Innovations in pharmacovigilance studies of medicines in older people.
- Publisher:
- WILEY
- Publication Type:
- Journal Article
- Citation:
- Br J Clin Pharmacol, 2025, 91, (1), pp. 66-83
- Issue Date:
- 2025-01
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Full metadata record
Field | Value | Language |
---|---|---|
dc.contributor.author | Kalisch Ellett, LM | |
dc.contributor.author | Janetzki, JL | |
dc.contributor.author | Lim, R | |
dc.contributor.author | Laba, T-L | |
dc.contributor.author | Pratt, NL | |
dc.date.accessioned | 2025-01-28T05:32:18Z | |
dc.date.available | 2024-02-24 | |
dc.date.available | 2025-01-28T05:32:18Z | |
dc.date.issued | 2025-01 | |
dc.identifier.citation | Br J Clin Pharmacol, 2025, 91, (1), pp. 66-83 | |
dc.identifier.issn | 0306-5251 | |
dc.identifier.issn | 1365-2125 | |
dc.identifier.uri | http://hdl.handle.net/10453/184337 | |
dc.description.abstract | Pharmacovigilance is defined by the World Health Organization as "the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine/vaccine related problem". Pharmacovigilance studies are critical for detecting and assessing adverse events of medicines that may not have been observed in clinical trials. This activity is especially important in older people who are often excluded from clinical trials as they have multiple chronic conditions and use multiple medicines for longer durations than the clinical trials. In this narrative review we describe innovative methods in pharmacovigilance studies of medicines in older people that leverage the increasing availability of digital health technologies, electronic health records and real-world health data to identify and quantify medication related harms in older people. | |
dc.format | Print-Electronic | |
dc.language | eng | |
dc.publisher | WILEY | |
dc.relation.ispartof | Br J Clin Pharmacol | |
dc.relation.isbasedon | 10.1111/bcp.16049 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | 1115 Pharmacology and Pharmaceutical Sciences | |
dc.subject.classification | Pharmacology & Pharmacy | |
dc.subject.classification | 3214 Pharmacology and pharmaceutical sciences | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Adverse Drug Reaction Reporting Systems | |
dc.subject.mesh | Drug-Related Side Effects and Adverse Reactions | |
dc.subject.mesh | Electronic Health Records | |
dc.subject.mesh | Pharmacovigilance | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Adverse Drug Reaction Reporting Systems | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Electronic Health Records | |
dc.subject.mesh | Pharmacovigilance | |
dc.subject.mesh | Drug-Related Side Effects and Adverse Reactions | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Adverse Drug Reaction Reporting Systems | |
dc.subject.mesh | Drug-Related Side Effects and Adverse Reactions | |
dc.subject.mesh | Electronic Health Records | |
dc.subject.mesh | Pharmacovigilance | |
dc.title | Innovations in pharmacovigilance studies of medicines in older people. | |
dc.type | Journal Article | |
utslib.citation.volume | 91 | |
utslib.location.activity | England | |
utslib.for | 1115 Pharmacology and Pharmaceutical Sciences | |
pubs.organisational-group | University of Technology Sydney | |
pubs.organisational-group | University of Technology Sydney/Faculty of Health | |
pubs.organisational-group | University of Technology Sydney/UTS Groups | |
pubs.organisational-group | University of Technology Sydney/UTS Groups/INSIGHT: Institute for Innovative Solutions for Well-being and Health/Centre for Health Economics Research and Evaluation (CHERE) | |
pubs.organisational-group | University of Technology Sydney/UTS Groups/INSIGHT: Institute for Innovative Solutions for Well-being and Health | |
pubs.organisational-group | University of Technology Sydney/UTS Groups/INSIGHT: Institute for Innovative Solutions for Well-being and Health/Centre for Health Economics Research and Evaluation (CHERE)/Centre for Health Economics Research and Evaluation (CHERE) Associate Members | |
utslib.copyright.status | open_access | * |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.date.updated | 2025-01-28T05:32:17Z | |
pubs.issue | 1 | |
pubs.publication-status | Published | |
pubs.volume | 91 | |
utslib.citation.issue | 1 |
Abstract:
Pharmacovigilance is defined by the World Health Organization as "the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine/vaccine related problem". Pharmacovigilance studies are critical for detecting and assessing adverse events of medicines that may not have been observed in clinical trials. This activity is especially important in older people who are often excluded from clinical trials as they have multiple chronic conditions and use multiple medicines for longer durations than the clinical trials. In this narrative review we describe innovative methods in pharmacovigilance studies of medicines in older people that leverage the increasing availability of digital health technologies, electronic health records and real-world health data to identify and quantify medication related harms in older people.
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