Effects of creatine supplementation on aerobic power and cardiovascular structure and function

Murphy, AJ; Watsford, ML; Coutts, AJ; Richards, DAB

Effects of creatine supplementation on aerobic power and cardiovascular structure and function

Murphy, AJ Watsford, ML

Coutts, AJ

Richards, DAB

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Publication Type:: Journal Article
Citation:: Journal of Science and Medicine in Sport, 2005, 8 (3), pp. 305 - 313
Issue Date:: 2005-01-01

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Field	Value	Language
dc.contributor.author	Murphy, AJ	en_US
dc.contributor.author	Watsford, ML https://orcid.org/0000-0002-4569-6377	en_US
dc.contributor.author	Coutts, AJ https://orcid.org/0000-0002-1782-7691	en_US
dc.contributor.author	Richards, DAB	en_US
dc.date.issued	2005-01-01	en_US
dc.identifier.citation	Journal of Science and Medicine in Sport, 2005, 8 (3), pp. 305 - 313	en_US
dc.identifier.issn	1440-2440	en_US
dc.identifier.uri	http://hdl.handle.net/10453/4758
dc.description.abstract	This project aimed to determine 1) whether creatine (Cr) supplementation affects cardiovascular structure and function and 2) to examine its effect on aerobic power. Eighteen males undertook aerobic testing on a cycle ergometer and echocardiographic assessment of the heart. The experimental group (N=9) ingested 20g·day-1 of Cr for seven days followed by 10g·day-1 for a further 21 days. The control group (N=9) followed an identical protocol ingesting a placebo for the same period. Assessment was performed pre-, mid- (seven days) and post-testing (28 days). A MANOVA with repeated measures was used to test for group differences before and after supplementation. The Cr group demonstrated a significant increase in body mass for the pre-mid (1.0±0.6 kg) and the pre-post (1.5±0.7 kg) testing occasions. Submaximal V̇O2 decreased significantly from the pre-mid and pre-post testing occasions by between 4.8% to 11.4% with Cr supplementation at workloads of 75 W and 150 W. Other oxygen consumption measures and exercise time to exhaustion, for the Cr group, showed decreasing trends that approached significance. Additionally, there was a significant pre-post decrease in maximum heart rate of 3.7%. There were no changes in any of the echocardiographic or blood pressure measures for either group. The present results suggest short term Cr supplementation has no detectable negative effect on cardiac structure or function. Additionally, Cr ingestion improves submaximal cycling efficiency. These results suggest that the increase in efficiency may be related to peripheral factors such an increase in muscle phosphocreatine, rather than central changes.	en_US
dc.relation.ispartof	Journal of Science and Medicine in Sport	en_US
dc.relation.isbasedon	10.1016/S1440-2440(05)80041-6	en_US
dc.subject.classification	Sport Sciences	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Creatine	en_US
dc.subject.mesh	Echocardiography	en_US
dc.subject.mesh	Body Mass Index	en_US
dc.subject.mesh	Analysis of Variance	en_US
dc.subject.mesh	Ergometry	en_US
dc.subject.mesh	Oxygen Consumption	en_US
dc.subject.mesh	Heart Rate	en_US
dc.subject.mesh	Coronary Circulation	en_US
dc.subject.mesh	Physical Endurance	en_US
dc.subject.mesh	Dietary Supplements	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Male	en_US
dc.title	Effects of creatine supplementation on aerobic power and cardiovascular structure and function	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	8	en_US
utslib.for	110604 Sports Medicine	en_US
utslib.for	110602 Exercise Physiology	en_US
utslib.for	1106 Human Movement and Sports Sciences	en_US
utslib.for	1116 Medical Physiology	en_US
utslib.for	1117 Public Health and Health Services	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Sports and Exercise Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	8	en_US

Abstract:

This project aimed to determine 1) whether creatine (Cr) supplementation affects cardiovascular structure and function and 2) to examine its effect on aerobic power. Eighteen males undertook aerobic testing on a cycle ergometer and echocardiographic assessment of the heart. The experimental group (N=9) ingested 20g·day-1 of Cr for seven days followed by 10g·day-1 for a further 21 days. The control group (N=9) followed an identical protocol ingesting a placebo for the same period. Assessment was performed pre-, mid- (seven days) and post-testing (28 days). A MANOVA with repeated measures was used to test for group differences before and after supplementation. The Cr group demonstrated a significant increase in body mass for the pre-mid (1.0±0.6 kg) and the pre-post (1.5±0.7 kg) testing occasions. Submaximal V̇O2 decreased significantly from the pre-mid and pre-post testing occasions by between 4.8% to 11.4% with Cr supplementation at workloads of 75 W and 150 W. Other oxygen consumption measures and exercise time to exhaustion, for the Cr group, showed decreasing trends that approached significance. Additionally, there was a significant pre-post decrease in maximum heart rate of 3.7%. There were no changes in any of the echocardiographic or blood pressure measures for either group. The present results suggest short term Cr supplementation has no detectable negative effect on cardiac structure or function. Additionally, Cr ingestion improves submaximal cycling efficiency. These results suggest that the increase in efficiency may be related to peripheral factors such an increase in muscle phosphocreatine, rather than central changes.

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http://hdl.handle.net/10453/4758