacist-led medication reviews within a hospital-based residential aged care support service.

Chan, J; Bolitho, R; Hay, K; Yong, F

A pre-post study of pharmacist-led medication reviews within a hospital-based residential aged care support service.

Chan, J Bolitho, R Hay, K Yong, F

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Publisher:: OXFORD UNIV PRESS
Publication Type:: Journal Article
Citation:: Int J Pharm Pract, 2024, 32, (4), pp. 303-310
Issue Date:: 2024-07-04

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Field	Value	Language
dc.contributor.author	Chan, J
dc.contributor.author	Bolitho, R
dc.contributor.author	Hay, K
dc.contributor.author	Yong, F https://orcid.org/0000-0002-4878-7565
dc.date.accessioned	2024-10-04T04:24:44Z
dc.date.available	2024-04-12
dc.date.available	2024-10-04T04:24:44Z
dc.date.issued	2024-07-04
dc.identifier.citation	Int J Pharm Pract, 2024, 32, (4), pp. 303-310
dc.identifier.issn	0961-7671
dc.identifier.issn	2042-7174
dc.identifier.uri	http://hdl.handle.net/10453/181187
dc.description.abstract	BACKGROUND: Hospital-based residential aged-care support service teams typically consist of doctors and nurses who provide hospital substitutive care to aged-care residents. There is limited literature evaluating the pharmacist's role in such aged-care support teams. OBJECTIVE: To analyse the effect of residential aged-care support service pharmacist-led medication reviews on polypharmacy, drug burden index, potentially inappropriate medications, and potential prescribing omissions for aged-care residents. METHODS: Residents referred to a residential aged-care support service pharmacist for medication review over a 12-month period were included. The pharmacist communicated medication-related problems and recommendations to the resident's general practitioner and residential aged-care support service medical practitioner. Residents' medication histories were obtained at baseline and one-month postintervention. The number of medications and their associated drug burden indices were compared using paired t-tests; potentially inappropriate medications and potential prescribing omissions were compared using Wilcoxon's signed rank test. KEY FINDINGS: Of 175 residents (mean age 84 years) referred for pharmacist-led medication review, 146 had postintervention evaluation after one-month (median 29 days). Mean number of medications reduced from 12.47 at baseline to 11.84 postintervention (mean difference (95% CI): 0.63(0.33-0.93), P < .001). Mean drug burden index score reduced from 1.54 at baseline to 1.37 postintervention (mean difference (95% CI): 0.17(0.10-0.24), P < .001). More residents experienced a decrease in inappropriate medications (median (IQR) pre: 2(1-3), post: 1(0-2), P < .001) and prescribing omissions (median (IQR) pre: 0(0-1), post: 0(0-0), P = .003) compared with those that had an increase. CONCLUSIONS: Medication reviews performed by pharmacists embedded in hospital-based residential aged-care support services may improve medication prescribing. Further research into such preventative health service models is required.
dc.format	Print
dc.language	eng
dc.publisher	OXFORD UNIV PRESS
dc.relation.ispartof	Int J Pharm Pract
dc.relation.isbasedon	10.1093/ijpp/riae018
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences
dc.subject.classification	Pharmacology & Pharmacy
dc.subject.classification	3214 Pharmacology and pharmaceutical sciences
dc.subject.mesh	Humans
dc.subject.mesh	Aged, 80 and over
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Aged
dc.subject.mesh	Pharmacists
dc.subject.mesh	Polypharmacy
dc.subject.mesh	Professional Role
dc.subject.mesh	Inappropriate Prescribing
dc.subject.mesh	Homes for the Aged
dc.subject.mesh	Practice Patterns, Pharmacists'
dc.subject.mesh	Potentially Inappropriate Medication List
dc.subject.mesh	Pharmacy Service, Hospital
dc.subject.mesh	Humans
dc.subject.mesh	Polypharmacy
dc.subject.mesh	Professional Role
dc.subject.mesh	Aged
dc.subject.mesh	Aged, 80 and over
dc.subject.mesh	Pharmacists
dc.subject.mesh	Pharmacy Service, Hospital
dc.subject.mesh	Homes for the Aged
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Inappropriate Prescribing
dc.subject.mesh	Potentially Inappropriate Medication List
dc.subject.mesh	Practice Patterns, Pharmacists'
dc.subject.mesh	Humans
dc.subject.mesh	Aged, 80 and over
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Aged
dc.subject.mesh	Pharmacists
dc.subject.mesh	Polypharmacy
dc.subject.mesh	Professional Role
dc.subject.mesh	Inappropriate Prescribing
dc.subject.mesh	Homes for the Aged
dc.subject.mesh	Practice Patterns, Pharmacists'
dc.subject.mesh	Potentially Inappropriate Medication List
dc.subject.mesh	Pharmacy Service, Hospital
dc.title	A pre-post study of pharmacist-led medication reviews within a hospital-based residential aged care support service.
dc.type	Journal Article
utslib.citation.volume	32
utslib.location.activity	England
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated	2024-10-04T04:24:41Z
pubs.issue	4
pubs.publication-status	Published
pubs.volume	32
utslib.citation.issue	4

Abstract:

BACKGROUND: Hospital-based residential aged-care support service teams typically consist of doctors and nurses who provide hospital substitutive care to aged-care residents. There is limited literature evaluating the pharmacist's role in such aged-care support teams. OBJECTIVE: To analyse the effect of residential aged-care support service pharmacist-led medication reviews on polypharmacy, drug burden index, potentially inappropriate medications, and potential prescribing omissions for aged-care residents. METHODS: Residents referred to a residential aged-care support service pharmacist for medication review over a 12-month period were included. The pharmacist communicated medication-related problems and recommendations to the resident's general practitioner and residential aged-care support service medical practitioner. Residents' medication histories were obtained at baseline and one-month postintervention. The number of medications and their associated drug burden indices were compared using paired t-tests; potentially inappropriate medications and potential prescribing omissions were compared using Wilcoxon's signed rank test. KEY FINDINGS: Of 175 residents (mean age 84 years) referred for pharmacist-led medication review, 146 had postintervention evaluation after one-month (median 29 days). Mean number of medications reduced from 12.47 at baseline to 11.84 postintervention (mean difference (95% CI): 0.63(0.33-0.93), P < .001). Mean drug burden index score reduced from 1.54 at baseline to 1.37 postintervention (mean difference (95% CI): 0.17(0.10-0.24), P < .001). More residents experienced a decrease in inappropriate medications (median (IQR) pre: 2(1-3), post: 1(0-2), P < .001) and prescribing omissions (median (IQR) pre: 0(0-1), post: 0(0-0), P = .003) compared with those that had an increase. CONCLUSIONS: Medication reviews performed by pharmacists embedded in hospital-based residential aged-care support services may improve medication prescribing. Further research into such preventative health service models is required.

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http://hdl.handle.net/10453/181187