Using discrete choice experiments to investigate subject preferences for preventive asthma medication

Lancsar, EJ; Hall, JP; King, M; Kenny, P; Louviere, JJ; Fiebig, DG; Hossain, I; Thien, FCK; Reddel, HK; Jenkins, CR

Using discrete choice experiments to investigate subject preferences for preventive asthma medication

Lancsar, EJ

Hall, JP

King, M Kenny, P

Louviere, JJ Fiebig, DG

Hossain, I Thien, FCK Reddel, HK Jenkins, CR

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Publication Type:: Journal Article
Citation:: Respirology, 2007, 12 (1), pp. 127 - 136
Issue Date:: 2007-01-01

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Field	Value	Language
dc.contributor.author	Lancsar, EJ https://orcid.org/0000-0003-2404-6735	en_US
dc.contributor.author	Hall, JP https://orcid.org/0000-0002-2191-0543	en_US
dc.contributor.author	King, M	en_US
dc.contributor.author	Kenny, P https://orcid.org/0000-0002-5021-4758	en_US
dc.contributor.author	Louviere, JJ	en_US
dc.contributor.author	Fiebig, DG https://orcid.org/0000-0002-3707-1940	en_US
dc.contributor.author	Hossain, I	en_US
dc.contributor.author	Thien, FCK	en_US
dc.contributor.author	Reddel, HK	en_US
dc.contributor.author	Jenkins, CR	en_US
dc.date.issued	2007-01-01	en_US
dc.identifier.citation	Respirology, 2007, 12 (1), pp. 127 - 136	en_US
dc.identifier.issn	1323-7799	en_US
dc.identifier.uri	http://hdl.handle.net/10453/4818
dc.description.abstract	Background and objective: Long-term adherence to inhaled corticosteroids is poor despite the crucial role of preventer medications in achieving good asthma outcomes. This study was undertaken to explore patient preferences in relation to their current inhaled corticosteroid medication, a hypothetical preventer or no medication. Methods: A discrete choice experiment was conducted in 57 adults with mild-moderate asthma and airway hyper-responsiveness, who were using inhaled corticosteroid ≤500 μg/day (beclomethasone equivalent). In the discrete choice experiment, subjects evaluated 16 hypothetical scenarios made up of 10 attributes that described the process and outcomes of taking asthma medication, with two to four levels for each attribute. For each scenario, subjects chose between the hypothetical medication, the medication they were currently taking and no asthma medication. A random parameter multinomial logit model was estimated to quantify subject preferences for the aspects of taking asthma medication and the influence of attributes on medication decisions. Results: Subjects consistently made choices in favour of being able to do strenuous and sporting activities with or without reliever, experiencing no side-effects and never having to monitor their peak flow. Frequency of collecting prescriptions, frequency of taking the medication, its route of administration and the strength of the doctor recommendation about the medication were not significant determinants of choice. Conclusions: The results of this study suggest that patients prefer a preventer that confers capacity to maximize physical activity, has no side-effects and does not require daily peak flow monitoring. © 2007 The Authors.	en_US
dc.relation.ispartof	Respirology	en_US
dc.relation.isbasedon	10.1111/j.1440-1843.2006.01005.x	en_US
dc.subject.classification	Respiratory System	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Asthma	en_US
dc.subject.mesh	Glucocorticoids	en_US
dc.subject.mesh	Treatment Outcome	en_US
dc.subject.mesh	Administration, Inhalation	en_US
dc.subject.mesh	Severity of Illness Index	en_US
dc.subject.mesh	Prevalence	en_US
dc.subject.mesh	Follow-Up Studies	en_US
dc.subject.mesh	Patient Compliance	en_US
dc.subject.mesh	Time Factors	en_US
dc.subject.mesh	Quality of Life	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	Patient Satisfaction	en_US
dc.subject.mesh	Australia	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.title	Using discrete choice experiments to investigate subject preferences for preventive asthma medication	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	12	en_US
utslib.for	1117 Public Health and Health Services	en_US
utslib.for	11 Medical and Health Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Business
pubs.organisational-group	/University of Technology Sydney/Strength - CENSOC - Study of Choice
pubs.organisational-group	/University of Technology Sydney/Strength - CHERE - Centre for Health Economics Research and Evaluation
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	12	en_US

Abstract:

Background and objective: Long-term adherence to inhaled corticosteroids is poor despite the crucial role of preventer medications in achieving good asthma outcomes. This study was undertaken to explore patient preferences in relation to their current inhaled corticosteroid medication, a hypothetical preventer or no medication. Methods: A discrete choice experiment was conducted in 57 adults with mild-moderate asthma and airway hyper-responsiveness, who were using inhaled corticosteroid ≤500 μg/day (beclomethasone equivalent). In the discrete choice experiment, subjects evaluated 16 hypothetical scenarios made up of 10 attributes that described the process and outcomes of taking asthma medication, with two to four levels for each attribute. For each scenario, subjects chose between the hypothetical medication, the medication they were currently taking and no asthma medication. A random parameter multinomial logit model was estimated to quantify subject preferences for the aspects of taking asthma medication and the influence of attributes on medication decisions. Results: Subjects consistently made choices in favour of being able to do strenuous and sporting activities with or without reliever, experiencing no side-effects and never having to monitor their peak flow. Frequency of collecting prescriptions, frequency of taking the medication, its route of administration and the strength of the doctor recommendation about the medication were not significant determinants of choice. Conclusions: The results of this study suggest that patients prefer a preventer that confers capacity to maximize physical activity, has no side-effects and does not require daily peak flow monitoring. © 2007 The Authors.

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http://hdl.handle.net/10453/4818