Malnutrition in Colorectal Cancer Patients: Association with the Lack of Eating Motivation and Inappropriate Diet.

Ngoc Anh, LT; Kien, TG; Tuan, NV; Tuong, TTA; Ko, J; Dan, PT; Cho, J; Tap, NV

Malnutrition in Colorectal Cancer Patients: Association with the Lack of Eating Motivation and Inappropriate Diet.

Ngoc Anh, LT Kien, TG Tuan, NV Tuong, TTA Ko, J Dan, PT Cho, J Tap, NV

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Publisher:: EpiSmart Science Vector
Publication Type:: Journal Article
Citation:: Asian Pac J Cancer Prev, 2025, 26, (5), pp. 1661-1670
Issue Date:: 2025-05-01

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Field	Value	Language
dc.contributor.author	Ngoc Anh, LT
dc.contributor.author	Kien, TG
dc.contributor.author	Tuan, NV
dc.contributor.author	Tuong, TTA
dc.contributor.author	Ko, J
dc.contributor.author	Dan, PT
dc.contributor.author	Cho, J
dc.contributor.author	Tap, NV
dc.date.accessioned	2025-12-09T03:56:27Z
dc.date.available	2025-12-09T03:56:27Z
dc.date.issued	2025-05-01
dc.identifier.citation	Asian Pac J Cancer Prev, 2025, 26, (5), pp. 1661-1670
dc.identifier.issn	1513-7368
dc.identifier.issn	2476-762X
dc.identifier.uri	http://hdl.handle.net/10453/190891
dc.description.abstract	OBJECTIVE: Colorectal cancer (CRC) significantly contributes to cancer-related mortality in Vietnam. Notably, malnutrition, rather than cancer itself, accounts for one-fifth of the deaths among cancer patients. Therefore, understanding the nutritional status and related factors among CRC patients is essential. We aimed to investigate the nutritional status and related factors in CRC in Vietnam. METHODS: This cross-sectional study, conducted from October 2022 to April 2023, included CRCs of both sexes aged ≥18 years. Data collection involved face-to-face interviews, anthropometric assessments, and medical record reviews. Nutritional status was evaluated using the Patient-Generated Subjective Global Assessment (PG-SGA). Multivariable logistic regression was used to identify malnutrition-related factors. RESULTS: In total, 388 patients were included (median age, 60.0 years, [IQR: 51.0-66.0 years]; men, 57.7%). The prevalence of malnutrition was 87.9% (95%CI: 84.6-91.1), and urgent nutritional intervention was needed in 64.7% of participants. Malnutrition-associated factors included lack of eating motivation (OR=8.76, 95%CI: 1.81-42.38), dieting for fear of cancer cell growth (OR=3.82, 95%CI: 1.27-11.52), gastrointestinal symptoms (OR=5.38, 95%CI: 1.76-16.45), daily energy intake <25kcal/kg (OR=7.02, 95%CI: 1.70-28.99), protein ≤ 1g/kg (OR=5.21, 95%CI: 1.32-20.60), fat <18% of total energy intake (OR=3.13, 95%CI: 1.02-9.57), mean corpuscular volume <85fL (OR=4.74, 95%CI: 1.11-20.22), and total lymphocyte count ≤1700 lymphocytes/mm3 (OR=4.06, 95%CI: 1.22-13.50). Additionally, a 1-kg increase in dominant hand strength reduced the risk of malnutrition by 4% (OR=0.96, 95%CI: 0.93-0.99). CONCLUSION: The high prevalence of malnutrition among CRCs in Vietnam necessitates nutritional intervention. The main contributors include loss of eating motivation and inadequate dietary intake.
dc.format	Electronic
dc.language	eng
dc.publisher	EpiSmart Science Vector
dc.relation.ispartof	Asian Pac J Cancer Prev
dc.relation.isbasedon	10.31557/APJCP.2025.26.5.1661
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1103 Clinical Sciences, 1112 Oncology and Carcinogenesis, 1117 Public Health and Health Services
dc.subject.classification	Oncology & Carcinogenesis
dc.subject.classification	3211 Oncology and carcinogenesis
dc.subject.classification	4202 Epidemiology
dc.subject.classification	4206 Public health
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Female
dc.subject.mesh	Colorectal Neoplasms
dc.subject.mesh	Middle Aged
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Malnutrition
dc.subject.mesh	Aged
dc.subject.mesh	Motivation
dc.subject.mesh	Nutritional Status
dc.subject.mesh	Vietnam
dc.subject.mesh	Prognosis
dc.subject.mesh	Follow-Up Studies
dc.subject.mesh	Prevalence
dc.subject.mesh	Feeding Behavior
dc.subject.mesh	Diet
dc.subject.mesh	Humans
dc.subject.mesh	Colorectal Neoplasms
dc.subject.mesh	Malnutrition
dc.subject.mesh	Prognosis
dc.subject.mesh	Diet
dc.subject.mesh	Prevalence
dc.subject.mesh	Follow-Up Studies
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Feeding Behavior
dc.subject.mesh	Motivation
dc.subject.mesh	Nutritional Status
dc.subject.mesh	Aged
dc.subject.mesh	Middle Aged
dc.subject.mesh	Vietnam
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Female
dc.subject.mesh	Colorectal Neoplasms
dc.subject.mesh	Middle Aged
dc.subject.mesh	Cross-Sectional Studies
dc.subject.mesh	Malnutrition
dc.subject.mesh	Aged
dc.subject.mesh	Motivation
dc.subject.mesh	Nutritional Status
dc.subject.mesh	Vietnam
dc.subject.mesh	Prognosis
dc.subject.mesh	Follow-Up Studies
dc.subject.mesh	Prevalence
dc.subject.mesh	Feeding Behavior
dc.subject.mesh	Diet
dc.title	Malnutrition in Colorectal Cancer Patients: Association with the Lack of Eating Motivation and Inappropriate Diet.
dc.type	Journal Article
utslib.citation.volume	26
utslib.location.activity	Thailand
utslib.for	1103 Clinical Sciences
utslib.for	1112 Oncology and Carcinogenesis
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	University of Technology Sydney/UTS Groups
pubs.organisational-group	University of Technology Sydney/UTS Groups/UTS Ageing Research Collaborative (UARC)
pubs.organisational-group	University of Technology Sydney/UTS Groups/INSIGHT: Institute for Innovative Solutions for Wellbeing and Health
pubs.organisational-group	University of Technology Sydney/UTS Groups/Centre for Health Technologies (CHT)
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by-nc/4.0/
dc.date.updated	2025-12-09T03:56:25Z
pubs.issue	5
pubs.publication-status	Published online
pubs.volume	26
utslib.citation.issue	5

