Atmospheric aerosol-microplastics intake and deposition in the alveolar region by considering dynamic behavior of acinar airways.

Beni, HM; Mortazavi, H; Larpruenrudee, P; Gu, Y; Sauret, E; Islam, MS

Atmospheric aerosol-microplastics intake and deposition in the alveolar region by considering dynamic behavior of acinar airways.

Beni, HM Mortazavi, H Larpruenrudee, P

Gu, Y Sauret, E Islam, MS

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Publisher:: PUBLIC LIBRARY SCIENCE
Publication Type:: Journal Article
Citation:: PLoS One, 2025, 20, (8), pp. e0327416
Issue Date:: 2025

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Field	Value	Language
dc.contributor.author	Beni, HM
dc.contributor.author	Mortazavi, H
dc.contributor.author	Larpruenrudee, P https://orcid.org/0000-0002-3413-3667
dc.contributor.author	Gu, Y
dc.contributor.author	Sauret, E
dc.contributor.author	Islam, MS
dc.contributor.editor	Deng, X
dc.date.accessioned	2025-12-22T03:15:32Z
dc.date.available	2025-06-12
dc.date.available	2025-12-22T03:15:32Z
dc.date.issued	2025
dc.identifier.citation	PLoS One, 2025, 20, (8), pp. e0327416
dc.identifier.issn	1932-6203
dc.identifier.issn	1932-6203
dc.identifier.uri	http://hdl.handle.net/10453/191090
dc.description.abstract	BACKGROUND AND OBJECTIVE: Atmospheric aerosols from different industrial and natural sources enter the airways during inhalation. The smaller respirable aerosols enter the alveolar sacs and, depending on the residence time and toxicity, create severe respiratory health hazards. The physiological movement of the alveolar sacs is an important feature of breathing dynamics. Therefore, the knowledge of the dynamic behavior of the alveolar airways during airflow and aerosol transport is essential for the accurate health risk assessment of respiratory aerosols. METHODS: This study analyzed the physiological movements of the alveolar sac and its impact on airflow and particle deposition in the acinar region. In the present study, the dynamic acinar model uses a Computational Fluid-Particle Dynamics (CFPD). The boundary condition of moving walls is presented by introducing a novel strategic motion function of the alveoli (Eq. 5) compatible with the physiological function of the lung. RESULTS: The results of the present study indicated that particle density is a determining factor in increasing the percentage of particle pollution deposition lower than 3 µm. The study also reports that the air amplitude velocity (~0.01 vs. 0.00085 m/s) is a crucial index in the particle pollution deposition in alveoli. CONCLUSIONS: To date, several studies analyzed the airflow in acinar sections. However, a comprehensive analysis of the physiological behavior of the alveolar sacs is missing in the literature. The specific findings of this study would improve the knowledge of airborne particle transmission in the alveolar zone.
dc.format	Electronic-eCollection
dc.language	eng
dc.publisher	PUBLIC LIBRARY SCIENCE
dc.relation.ispartof	PLoS One
dc.relation.isbasedon	10.1371/journal.pone.0327416
dc.rights	info:eu-repo/semantics/openAccess
dc.subject.classification	General Science & Technology
dc.subject.mesh	Pulmonary Alveoli
dc.subject.mesh	Aerosols
dc.subject.mesh	Humans
dc.subject.mesh	Particle Size
dc.subject.mesh	Models, Biological
dc.subject.mesh	Hydrodynamics
dc.subject.mesh	Pulmonary Alveoli
dc.subject.mesh	Humans
dc.subject.mesh	Aerosols
dc.subject.mesh	Particle Size
dc.subject.mesh	Models, Biological
dc.subject.mesh	Hydrodynamics
dc.subject.mesh	Pulmonary Alveoli
dc.subject.mesh	Aerosols
dc.subject.mesh	Humans
dc.subject.mesh	Particle Size
dc.subject.mesh	Models, Biological
dc.subject.mesh	Hydrodynamics
dc.title	Atmospheric aerosol-microplastics intake and deposition in the alveolar region by considering dynamic behavior of acinar airways.
dc.type	Journal Article
utslib.citation.volume	20
utslib.location.activity	United States
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	University of Technology Sydney/Faculty of Engineering and Information Technology/School of Mechanical and Mechatronic Engineering
utslib.copyright.status	open_access	*
dc.rights.license	This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/
dc.date.updated	2025-12-22T03:15:29Z
pubs.issue	8
pubs.publication-status	Published online
pubs.volume	20
utslib.citation.issue	8

Abstract:

BACKGROUND AND OBJECTIVE: Atmospheric aerosols from different industrial and natural sources enter the airways during inhalation. The smaller respirable aerosols enter the alveolar sacs and, depending on the residence time and toxicity, create severe respiratory health hazards. The physiological movement of the alveolar sacs is an important feature of breathing dynamics. Therefore, the knowledge of the dynamic behavior of the alveolar airways during airflow and aerosol transport is essential for the accurate health risk assessment of respiratory aerosols. METHODS: This study analyzed the physiological movements of the alveolar sac and its impact on airflow and particle deposition in the acinar region. In the present study, the dynamic acinar model uses a Computational Fluid-Particle Dynamics (CFPD). The boundary condition of moving walls is presented by introducing a novel strategic motion function of the alveoli (Eq. 5) compatible with the physiological function of the lung. RESULTS: The results of the present study indicated that particle density is a determining factor in increasing the percentage of particle pollution deposition lower than 3 µm. The study also reports that the air amplitude velocity (~0.01 vs. 0.00085 m/s) is a crucial index in the particle pollution deposition in alveoli. CONCLUSIONS: To date, several studies analyzed the airflow in acinar sections. However, a comprehensive analysis of the physiological behavior of the alveolar sacs is missing in the literature. The specific findings of this study would improve the knowledge of airborne particle transmission in the alveolar zone.

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http://hdl.handle.net/10453/191090