The clinical utility of routine urinalysis in pregnancy: A prospective study

Murray, N; Homer, CSE; Davis, GK; Curtis, J; Mangos, G; Brown, MA

The clinical utility of routine urinalysis in pregnancy: A prospective study

Murray, N Homer, CSE

Davis, GK Curtis, J Mangos, G Brown, MA

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Publication Type:: Journal Article
Citation:: Medical Journal of Australia, 2002, 177 (9), pp. 477 - 480
Issue Date:: 2002-11-04

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Field	Value	Language
dc.contributor.author	Murray, N	en_US
dc.contributor.author	Homer, CSE https://orcid.org/0000-0002-7454-3011	en_US
dc.contributor.author	Davis, GK	en_US
dc.contributor.author	Curtis, J	en_US
dc.contributor.author	Mangos, G	en_US
dc.contributor.author	Brown, MA	en_US
dc.date.available	2002-06-26	en_US
dc.date.issued	2002-11-04	en_US
dc.identifier.citation	Medical Journal of Australia, 2002, 177 (9), pp. 477 - 480	en_US
dc.identifier.issn	0025-729X	en_US
dc.identifier.uri	http://hdl.handle.net/10453/4538
dc.description.abstract	Objectives: To determine whether routine urinalysis in the antenatal period facilitates diagnosis of pre-eclampsia. Can routine urinalysis during pregnancy be discontinue in women with normal results of dipstick urinalysis and microscopy at the first antenatal visit? Design: Prospective observational study. Setting: A metropolitan public hospital and a private hospital in Sydney (NSW). Participants: One thousand women were enrolled at their first antenatal visit (March to November 1999), and 913 completed the study. Outcome measures: The primary outcome was a diagnosis of de novo hypertension (gestational hypertension, pre-eclampasia, or pre-eclampsia superimposed on chronic hypertension). Results: Thirty-five women had dipstick proteinuria at the first antenatal visit. In 25 (71%) of these women, further dipstick proteinuria was detected during pregnancy, and two (6%) were diagnosed with pre-eclampsia. Of the 867 without dipstick proteinuria at the first visit, 338 (39%) had dipstick proteinuria (> 1+) at some time during pregnancy. There were no statistically significant differences in the proportion of women with and without dipstick proteinuria at their first visit who developed hypertension during pregnancy. Only six women developed proteinuria before the onset of hypertension. Women who had an abnormal result of a midstream urine test at their first visit, compared with women with a normal result, were more likely to have a urinary tract infection diagnosed during pregnancy; however, the numbers were small. Conclusion: In the absence of hypertension, routine urinalysis during pregnancy is a poor predictor of pre-eclampsia. Therefore, after an initial screening urinalysis, routine urinalysis could be eliminated from antenatal care without adverse outcomes for women.	en_US
dc.relation.ispartof	Medical Journal of Australia	en_US
dc.subject.classification	General & Internal Medicine	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Pregnancy Complications, Infectious	en_US
dc.subject.mesh	Urinary Tract Infections	en_US
dc.subject.mesh	Proteinuria	en_US
dc.subject.mesh	Pre-Eclampsia	en_US
dc.subject.mesh	Pregnancy Complications, Cardiovascular	en_US
dc.subject.mesh	Hypertension	en_US
dc.subject.mesh	Creatinine	en_US
dc.subject.mesh	Reagent Strips	en_US
dc.subject.mesh	Urinalysis	en_US
dc.subject.mesh	Diagnostic Tests, Routine	en_US
dc.subject.mesh	Prenatal Care	en_US
dc.subject.mesh	Prospective Studies	en_US
dc.subject.mesh	Pregnancy	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Female	en_US
dc.title	The clinical utility of routine urinalysis in pregnancy: A prospective study	en_US
dc.type	Journal Article
utslib.citation.volume	9	en_US
utslib.citation.volume	177	en_US
utslib.for	111717 Primary Health Care	en_US
utslib.for	111006 Midwifery	en_US
utslib.for	11 Medical and Health Sciences	en_US
utslib.for	17 Psychology and Cognitive Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	/University of Technology Sydney/Strength - WHO CC
utslib.copyright.status	open_access
pubs.issue	9	en_US
pubs.publication-status	Published	en_US
pubs.volume	177	en_US

Abstract:

Objectives: To determine whether routine urinalysis in the antenatal period facilitates diagnosis of pre-eclampsia. Can routine urinalysis during pregnancy be discontinue in women with normal results of dipstick urinalysis and microscopy at the first antenatal visit? Design: Prospective observational study. Setting: A metropolitan public hospital and a private hospital in Sydney (NSW). Participants: One thousand women were enrolled at their first antenatal visit (March to November 1999), and 913 completed the study. Outcome measures: The primary outcome was a diagnosis of de novo hypertension (gestational hypertension, pre-eclampasia, or pre-eclampsia superimposed on chronic hypertension). Results: Thirty-five women had dipstick proteinuria at the first antenatal visit. In 25 (71%) of these women, further dipstick proteinuria was detected during pregnancy, and two (6%) were diagnosed with pre-eclampsia. Of the 867 without dipstick proteinuria at the first visit, 338 (39%) had dipstick proteinuria (> 1+) at some time during pregnancy. There were no statistically significant differences in the proportion of women with and without dipstick proteinuria at their first visit who developed hypertension during pregnancy. Only six women developed proteinuria before the onset of hypertension. Women who had an abnormal result of a midstream urine test at their first visit, compared with women with a normal result, were more likely to have a urinary tract infection diagnosed during pregnancy; however, the numbers were small. Conclusion: In the absence of hypertension, routine urinalysis during pregnancy is a poor predictor of pre-eclampsia. Therefore, after an initial screening urinalysis, routine urinalysis could be eliminated from antenatal care without adverse outcomes for women.

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http://hdl.handle.net/10453/4538