Abstract:

OBJECTIVE: Colorectal cancer (CRC) significantly contributes to cancer-related mortality in Vietnam. Notably, malnutrition, rather than cancer itself, accounts for one-fifth of the deaths among cancer patients. Therefore, understanding the nutritional status and related factors among CRC patients is essential. We aimed to investigate the nutritional status and related factors in CRC in Vietnam. METHODS: This cross-sectional study, conducted from October 2022 to April 2023, included CRCs of both sexes aged ≥18 years. Data collection involved face-to-face interviews, anthropometric assessments, and medical record reviews. Nutritional status was evaluated using the Patient-Generated Subjective Global Assessment (PG-SGA). Multivariable logistic regression was used to identify malnutrition-related factors. RESULTS: In total, 388 patients were included (median age, 60.0 years, [IQR: 51.0-66.0 years]; men, 57.7%). The prevalence of malnutrition was 87.9% (95%CI: 84.6-91.1), and urgent nutritional intervention was needed in 64.7% of participants. Malnutrition-associated factors included lack of eating motivation (OR=8.76, 95%CI: 1.81-42.38), dieting for fear of cancer cell growth (OR=3.82, 95%CI: 1.27-11.52), gastrointestinal symptoms (OR=5.38, 95%CI: 1.76-16.45), daily energy intake <25kcal/kg (OR=7.02, 95%CI: 1.70-28.99), protein ≤ 1g/kg (OR=5.21, 95%CI: 1.32-20.60), fat <18% of total energy intake (OR=3.13, 95%CI: 1.02-9.57), mean corpuscular volume <85fL (OR=4.74, 95%CI: 1.11-20.22), and total lymphocyte count ≤1700 lymphocytes/mm3 (OR=4.06, 95%CI: 1.22-13.50). Additionally, a 1-kg increase in dominant hand strength reduced the risk of malnutrition by 4% (OR=0.96, 95%CI: 0.93-0.99). CONCLUSION: The high prevalence of malnutrition among CRCs in Vietnam necessitates nutritional intervention. The main contributors include loss of eating motivation and inadequate dietary intake.

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http://hdl.handle.net/10453/190891